Results 261 to 270 of about 2,200,065 (287)

Universal Antibody‐Engineered Lipid Nanoparticles Potentiate Chemo‐Immunotherapy Against Triple‐Negative Breast Cancer by Reprogramming Tumor Cell Metabolism

Advanced Science, EarlyView.
A universal ROR1 antibody‐engineered lipid nanoparticle (LNP) is constructed by sequential drug encapsulation and antibody conjugation. The LNP not only enables enhanced chemotherapeutic efficiency by targeting drug delivery and precise localization of deep‐seated tumors through NIR‐II fluorescence imaging, but also remodels immunosuppressive TME ...
Yeneng Dai, Jiaqi Wang, Yu Liu, Guanda Jiao, Yuheng Gu, Yang Liu, Shengyu Fu, Xing Fan, Jialin Li, Ziang Guo, Kam Tong Leung, Lipeng Zhu, Qi Zhao   +12 more
wiley   +1 more source

Elucidation of Proteoforms of Chinese Hamster Ovary (CHO) Phospholipase B-Like 2 (PLBL2) Captured From a Monoclonal Antibody. [PDF]

Biotechnol Bioeng
Dolan ME, Wang LL, Tedeschi A, Wang Y, Barton C, Oppenheim SF, Zhou ZS.   +6 more
europepmc   +1 more source

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

Advanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao, Qingzhou Kong, Haifan Gong, Lixiang Li, Jialu Fu, Boyao Wan, Peizhu Wang, Xiaojuan Li, Yue Wang, Jinghui Zhang, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +14 more
wiley   +1 more source

Correction: Deep-learning-based gas identification by time-variant illumination of a single micro-LED-embedded gas sensor. [PDF]

Light Sci Appl
Cho I, Lee K, Sim YC, Jeong JS, Cho M, Jung H, Kang M, Cho YH, Ha SC, Yoon KJ, Park I.   +10 more
europepmc   +1 more source

Programmable Pentamolecular Cross‐Scale Imaging Reveals the Multiplicative Synergistic Effect of High‐Fat / High‐Salt Diet on Atherosclerosis

Advanced Science, EarlyView.
This study demonstrates multifactorial lifestyle impacts on the pathogenesis and progression of cardiovascular diseases by a nanofluorescence sensor array for detecting four redox species and protein phosphorylation levels. Through cross‐scale fluorescence imaging of rats with different diets, we revealed that compared with single dietary interventions,
Jin Li, Na Zhao, Mengmeng Lu, Ruize Zhao, Wei Zhang, Ping Li, Yue Tang, Wen Zhang, Hui Wang, Bo Tang   +9 more
wiley   +1 more source

Thrombomodulin is essential for recombinant Fc-fusion protein production in Chinese hamster ovary cells via multiple signaling pathways. [PDF]

J Biol Eng
Ma X, Wang N, Yan Q, Li S, Hu G, Zhao L, Xiao R, Wang M, Ma N.   +8 more
europepmc   +1 more source

Large Anomalous Hall Effect, Non‐Vanishing Berry Curvature in (110) FeRh Antiferromagnet Films via Interface Strain

Advanced Science, EarlyView.
This study demonstrates a strain‐tunable anomalous Hall response in the (110)‐oriented FeRh thin film. First‐principles calculations reveal that strain‐induced symmetry lowering redistributes Berry curvature near the Fermi level via band shifts and avoided crossings.
Yun‐Ho Kim, Gil‐Sung Kim, Jae Won Choi, Jung‐Min Cho, Won‐Yong Lee, Hongkee Yoon, Yeonho Choi, Shelby Fields, Steven Bennett, Mona Zebarjadi, Young‐Gui Yoon, Sang‐Kwon Lee   +11 more
wiley   +1 more source

Under Consumed and Overestimated: Discrepancies in Race-Day Carbohydrate Intake Among Endurance Athletes. [PDF]

Eur J Sport Sci
Lanpir AD, Eroğlu MN, Özyıldırım M, Louis J.   +3 more
europepmc   +1 more source

Small and Simple Molecular Structure Based Thermally Stable Ruthenium Precursor in Advancing Ruthenium ALD Process for Scaled Interconnect Metallization

Advanced Science, EarlyView.
A thermally robust (≈400 °C), critically small‐size‐simple ligand structure ruthenium (Ru) precursor enables exceptional growth per cycle (≈1.28 Å cycle−1), short incubation (≈8 cycles), ultralow resistivity (8.65 µΩ cm) and outstanding substrate selectivity via atomic layer deposition (ALD) process at high temperatures, overcoming prior Ru‐ALD ...
Hideaki Nakatsubo, Debananda Mohapatra, Eun‐Soo Lee, Jeongha Kim, Iaan Cho, Masato Iseki, Toshiyuki Shigetomi, Ryosuke Harada, Sang‐Woong Na, Taehoon Cheon, Bonggeun Shong, Soo‐Hyun Kim   +11 more
wiley   +1 more source

Systematic Evaluation of Vector Sequence Elements in Isogenic CHO Cells for Improved Antibody Production. [PDF]

ACS Synth Biol
Rahimi M, Adams AC, Grav LM, Nielsen LK, Lavado-García J.   +4 more
europepmc   +1 more source