Results 41 to 50 of about 10,980 (183)

Cytotoxicity of 19 Pesticides in Rainbow Trout Gill, Liver, and Intestinal Cell Lines

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract The rainbow trout gill cell line (RTgill‐W1), via test guideline 249 of the Organisation for Economic Co‐operation and Development, has been established as a promising New Approach Methodology, although to advance confidence in the method more case studies are needed that: 1) expand our understanding of applicability domains (chemicals with ...
Sophie Emberley‐Korkmaz   +4 more
wiley   +1 more source

Purification and characterization of a novel chlorpyrifos hydrolase from Cladosporium cladosporioides Hu-01. [PDF]

open access: yesPLoS ONE, 2012
Chlorpyrifos is of great environmental concern due to its widespread use in the past several decades and its potential toxic effects on human health. Thus, the degradation study of chlorpyrifos has become increasing important in recent years.
Yan Gao   +5 more
doaj   +1 more source

Bioactivation of chlorpyrifos by CYP2B6 variants [PDF]

open access: yesXenobiotica, 2012
Chlorpyrifos (CPF), an organophosphorus (OP) pesticide, is bioactivated by cytochrome P450s (CYPs) to the active metabolite chlorpyrifos oxon (CPF-O). Given that human CYP2B6 has the highest intrinsic clearance (CL(int)) for CPF bioactivation, CYP2B6 polymorphisms may impact human susceptibility to CPF at real world environmental and occupational CPF ...
Alice L, Crane   +2 more
openaire   +2 more sources

Synergistic transition from type‐I‐like to type‐II‐like symptomology in a pyrethroid mixture and its impact on knockdown–mortality relationships in Musca domestica L

open access: yesPest Management Science, EarlyView.
In the present study, relationship between knockdown and mortality of insecticides was examined against the adult female housefly, Musca domestica. Type‐I pyrethroid insecticides showed a weak linkage, as early knocked down flies did not always result in mortality, while type‐II pyrethroids and organophosphates exhibited strong correlation between the ...
Junho Yoon, Jun‐Hyung Tak
wiley   +1 more source

Safety of Safety Evaluation of Pesticides: developmental neurotoxicity of chlorpyrifos and chlorpyrifos-methyl [PDF]

open access: yesEnvironmental Health, 2018
Authorization of pesticides for market release requires toxicity testing on animals, typically performed by test laboratories on contract with the pesticide producer. The latter provides the results and summary to the regulatory authorities. For the commonly used pesticide chlorpyrifos, an industry-funded toxicity study concludes that no selective ...
Axel Mie   +2 more
openaire   +5 more sources

Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa   +9 more
wiley   +1 more source

Changes in motor behavior and lumbar motoneuron morphology following repeated chlorpyrifos exposure in rats.

open access: yesPLoS ONE
Chlorpyrifos is an organophosphate pesticide associated with numerous health effects including motor performance decrements. While many studies have focused on the health effects following acute chlorpyrifos poisonings, almost no studies have examined ...
Shannon H Romer   +5 more
doaj   +1 more source

Enzymatic degradation of extracellular DNA exposed to chlorpyrifos and chlorpyrifos-methyl in an aqueous system

open access: yesEnvironment International, 2019
The persistence of extracellular DNA (eDNA) is crucial for ensuring species diversity and ecological function in aquatic systems. However, scarce information exists about the impact of pesticides on eDNA, although they often co-exist in the aquatic ...
Bing Yang   +7 more
doaj   +1 more source

Chlorpyrifos Toxicosis in Two Cats [PDF]

open access: yesJournal of Veterinary Internal Medicine, 1990
Abstarct Organophosphate compounds are widely employed for control of external parasites in cats and for control of insects in homes and yards. Chlorpyrifos is a long-acting organophosphate (OP) available for use as a systemically and topically acting parasiticide and insecticide in cattle.
A, Jaggy, J E, Oliver
openaire   +2 more sources

Oxidative Damage, Energy Imbalance, and Behavioral Disruptions in Girardia tigrina Exposed to Treated Sewage Effluents

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT This study assessed the ecotoxicological effects of treated sewage on the freshwater planarian Girardia tigrina, integrating biochemical, energetic, and behavioral biomarkers. Planarians were exposed for 48 h to different concentrations of treated sewage (12.5%, 25%, 50%, and 100%) and compared to controls using commercial water and water from
Renata M. P. Freitas   +3 more
wiley   +1 more source

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