Results 71 to 80 of about 1,108,283 (319)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
How to Nudge a Modern Consumer towards Healthier Food Choices
ProceedingsFood environments have a major influence on consumers’ food choices. The increasing abilities and accessibility of technology have caused food choices to be made in digital environments.
Eva Valenčič +4 more
doaj +1 more source
Atmosphere, 2018 Although the field has seen great advances in hurricane prediction and response, the economic toll from hurricanes on U.S. communities continues to rise.
Kerry Milch +3 more
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Apache Calcite: A Foundational Framework for Optimized Query Processing Over Heterogeneous Data Sources [PDF]
, 2018 Apache Calcite is a foundational software framework that provides query processing, optimization, and query language support to many popular open-source data processing systems such as Apache Hive, Apache Storm, Apache Flink, Druid, and MapD.
Begoli, Edmon +4 more
core +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Giving Science Innovation Systems a 'Nudge'
Technology Innovation Management Review, 2019 In this article we consider the role that contextual factors play in science innovation systems – that is, the choice architecture, that influences the orientation and outcomes of publicly-funded research.
Kirsty de Jong +4 more
doaj +1 more source
Design citeria for applications with non-manifest loops [PDF]
, 2004 In the design process of high-throughput applications, design choices concerning the type of processor architecture and appropriate scheduling mechanism, have to be made.
Krol, Thijs +2 more
core +1 more source
Design and User Satisfaction of Interactive Maps for Visually Impaired People [PDF]
, 2012 Multimodal interactive maps are a solution for presenting spatial information to visually impaired people. In this paper, we present an interactive multimodal map prototype that is based on a tactile paper map, a multi-touch screen and audio output.
A. Bangor +19 more
core +4 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source