Results 291 to 300 of about 663,360 (333)

Enhancing Human Glycoprotein Hormones Production in CHO Cells Using Heterologous Beta-Chain Signal Peptides. [PDF]

open access: yesDokl Biochem Biophys
Sinegubova MV   +4 more
europepmc   +1 more source

A case of uveitis associated with novel corona-virus inactivated vaccine engineered CHO cells: A case report

open access: hybrid
Caihui Liu   +7 more
openalex   +1 more source

Chromosome stability in CHO cells

Somatic Cell Genetics, 1977
The established cell line derived many years ago from Chinese hamster ovary (CHO cells) has been studied for the extent of chromosomal variation. Because this cell line is used extensively for genetic studies, the contribution of chromosome variability to genetic variability has also been examined. The quasidiploid CHO cells were found to have a banded
R G, Worton, C C, Ho, C, Duff
openaire   +2 more sources

DNA methylation in CHO cells

Journal of Biotechnology, 2017
Chinese hamster ovary (CHO) cells account for the production of the majority of biopharmaceutical molecules - however, the molecular basis for their versatile properties is not entirely understood yet and the underlying cellular processes need to be characterized in detail.
Wippermann, Anna, Noll, Thomas
openaire   +2 more sources

Dynamic model of CHO cell metabolism

Metabolic Engineering, 2011
Fed-batch cultures are extensively used for the production of therapeutic proteins. However, process optimization is hampered by lack of quantitative models of mammalian cellular metabolism in these cultures. This paper presents a new kinetic model of CHO cell metabolism and a novel framework for simulating the dynamics of metabolic and biosynthetic ...
Ryan P, Nolan, Kyongbum, Lee
openaire   +2 more sources

Misonidazole-glutathione conjugates in CHO cells

International Journal of Radiation Oncology*Biology*Physics, 1984
Misonidazole, after reduction to the hydroxylamine derivative, reacts with glutathione (GSH) under physiological conditions. The reaction product has been identified as a mixture of two isomeric conjugates. When water soluble extracts of CHO cells exposed to misonidazole under hypoxic conditions are subjected to HPLC analysis, misonidazole derivatives,
A J, Varghese, G F, Whitmore
openaire   +2 more sources

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