Results 121 to 130 of about 36,001 (235)

Muscarinic agonists for schizophrenia: Bridging preclinical evidence and clinical enthusiasm

British Journal of Pharmacology, Volume 183, Issue 19, Page 5701-5731, October 2026.
Abstract Antipsychotic drugs targeting dopamine receptors have been used to treat schizophrenia for decades, primarily alleviating positive symptoms such as hallucinations and delusions. However, they provide limited benefit for cognitive and negative symptoms—major contributors to poor outcomes—and are frequently associated with significant side ...
Brian J. Morris, Judith A. Pratt
wiley   +1 more source

Effects of chlorpromazine on mammary glands of rats

, 1960
The effects of chlorpromazine were determined on mammary growth and initiation of milk secretion in virgin rats, and on maintenance of mammary structure and secretion in postpartum rats after litter removal. When chlorpromazine was administered in doses
P. K. Talwalker, C. S. Nicoll, J. Meites, T. F. Hopkins   +3 more
core   +1 more source

A Zeolitic Pyrimidine Framework (ZPF) Nanoplatform Co‐Delivers a DNAzyme and a Protein Prodrug for Cascade‐Activated Tumour Therapy

Cell Proliferation, Volume 59, Issue 10, October 2026.
A zeolitic framework co‐delivers a DNAzyme and a protein prodrug to tumour cells and executes a self‐amplifying therapeutic cascade: the DNAzyme elevates tumour oxidative stress to activate a caged RNase A prodrug. This spatiotemporally controlled synergy converts a genetic input into potent enzymatic cytotoxicity, suppressing tumour growth.
Yan Huang, Xingjie Hu, Jinli Sun, Min Yin, Nan Chen   +4 more
wiley   +1 more source

Factors influencing baseline electrocardiographic parameters in rats: A systematic review of experimental studies published from 1960 to the present

Physiological Reports, Volume 14, Issue 19, October 2026.
Abstract Experimental studies in rats use baseline or control values as a reference against which changes after experimental interventions are assessed. However, baseline or control ECG parameters may already be influenced by several factors before the experiment begins, complicating interpretation of the results.
Viktória Novotná, Soňa Grešová, Pavol Švorc   +2 more
wiley   +1 more source

Chlorpromazine reduces avoidance performance deficit in rats with dorsomedial thalamic lesions

, 2023
Rats with bilateral lesions of the dorsomedial area of the thalamus were shown to have a significant performance deficit on the acquisition of a one-way active shock-avoidance task relative to sham-operated controls.
Wuensch, Karl L., Means, Larry W., NC DOCKS at East Carolina University   +2 more
core  

Chlorpromazine

International Journal of Clinical Practice, 1956
openaire   +4 more sources

Chlorpromazine in Tetanus [PDF]

BMJ, 1961
openaire   +2 more sources

Chlorpromazine induced ocular myasthenia gravis [PDF]

, 2017
Drug induced bilateral ptosis is a very rare adverse drug reaction. Here we report a case of ten year old male child with chlorpromazine induced bilateral ptosis due to ocular ...
S, Nitya, R, Meher Ali, A, Mangaiarkkarasi, A, Jagadeesh, P, Deepa Kameswari   +4 more
core  

Prevalence of polypharmacy and factors impacting psychotropic prescribing patterns in women of childbearing potential at inpatient mental health services in Qatar

Neuropsychopharmacology Reports
Aims Women may experience unique mental disorders due to hormone shifts. Rates of schizophrenia and bipolar disorder are similar between genders, but onset and symptoms may differ.
Nervana Elbakary, Oraib Abdallah, Sami Ouanes, Ahmad Hasanoglu, Eiman Abedlfattah‐Arafa, Maha Al‐Shaikhly, Shatha Alqam, Sulaiman Alshakhs, Zainab Hijawi, Majid Al‐Abdulla, Noriya Al‐Khuzaei, Sazgar Hamad   +11 more
doaj   +1 more source

Determination of Residual N ‐Nitroso Desmethyl Chlorpromazine in Chlorpromazine HCl Injection by Liquid Chromatography–Tandem Mass Spectrometry

A selective, robust, and sensitive liquid chromatography–tandem mass spectrometry analytical procedure was developed to monitor trace amounts of potentially carcinogenic N ‑nitroso desmethyl chlorpromazine (NNO‑DM ...
Bhupinder Kumar, Dama Venugopala Rao, Raju Mudhulkar   +2 more
core   +1 more source