Results 241 to 250 of about 76,116 (300)

UGT1A1 genotype testing for irinotecan: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 2986-3001, September 2026.
Abstract Irinotecan, a topoisomerase I inhibitor, is available as both non‐pegylated and pegylated formulations. The non‐pegylated formulation is licensed for use in advanced colorectal cancer either in combination with other agents or as monotherapy.
Dharmisha Chauhan, Cinzia Dello Russo, Jack Thompson, Dyfrig A. Hughes, Katherine Payne, Maria Tsakiroglou, Paul Ross, Rena Chauhan, Simon Jenkinson, Jessica Keen, Sophie Harding, Eleanor Lau, Michael Braun, Roshan Agarwal, Richard Adams, Elisabeth Rolf, Farah Al‐Sheikhli, Sarah Mitchell, Ruth Hammond, Rosie Roberts, Lorna Cairns, Shirley Heggarty, Janet Graham, Justin Mencel, Munir Pirmohamed   +24 more
wiley   +1 more source

Extended left hepatectomy with sequential triple-vessel resection and reconstruction for advanced cholangiocarcinoma: a case report. [PDF]

J Surg Case Rep
Younan EZ, Jiwane M, Bains HK, Crawford MD, Sandroussi C, Laurence JM.   +5 more
europepmc   +1 more source

Efficacy and Safety of First‐Line Chemotherapy With Gemcitabine Plus Nab‐Paclitaxel in Unresectable Gallbladder Cancer

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Purpose The purpose of this study is to evaluate the efficacy and safety of nab‐paclitaxel combined with gemcitabine (AG regimen) as a first‐line chemotherapy for patients with unresectable gallbladder cancer (GBC). Materials and Methods A retrospective analysis was conducted on patients diagnosed with GBC via histological examination ...
Yue Yang, Ziyou Wu, Yidi Zhu, Yu Zhang, Zhe Zhou, Xiaoling Song, Ziyi Yang, Shilei Liu, Runfa Bao, Xuefeng Wang, Xiangsong Wu, Wei Gong   +11 more
wiley   +1 more source

Modern therapeutic approaches in cholangiocarcinoma: A narrative review of key biomarkers and clinical trials. [PDF]

Transl Oncol
Almeida A, Manzi J, Hoff C, Kadri H, Livingstone A, Gleisner A, Toegel EB, Schulick R, Hoff PM, Vianna R, Abreu P.   +10 more
europepmc   +1 more source

Development of a Prognostic Survival Risk Score for Lung Cancer Patients With Type 2 Diabetes Mellitus: A Territory‐Wide Retrospective Cohort Study

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Background Lung cancer is a leading cause of cancer‐related mortality, and its prognosis is often affected by comorbidities such as type 2 diabetes mellitus (T2DM). This study aimed to identify survival risk factors for lung cancer patients with T2DM, evaluate the predictive models, and develop a risk score system for survival prediction ...
Claire Chenwen Zhong, Junjie Huang, Zhaojun Li, Yu Jiang, Zehuan Yang, Jinqiu Yuan, Xiaodan Huang, Xiaofang Liu, Han Wang, Jonathan Poon, Qi Dou, Arthur Sung, Martin C. S. Wong   +12 more
wiley   +1 more source

Metachronous cholangiocarcinoma following pancreaticoduodenectomy and the potential role of a migrated pancreaticojejunal stent: a case report and review of the literature. [PDF]

Front Oncol
Chen J, Wang FY, Huang YX, Zhu LY.
europepmc   +1 more source

Single‐Cell Transcriptome of Anaplastic Thyroid Cancer Reveals Immunosuppressive Tumor Microenvironment Remodeling

Cancer Medicine, Volume 15, Issue 9, September 2026.
Single‐cell RNA sequencing of anaplastic thyroid cancer (ATC) and aggressive papillary thyroid cancer (PTC) revealed coordinated tumor‐intrinsic and immune reprogramming during thyroid cancer dedifferentiation. ATC exhibited MAPK/PI3K co‐activation, p53 suppression, E2F activation, cytotoxic lymphocyte exhaustion, enhanced regulatory T‐cell ...
Saeko Tahara, Akiko Iguchi‐Manaka, Naoto Takeuchi, Tomohei Matsuo, Akira Shibuya, Kazuko Shibuya, Haruka Ozaki   +6 more
wiley   +1 more source

Salvage resection for FGFR2 fusion-positive intrahepatic cholangiocarcinoma after pemigatinib therapy: a case report and literature review. [PDF]

Front Oncol
Kang Y, Xie F, Wu Z, Zhou Y, Wen T, Zhang X.   +5 more
europepmc   +1 more source

Expression of Concern: Targeting tumor-associated genes, immune response, and circulating tumor cells in intrahepatic cholangiocarcinoma: Therapeutic potential of Atractylodes lancea (Thunb:) DC. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Multifunctional LA and PTMC coating for biliary stents to combat cholangiocarcinoma proliferation in obstruction. [PDF]

iScience
Jin L, Wang Y, Liu Y, Mao Q, Feng B, Xin J, Zhang Y, Li L, Guan X, Wu X, Wang Z, Yu L, Zhang L, Zan R.   +13 more
europepmc   +1 more source