Results 71 to 80 of about 17,265,580 (249)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Reaction time on fencing and karate high level athletes [PDF]

open access: yes, 2008
The great speed of the actions in combat sports makes very difficult to react quickJy without mistakes. If the fighter had longer time to react, their reaction would be more accurate.
Sillero Quintana, Manuel   +3 more
core  

Neurocognitive abilities in soccer athletes are different from healthy non-athletes subjects

open access: yesIraq Medical Journal, 2017
Objectives This study was conducted to compare the reaction time & anticipation skills of football players with non-athletes. Methods Participants of the study were 10 male soccer players and 10 male non-athletes.
A Shadmehr, H Padash, S A Arsalan
doaj  

Reactive agility training selectively improves choice reaction and footwork-stroke performance in young male table tennis players: a randomized controlled trial

open access: yesFrontiers in Physiology
IntroductionThis randomized controlled trial compared the task-specific effects of 6 weeks of QuickBoard-assisted reactive agility training (RAT) and pre-planned agility training (PPAT) in young male table tennis players.MethodsForty young male Chinese ...
Mingquan Zhang   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Decision making under time pressure: an independent test of sequential sampling models [PDF]

open access: yes, 1999
Choice probability and choice response time data from a risk-taking decision-making task were compared with predictions made by a sequential sampling model. The behavioral data, consistent with the model, showed that participants were less likely to take
Busemeyer, Jerome R.   +2 more
core   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Truth and consequence: a look behind the Vatican's ban on contraception

open access: yes, 2008
With these words slamming the door on Catholics’use of modern contraceptives, Pope Paul VI cleaved the Catholic church into irreconcilable factions 40 years ago. The majority, unable to reconcile the rigid encyclical with their need for an updated sexual
Catholics for Choice
core  

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