Results 231 to 240 of about 228,451 (311)

Cell Segmentation Beyond 2D—A Review of the State‐of‐the‐Art

Advanced Intelligent Discovery, EarlyView.
Cell segmentation underpins many biological image analysis tasks, yet most deep learning methods remain limited to 2D despite the inherently 3D nature of cellular processes. This review surveys segmentation approaches beyond 2D, comparing 2.5D and fully 3D methods, analyzing 31 models and 32 volumetric datasets, and introducing a unified reference ...
Fabian Schmeisser, Haseeb Muhammad, Junaid Younas, Gillian Lovell, Bianca Migliori, Andreas Dengel, Sheraz Ahmed   +6 more
wiley   +1 more source

Large-scale transcriptomics analysis reveals a novel stress biomarker in CHO cells producing difficult to express mAbs. [PDF]

Sci Rep
Papadaki S, Tournaviti S, Borth N, Großkopf T, Popp O, Chung SH, Quaiser T.   +6 more
europepmc   +1 more source

Uncertainty‐Guided Selective Adaptation Enables Cross‐Platform Predictive Fluorescence Microscopy

Advanced Intelligent Discovery, EarlyView.
Deep learning models often fail when transferred to new microscopes. A novel framework overcomes this by selectively adapting the early layers governing low‐level image statistics, while freezing deep layers that encode morphology. This uncertainty‐guided approach enables robust, label‐free virtual staining across diverse systems, democratizing ...
Kai‐Wen K. Yang, Andrew Bai, Alexandra Bermudez, Yunqi Hong, Zoe Latham, Iris Sloan, Michael Liu, Vishrut Goyal, Cho‐Jui Hsieh, Neil Y. C. Lin   +9 more
wiley   +1 more source

A novel dual-epigenetic inhibitor enhances recombinant monoclonal antibody expression in CHO cells. [PDF]

Appl Microbiol Biotechnol
Han MM, Wang HT, Zhang HJ, Lu JT, Guo JL, Qiu LL, Zhang X, Wang XY, Wang TY, Jia YL.   +9 more
europepmc   +1 more source

A Memristor‐Based In‐Memory Computing System‐on‐Chip with Efficient Depthwise Convolution

Advanced Intelligent Systems, EarlyView.
We present a memristor‐based in‐memory computing (IMC) architecture that enables efficient depthwise convolution (DWC) acceleration. Fabricated in a system‐on‐chip with crossbar arrays, the design improves memory utilization. Experimental validation demonstrates the first hardware acceleration of DWC in IMC, achieving a digital comparable inference ...
Wenhao Song, Fuxi Cai, Sangsu Park, Zhaoyan Li, Seonghun Lee, Mingyi Rao, Woohyung Choi, Seungin Shin, Yan Zhu, Sujin Chae, Myoungsub Kim, Mingche Wu, Hyejung Choi, Yuan Dao, Jaeyun Yi, Youngman Cho, Seon Yong Cha, Ning Ge, Qiangfei Xia, Soo Gil Kim, Miao Hu, J. Joshua Yang   +21 more
wiley   +1 more source

Generating and characterizing a comprehensive panel of CHO cells glycosylation mutants for advancing glycobiology and biotechnology research. [PDF]

Sci Rep
Haryadi R, Chan KF, Lin PC, Tan YL, Wan C, Shahreel W, Tay SJ, Nguyen-Khuong T, Walsh I, Song Z.   +9 more
europepmc   +1 more source

Taxonomic reassessment of fossil Sequoia and Protosequoia from the Upper Miocene of Central Honshu, Japan, with implications for leaf morphological variation in extant S. sempervirens

American Journal of Botany, EarlyView.
Abstract Premise Since its emergence in the Mesozoic, Sequoia (Cupressaceae) has been considered to possess conserved leaf morphology. However, recent studies have shown that the leaves of extant S. sempervirens become smaller, with a scale form, with increasing tree height.
Shun Ikeda, Arata Momohara
wiley   +1 more source

Engineering of the Caspase-3 Gene in Recombinant CHO Cells Caused More Apoptosis Resistance and enhanced Recombinant Protein Production Than the BAX Gene. [PDF]

Iran Biomed J
Rahimi A, Karimipoor M, Mahdian R, Alipour A, Hosseini S, Mohammadi M, Kaghazian H, Shahsavarani H, Shokrgozar MA.   +8 more
europepmc   +1 more source

Hidden in the Labour Market: An Intersectional Latent Class Analysis of Discouraged Workers in Australia

Australian Journal of Social Issues, EarlyView.
ABSTRACT This study employs an intersectionality‐informed latent class analysis (LCA) to examine the hidden diversity of discouraged workers in Australia. Drawing on nationally representative data from the Household, Income and Labour Dynamics in Australia Survey, we identified six empirically distinct subgroups defined by intersecting demographic and ...
Sora Lee, Woojin Kang
wiley   +1 more source

Increased glycoprotein hormone yield in stably transfected CHO cells using human serum albumin signal peptide for beta-chains. [PDF]

PeerJ
Sinegubova MV, Kolesov DE, Vorobiev II, Orlova NA.   +3 more
europepmc   +1 more source