Results 81 to 90 of about 1,712,907 (361)

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

The Effects of a Marathon Effort on Psychomotor Performance and Catecholamine Concentration in Runners over 50 Years of Age

open access: yesApplied Sciences, 2020
Long-distance running and, in particular, running marathons has become an increasingly popular activity among the elderly. The aim of the study was to examine the effects of a marathon effort on the psychomotor performance and catecholamine concentration
Jan Chmura   +9 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Effect of a plant-based nootropic supplement on reaction time, choice reaction time, and anticipation in healthy adults.

open access: yes, 2023
This project will examine the impact of taking a nootropic on simple reaction time, choice reaction time and anticipation in healthy adults.
Dr Andrea Utley
core   +1 more source

Modeling choice and reaction time during arbitrary visuomotor learning through the coordination of adaptive working memory and reinforcement learning

open access: yesFrontiers in Behavioral Neuroscience, 2015
Current learning theory provides a comprehensive description of how humans and other animals learn, and places behavioral flexibility and automaticity at heart of adaptive behaviors.
Guillaume Viejo   +3 more
semanticscholar   +1 more source

Simultaneous modeling of choice, confidence, and response time in visual perception.

open access: yesPsychology Review, 2023
How can choice, confidence, and response times be modeled simultaneously? Here, we propose the new dynamical weighted evidence and visibility (dynWEV) model, an extension of the drift-diffusion model of decision-making, to account for choices, reaction ...
Sebastian Hellmann   +2 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

EEG correlates of cognitive load in a multiple choice reaction task.

open access: yesActa Neurobiologiae Experimentalis, 2020
The present study aimed to examine EEG correlates of cognitive load in a task, in which multiple stimulus‑response mappings have to be maintained in working memory (WM) combined with selective inhibition of irrelevant stimulus‑response mappings on every ...
S. A. Schapkin   +3 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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