Results 111 to 120 of about 36,001 (235)
Advanced Science, Volume 13, Issue 55, 5 October 2026.This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen +14 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 10, October 2026.ABSTRACT Low phospholipid‐associated cholelithiasis (LPAC) syndrome is a rare inherited disorder caused by ABCB4 mutations with heterogeneous manifestations. We describe two LPAC cases in a mother–son pair, detailing their clinical presentations, diagnostic evaluations, and management. A novel ABCB4 frameshift variant (c.715_716insTT; p.Ser239PhefsTer9)
Hui‐Ming Yang, Jun Liu, Zheng Zhang
wiley +1 more source
General Psychiatry, Volume 39, Issue 5, October 2026.ABSTRACT Background Negative symptoms are a core diagnostic domain of schizophrenia that affect functional outcomes and remain difficult to treat. Agomelatine, a novel antidepressant with melatonin receptor agonism and serotonin 2C receptor antagonism, may have therapeutic potential.
Wanyan Zhou +22 more
wiley +1 more source
General Psychiatry, Volume 39, Issue 5, October 2026.ABSTRACT Background Heterogeneity in schizophrenia (SCZ) remains a major obstacle to the development of effective treatment. Aims This study aimed to identify reproducible neurobiological subtypes of SCZ using source‐localised, high‐density resting‐state electroencephalography (EEG) functional connectivity patterns.
Yue Ding +7 more
wiley +1 more source
Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 4, December 2026.
Norio Yasui‐Furukori
wiley +1 more source
Hepatocellular Carcinoma Targeted Thermosensitive Cu2+ Liposomes Based on the Cuproptosis Mechanism
MedComm, Volume 7, Issue 10, October 2026.This study develops galactose‐modified thermosensitive liposomes loaded with copper ions for the treatment of hepatocellular carcinoma. Combined with local tumor hyperthermia, this system delivers copper ions into tumor cells, induces cuproptosis by regulating FDX1 and DLAT expression and disrupting ROS/NADPH homeostasis, and suppresses tumor ...
Hao Yang +10 more
wiley +1 more source
Pharmacoepidemiology and Drug Safety, Volume 35, Issue 10, October 2026.ABSTRACT Purpose This study aims to assess the risk of metabolic side effects among paediatric new users of antipsychotics in Sweden, focusing on differences between substances and sexes. Methods Children aged 5–17 years, who were new users of antipsychotics between 2014 and 2021, were identified using Swedish national health registers.
Elin Eyfells Kimland +4 more
wiley +1 more source
Impact of Positively Charged Backbone Modifications on the Properties of Spherical Nucleic Acids
Small, Volume 22, Issue 55, 1 October 2026.A synthesis of spherical nucleic acids (SNAs) featuring cationic backbone modifications is presented, together with an analysis of their emerging properties. Introducing positively charged guanidinium groups near the SNA surface enhances cellular uptake and offers a pathway toward more precise control over SNA internalization.
Katherine E. Bujold +4 more
wiley +1 more source
Small Science, Volume 6, Issue 10, October 2026.Conductive high‐density poly(ethylene) (HDPE) is introduced as a new material platform for additive manufacturing electrochemistry, expanding the limited polymer feedstocks currently available. A solvent‐free thermal compounding process incorporating 40 wt% carbon black produced a flexible, plasticizer‐free filament with a low bulk resistivity of 16.4 (
Muhzamil A. Khan +9 more
wiley +1 more source
Frontiers in Cellular NeuroscienceIntroductionLoss of proteasome function, proteinopathy, and proteotoxicity may cause neurodegeneration across the human lifespan in several forms of brain injury and disease.
Adriana Amrein Almira +9 more
doaj +1 more source