Results 91 to 100 of about 4,532 (203)

Benefits and side effects of blood pressure lowering treatment: what was wrong with doxazosin in the ALLHAT?

open access: yesCurrent Controlled Trials in Cardiovascular Medicine, 2001
The lowering of high blood pressure is supposed to protect target organs from hypertensive damage. The Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial was designed to compare the cardioprotective properties of three ...
Gavras Haralambos, Gavras Irene
doaj   +1 more source

The combination of chlorthalidone with nifedipine does not exert an additive antihypertensive effect in essential hypertensives: a crossover multicenter study.

open access: yes, 1991
To evaluate whether the combination of nifedipine with chlorthalidone exerts an additive antihypertensive effect when compared to single-drug treatment, 66 uncomplicated essential hypertensives, whose diastolic blood pressure was greater than 100 and ...
Ballestra AM   +10 more
core  

VALIDATED CHIRAL RP-UFLC METHOD FOR THE QUANTIFICATION OF CHLORTHALIDONE IN BULK AND PHARMACEUTICAL DOSAGE FORM [PDF]

open access: yes, 2017
Objective: Development and validation of new, simple and reliable enantioselective reverse phase ultra-fast liquid chromatography (RP-UFLC) method for quantification of chlorthalidone in bulk and pharmaceutical dosage form.Methods: In the present study ...
Gurupadayya, Bannimath, Choezom, Tenzin
core   +1 more source

DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR AMLODIPINE, CHLORTHALIDONE AND OLMESARTAN IN SOLID DOSAGE FORM

open access: yes, 2017
To develop and validate simple and rapid isocratic reversed-phase high-performance liquid chromatography method (RP-HPLC) for the simultaneous estimation of Amlodipine , Chlorthalidone and Olmesartan in synthetic mixture.
Hinal B. Patel*, D.P. Damahe, S.B. Narkhede
core   +1 more source

Development and Validation of Stability Indicating UPLC Method for Simultaneous Determination of Olmesartan Medoxomil and Chlorthalidone in Bulk and Pharmaceutical Dosage Form [PDF]

open access: yes
Aim: The establishment and validation of simultaneous determination of Olmesartan medoxomil and chlorthalidone by UPLC according to ICH guidelines ensure that the analytical method meets regulatory standards and can be used effectively for quantitative ...
Lavanya. K, Chaithanya Sudha. P. D, M. K. Ranganath, Ramesh G, Kavitha
core   +1 more source

Comparison of Cardiovascular Outcomes Between Chlorthalidone and Hydrochlorothiazide in Hypertensive Patients

open access: yesThe Journal of Clinical Hypertension
Chlorthalidone (CLTD) and hydrochlorothiazide (HCTZ) are widely used thiazide diuretics for hypertension management. This study aimed to evaluate and compare the cardiovascular outcomes of patients treated with CLTD versus HCTZ.
Subin Lim   +7 more
doaj   +1 more source

Development and Validation of RP- HPLC Method for Simultaneous Estimation of Telmisartan and Chlorthalidone in Pharmaceutical Dosage Form

open access: yes
Telmisartan and Chlorthalidone in bulk and combined dosage form were analysed and validated using RP-HPLC. A new technique was developed for the simultaneous estimation of this to medications using this method.
G. Bhavana   +4 more
core   +1 more source

Metabolic effects of long-term therapy with muzolimine and chlorthalidone in hypertension.

open access: yes, 1987
Previous short-term studies of muzolimine (a diuretic with frusemide-like activity) had shown that it did not induce a significant change in the serum potassium concentration.
R. Gagliardi   +6 more
core  

Quality Assessment of medication containing chlorthalidone [PDF]

open access: yes, 2017
Diuretics are the most used class of drugs that are used to treat hypertension because of their therapeutic efficiency and low cost. This makes a wide variety of medicines commercially available and, linked to this factor, many companies have their ...
Juliana de Oliveira Alves   +5 more
core  

Development and validation of reversed phase gradient HPLC method for the simultaneous estimation of olmesartan medoxomil and chlorthalidone in dosage forms

open access: yes, 2020
The main objective of the proposed study is to develop and validate a new stability indicating reverse phase HPLC gradient method for the simultaneous estimation of olmesartan medoxomil and chlorthalidone in combined dosage form.
S Manikandan, G Thirunarayanan
core  

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