Results 91 to 100 of about 17,265,580 (249)
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
, 2012 REACTION 2012. 1st International workshop on Real-time and distributed computing in emerging applications.
REACTION 2012
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Desperately seeking streaming: CHOICE digital consumers paying for content behaviour and attitudes
, 2015 Has the launch of new streaming services in Australia had an impact on the ways Australians access digital content or is a punitive regulatory approach necessary to reduce piracy?
Choice
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Autism Spectrum Disorder (ASD) is a neurodevelopmental behavioral disorder characterized by social, communicative, and motor deficits. There is no single etiological cause for ASD, rather, there are various genetic and environmental factors that increase
Melvin Maroon (18155547) +1 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Reaction time in a visual 4-choice reaction time task: ERP effects of motor preparation and hemispheric involvement [PDF]
, 2016 Reaction time (RT), the most common measure of CNS efficiency, shows intra- and inter-individual variability. This may be accounted for by hemispheric specialization, individual neuroanatomy, and transient functional fluctuations between trials.
Antonova, Ingrida +5 more
core +2 more sources
A ‘priming’ effect in a choice reaction time task
Acta Psychologica, 1988 Abstract Two experiments were conducted to determine the effect of a prior stimulus (prime) on reaction time to a target stimulus. The target was a red or green color patch to which subjects responded by pressing a red or green key. The prime was a red, green, or white color patch for one group and the word Red, Green, or White for another group. The
openaire +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Increased reaction times and reduced response preparation already starts at middle age
Frontiers in Aging Neuroscience, 2014 Generalized slowing characterizes aging and there is some evidence to suggest that this slowing already starts at midlife. This study aims to assess reaction time changes while performing a concurrent low-force and high-force motor task in young and ...
Ria eWolkorte +2 more
doaj +1 more source