Results 61 to 70 of about 1,112,448 (278)
FastVentricle: Cardiac Segmentation with ENet
, 2017 Cardiac Magnetic Resonance (CMR) imaging is commonly used to assess cardiac structure and function. One disadvantage of CMR is that post-processing of exams is tedious. Without automation, precise assessment of cardiac function via CMR typically requires
A Suinesiaputra +9 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Ethical Choice Architecture in Preabortion Counseling [PDF]
AMA Journal of Ethics, 2020 Most women requesting pregnancy termination have already decided to undergo an abortion. Physicians are required to obtain informed consent after offering objective and accurate descriptions of abortion and its risks and benefits. Some jurisdictions also require concurrent counseling and ultrasound viewing. This article discusses potential benefits and
openaire +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
How to Nudge a Modern Consumer towards Healthier Food Choices
ProceedingsFood environments have a major influence on consumers’ food choices. The increasing abilities and accessibility of technology have caused food choices to be made in digital environments.
Eva Valenčič +4 more
doaj +1 more source
Atmosphere, 2018 Although the field has seen great advances in hurricane prediction and response, the economic toll from hurricanes on U.S. communities continues to rise.
Kerry Milch +3 more
doaj +1 more source
Design citeria for applications with non-manifest loops [PDF]
, 2004 In the design process of high-throughput applications, design choices concerning the type of processor architecture and appropriate scheduling mechanism, have to be made.
Krol, Thijs +2 more
core +1 more source
Encoding natural movement as an agent-based system: an investigation into human pedestrian behaviour in the built environment [PDF]
, 2002 Gibson's ecological theory of perception has received considerable attention within psychology literature, as well as in computer vision and robotics.
Penn, A, Turner, A
core +1 more source