Stress-induced increase of monoclonal antibody production in CHO cells. [PDF]
Schellenberg J+6 more
europepmc +1 more source
This work explores a machine learning (ML) model with electrochemical impedance spectroscopy (EIS) data to address two critical challenges in Lithium metal batteries (LMBs): capacity degradation trajectory and knee point (KP) estimation, for the first time.
Qianli Si+4 more
wiley +1 more source
Generating and characterizing a comprehensive panel of CHO cells glycosylation mutants for advancing glycobiology and biotechnology research. [PDF]
Haryadi R+9 more
europepmc +1 more source
Expression of an Anti-CD3 Single-Chain Immunotoxin with a Truncated Diphtheria Toxin in a Mutant CHO Cell Line [PDF]
Yuan Yi Liu+6 more
openalex +1 more source
CHO Cell Antibody Drug Production
Therapeutic antibodies are highly regarded for their high affinity, specificity, low immunogenicity, and ability to target a wide range of biological molecules. Currently, mammalian cells, including Sp2/0, NS0, HEK293, and CHO cells, are primarily used for the production of therapeutic antibodies, with CHO cells accounting for over 70% of the ...
openaire +2 more sources
The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park+9 more
wiley +1 more source
A Flexible Hybrid Site-Specific Integration-Based Expression System in CHO Cells for Higher-Throughput Evaluation of Monoclonal Antibody Expression Cassettes. [PDF]
Szkodny AC, Lee KH.
europepmc +1 more source
Influence of alterations in culture condition and changes in perfusion parameters on the retention performance of a 20 mum spinfilter during a perfusion cultivation of a recombinant CHO cell line in pilot scale. [PDF]
Kai Iding+4 more
openalex +1 more source
An amphiphilic open‐shell d/π‐conjugated nickel dithiolate salt forms a bilayer capsule exhibiting uniaxial magnetic anisotropy, driven by spin–spin interactions. The capsule, exceptionally stable in aqueous environments, undergoes temperature‐dependent structural transitions representing, to the knowledge, the first observation of such behavior for ...
Tomoko Fujino+13 more
wiley +1 more source