Kindlin Regulates Mechanosensitive Activation and Adhesion Assembly of Integrin beta6
Extracellular matrix compliance plays a critical role in the regulation of integrin‐mediated adhesion and cell motility. Here, it is reported that strengthening the kindlin2‐integrin β6 interaction overcomes the dependence on extracellular substrate stiffness and promotes integrin β6‐mediated cell migration.
Wan Ning Lee+3 more
wiley +1 more source
Generating and characterizing a comprehensive panel of CHO cells glycosylation mutants for advancing glycobiology and biotechnology research. [PDF]
Haryadi R+9 more
europepmc +1 more source
A Ku80 fragment with dominant negative activity imparts a radiosensitive phenotype to CHO-K1 cells [PDF]
Elisabetta Marangoni
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The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang+15 more
wiley +1 more source
A Flexible Hybrid Site-Specific Integration-Based Expression System in CHO Cells for Higher-Throughput Evaluation of Monoclonal Antibody Expression Cassettes. [PDF]
Szkodny AC, Lee KH.
europepmc +1 more source
Ultrastructure and reproduction behaviour of single CHO‐K1 cells exposed to near infrared femtosecond laser pulses [PDF]
H Oehring+4 more
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Introducing energetic Cu‐based metal salts into the covalent organic frameworks (COFs) structure, Cu is in single‐atom form anchored to the framework, with energetic anions confined in the COFs structure. The synergistic interaction between single Cu atoms and the anions accelerates the reaction kinetics of ammonium perchlorate (AP) decomposition ...
Meng Zhang+8 more
wiley +1 more source
Sequence and Configuration of a Novel Bispecific Antibody Format Impacts Its Production Using Chinese Hamster Ovary (CHO) Cells. [PDF]
Hussain H+11 more
europepmc +1 more source
Expression of an Anti-CD3 Single-Chain Immunotoxin with a Truncated Diphtheria Toxin in a Mutant CHO Cell Line [PDF]
Yuan Yi Liu+6 more
openalex +1 more source