Synthesis of Bioactive Aminomethylated 8-Hydroxyquinolines via the Modified Mannich Reaction. [PDF]
Int J Mol Sci, 2023 8-hydroxyquinoline (oxine) is a widely known and frequently used chelating agent, and the pharmacological effects of the core molecule and its derivatives have been studied since the 19th century.
Csuvik O, Szatmári I.
europepmc +3 more sources
Applied Sciences, 2023 The incidence of superficial infections, including oral candidiasis, has recently increased significantly. Their treatment is quite difficult due to the growing resistance of Candida spp. to antifungal agents.
Anna Biernasiuk, Anna Malm
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Exploring multielement nanogranular coatings to forestall implant-related infections [PDF]
, 2023 Introduction: As we approach the post-antibiotic era, the development of innovative antimicrobial strategies that carry out their activities through non-specific mechanisms could limit the onset and spread of drug resistance.
Balzano, Vincenzo +7 more
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A Simple Procedure for Synthesis of Biological Active 4-oxo-4-(quinolin-8-yloxy)but-2-enoic acid [PDF]
, 2022 The article is devoted to research on the synthesis of hydroxyquinoline derivative based on 8-oxyquinoline and maleic anhydride. Analysis of available literature was carried out, some drugs were found that are produced based on hydroxyquinoline ...
A.I. Almazov +4 more
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Installing the "magic methyl"- C-H methylation in synthesis [PDF]
, 2021 The selective and efficient C-H methylation of sp2 and sp3 carbon centres has become a powerful transformation in the synthetic toolbox. Due to the potential for profound changes to physicochemical properties attributed to the installation of a "Magic ...
Aynetdinova, Daniya +8 more
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COMPETENCE OF THE STUDENTS FROM THE MEDICAL UNIVERSITY OF VARNA FOR PRESCRIBING A RATIONAL PHARMACOTHERAPY [PDF]
, 2017 The skills of the students from the iMedical University of Varna for choosing and prescribing of a rational pharmacotherapy were tested. This took place within the framework of a comparative study of the competence in the therapeutic skills of final year
Belcheva, A.
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, 2009 The two symmetry independent mol-ecules of the title compound, C 19H13Cl2NO4, show similar conformations with the acetyl group twisted strongly relative to the remaining, virtually flat (r.m.s.
Łukasz Ponikiewski +9 more
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Antiseptics and disinfectants for the treatment of bacterial vaginosis: a systematic review [PDF]
, 2012 Background: The study objective was to assess the available data on efficacy and tolerability of antiseptics and disinfectants in treating bacterial vaginosis (BV). Methods: A systematic search was conducted by consulting PubMed (1966-2010), CINAHL (1982-
A Cardone +27 more
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Repurposing FDA approved drugs against the human fungal pathogen, Candida albicans. [PDF]
Ann Clin Microbiol Antimicrob, 2015 BACKGROUND: The high cost and prolonged timeline of new drug discovery and development are major roadblocks to creating therapies for infectious diseases.
Kim K, Zilbermintz L, Martchenko M.
europepmc +3 more sources
Studi Literatur Aktivitas Antibakteri Ekstrak Biji Jintan Hitam (Nigella sativa L.) terhadap Beberapa Bakteri Patogen [PDF]
, 2021 Resistensi bakteri terhadap antibiotik masih menjadi masalah global yang serius, dibutuhkan beberapa upaya untuk mengurangi masalah tersebut, salah satunya yaitu penemuan senyawa obat baru yang berasal dari bahan alam.
Afifah, Kharisah
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