Results 221 to 230 of about 188,771 (295)

Progastrin Promotes Colorectal Cancer Stem Cell‐Like Properties via the Receptor PZR

Advanced Science, EarlyView.
The tumor microenvironment supports colorectal cancer (CRC) progression by maintaining cancer stem cells (CSCs) through progastrin (PG). This study identifies Protein Zero‐Related protein (PZR) as an essential receptor for PG activity, promoting CSC‐like signaling via SHP2/SRC/β‐catenin.
Julie Nguyen, Marie Lafitte, Maud Barbery, Kevin Espie, Maya Jeitany, Romain Larive, Jihane Vitre, Conception Paul, Yvan Boublik, Elise Fourgous, Valérie Simon, Audrey Sirvent, Madeline Neiveyans, Steeve Thirard, Lucile Bansard, Morgan Maillard, Nathalie Coutry, Jacques Colinge, Philippe Jay, Pierre Martineau, Michael Hahne, Julie Pannequin, Serge Roche   +22 more
wiley   +1 more source

Cytogenetic genotoxicity of anti-herpes purine nucleoside analogues in CHO cells expressing the thymidine kinase gene of herpes simplex virus type 1: comparison of ganciclovir, penciclovir and aciclovir [PDF]

, 2000
R Thust, Maja Tomičić, R. Klöcking, P Wutzler, Bernd Kaina   +4 more
openalex   +1 more source

Attenuated Nuclear Tension Regulates Progerin‐Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling

Advanced Science, EarlyView.
The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park, Juhyeon Jo, Kun Xu, Sun‐Ah Lee, Seong‐Beom Han, YigJi Lee, Won‐Ki Cho, Bo Li, Soo Hyun Kim, Dong‐Hwee Kim   +9 more
wiley   +1 more source

Recombinant therapeutic proteins degradation and overcoming strategies in CHO cells. [PDF]

Appl Microbiol Biotechnol
Geng SL, Zhao XJ, Zhang X, Zhang JH, Mi CL, Wang TY.   +5 more
europepmc   +1 more source

Structural requirements of muramylpeptides for induction of Toll-like receptor 2-mediated NF-κB activation in CHO cells [PDF]

, 2000
Atsutoshi Yoshimura, Haruhiko Takada, Takashi Kaneko, Ihachi Kato, Douglas T. Golenbock, Yoshitaka Hara   +5 more
openalex   +1 more source

Refractive Index‐Corrected Light‐Sheet Microscopy for Macro‐View Cardiovascular Imaging

Advanced Science, EarlyView.
A refractive index‐corrected light‐sheet fluorescence microscopy system enables macro‐view cardiovascular imaging across organs, adapting to refractive index variations from different optical clearing protocols. By integrating axial sweeping, multi‐view imaging, and a sealed chamber, it extends the field of view, enhances isotropy, and improves safety.
Enbo Zhu, Yaran Zhang, Peng Zhao, Jae Min Cho, Zhaoqiang Wang, Yan‐Ruide Li, Jing Wang, Samuel Margolis, Shaolei Wang, Lili Yang, Alison Chu, Yuhua Zhang, Liang Gao, Tzung K. Hsiai   +13 more
wiley   +1 more source

Quantitative proteomics reveals cellular responses to individual mAb expression and tunicamycin in CHO cells. [PDF]

Appl Microbiol Biotechnol
Sulaj E, Schwaigerlehner L, Sandell FL, Dohm JC, Marzban G, Kunert R.   +5 more
europepmc   +1 more source

Productivity enhancement of recombinant protein in CHO cells via specific promoter activation by oncogenes.

, 1999
Yoshinori Katakura, Perry Seto, Takumi Miura, Hideya Ohashi, Kiichiro Teruya, Sanetaka Shirahata   +5 more
openalex   +2 more sources

Tuneable Hydrogel Porosity via Dynamic Tailoring of Spinodal Decomposition

Advanced Science, EarlyView.
The authors introduce a straightforward method for dynamically halting the phase separation of a gelatin methacryloyl and poly(vinyl alcohol) (GelMA‐PVA) polymer blend in the context of a biofabrication process based on dynamic interface printing (DIP).
Michael Halwes, Callum Vidler, Lilith Caballero Aguilar, Farzaneh Taromian, David R Nisbet, Melanie Stamp, Khoon S. Lim, Andrea J. O'Connor, David J. Collins   +8 more
wiley   +1 more source

Synthetic enhancers including TFREs improve transgene expression in CHO cells. [PDF]

Heliyon
Liu HN, Wang XY, Zou Y, Wu WB, Lin Y, Ji BY, Wang TY.   +6 more
europepmc   +1 more source