Results 91 to 100 of about 51,828 (245)

Association between initial 30‐day cumulative clozapine dose and risk of agranulocytosis: A nationwide register‐based cohort study

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Aims Clozapine‐induced agranulocytosis (CIA) is traditionally considered an idiosyncratic, dose‐independent reaction. However, emerging evidence suggests that clozapine‐related inflammatory events may exhibit dose‐dependent characteristics, leading us to hypothesize that CIA risk may similarly relate to early cumulative exposure.
Yuki Kikuchi   +5 more
wiley   +1 more source

Chlorpromazine-Induced Severe Hyponatremia in 66 Years Old Patient

open access: yesActa Medica Indonesiana, 2023
Hyponatremia is a common clinical problem in older people. The aging process is usually accompanied by various maladaptations to stress in different organs and physiologic functions.
Sri Soenarti, Muchammad Kamal Hadi
doaj  

Characterizing social motivation deficits in treatment‐resistant schizophrenia: Evidence from social incentive performance

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Aim The Treatment‐Response‐and‐Resistance‐in‐Psychosis (TRRIP) criteria recognizes negative symptoms as defining features for treatment‐resistant schizophrenia (TRS). Social motivation refers to the desire to pursue social reward (and to avoid social punishment).
Simon S.Y. Lui   +11 more
wiley   +1 more source

Circular inference in visual cortical hierarchies in schizophrenia

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Aim In schizophrenia, disrupted perceptual processes contribute to positive symptoms. However, it remains unclear how top‐down priors and bottom‐up likelihoods are represented across the hierarchy of visual cortices. To identify these processes within cortical hierarchies, the circular inference model offers a framework to account for the biased ...
Shuhei Hara   +7 more
wiley   +1 more source

Beat‐to‐beat variability of ventricular repolarization reveals sex‐specific instability and proarrhythmic risk

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato   +3 more
wiley   +1 more source

IN VITRO EFFECTS OF CHLORPROMAZINE AND HALOPERIDOL ON HUMAN ERYTHROCYTE GLUCOSE 6-PHOSPHATE DEHYDROGENASE ENZYME

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Objective: Effects of chlorpromazine and haloperidol on erythrocyte glucose 6-phosphate dehydrogenase enzyme activity were investigated in invitro conditions. Methods: Glucose 6- phosphate dehydrogenase was purified from human erythrocyte.
Mehmet Emin Büyükokuroğlu   +4 more
doaj  

Trial‐History Effects During WCST in Treatment‐Resistant Schizophrenia

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
In the WCST, participants must use feedback from each trial to update their subsequent choices. Trial‐level analysis revealed that previous‐trial correctness modulated reaction time, with a weaker post‐error slowing‐like effect in TRS compared with non‐TRS participants.
Ryo Sawagashira   +4 more
wiley   +1 more source

A Hidden History of Unhappiness

open access: yes
Critical Quarterly, EarlyView.
Joe Moran
wiley   +1 more source

A Scoping Review of 5‐HT3 Antagonist Antiemetic Medication Safety in the Management of Nausea and Vomiting of Pregnancy

open access: yesPharmacoepidemiology and Drug Safety, Volume 35, Issue 9, September 2026.
ABSTRACT Purpose The prescribing of 5‐hydroxytryptamine 3 receptor and type 3 serotonin receptor (5‐HT3) antagonists, particularly ondansetron, for nausea and vomiting in pregnancy (NVP) has increased globally. However, evidence on the safety of these medications in pregnancy remains unclear.
Shannon Morgan   +6 more
wiley   +1 more source

Allergy to chlorpromazine and valproic acid following carbamazepine hypersensitivity in a patient with an HLA-B*4601 allele

open access: yesNeuropsychiatric Disease and Treatment, 2018
Kumi Sakurada,1,* Takeshi Kozaru,2,* Kazuo Yamada,1 Masashi Nibuya,1 Kiyoshi Nagata,3 Eiji Suzuki1 1Department of Psychiatry, 2Department of Dermatology, 3Department of Environmental and Health Science, Tohoku Medical and Pharmaceutical University ...
Sakurada K   +5 more
doaj  

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