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ambr® 15 Microbioreactors for CHO Cell Cultivation

2019
The ambr 15 has become the industry's standard automated microbioreactor system for mammalian cell culture. It has applications throughout the industry, most commonly for cell line screening and media/feed development. On each ambr 15 workstation, conditions in up to 48 × 15 mL bioreactors can be individually controlled while a liquid handler enables ...
openaire   +2 more sources

A Single‐Cell Model for CHO Cellsa

Annals of the New York Academy of Sciences, 1992
P, Wu, N G, Ray, M L, Shuler
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Microsome-mediated cytotoxicity to CHO cells

Mutation Research Letters, 1982
E L, Tan, R L, Schenley, A W, Hsie
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CHO Cell Antibody Drug Production

Therapeutic antibodies are highly regarded for their high affinity, specificity, low immunogenicity, and ability to target a wide range of biological molecules. Currently, mammalian cells, including Sp2/0, NS0, HEK293, and CHO cells, are primarily used for the production of therapeutic antibodies, with CHO cells accounting for over 70% of the ...
openaire   +1 more source

Recombinant Protein Production from Stable CHO Cell Pools

The continuous improvement of expression platforms is necessary to respond to the increasing demand for recombinant proteins that are required to carry out structural or functional studies as well as for their characterization as biotherapeutics. While transient gene expression (TGE) in mammalian cells constitutes a rapid and well-established approach,
Delafosse, Laurence   +9 more
openaire   +3 more sources

Integrative analysis of DNA methylation and gene expression in butyrate-treated CHO cells.

Journal of Biotechnology, 2017
Anna Wippermann   +4 more
semanticscholar   +1 more source

Glycoengineering of CHO Cells to Improve Product Quality.

Methods in molecular biology, 2017
Qiong Wang   +3 more
semanticscholar   +1 more source

Inactivation of GDP‐fucose transporter gene (Slc35c1) in CHO cells by ZFNs, TALENs and CRISPR‐Cas9 for production of fucose‐free antibodies

Biotechnology Journal, 2016
Kah Fai Chan   +10 more
semanticscholar   +1 more source

Targeted Gene Deletion Using DNA-Free RNA-Guided Cas9 Nuclease Accelerates Adaptation of CHO Cells to Suspension Culture.

ACS Synthetic Biology, 2016
Namil Lee   +5 more
semanticscholar   +1 more source

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