Results 221 to 230 of about 96,828 (293)

Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications

MedComm, Volume 7, Issue 5, May 2026.
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang, Xiaoqing Wang, Kai Luo, Tikam Chand Dakal, He Bai, Caiming Xu, Guixin Zhang   +6 more
wiley   +1 more source

Efficacy and safety of immune checkpoint inhibitors in patients with high microsatellite instability/mismatch repair-deficient advanced cholangiocarcinoma: A propensity score-matched study. [PDF]

JHEP Rep
Piao M, Yang X, Li C, Zhao J, Zhang N, Li J, Huang Z, Li S, Sun B, Yang X, Zhao H.   +10 more
europepmc   +1 more source

Investigation of Potential Risks in Bio‐Based Food Contact Materials (FCMs) From Microbial Exploitation of Agricultural Wastes: Case Studies of Bacterial Cellulose and Nisin

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT In the context of the circular economy and the increasing demand for safe and sustainable packaging, this work addresses the safety assessment of food contact materials (FCMs) derived from agro‐industrial by‐products. Despite growing interest in these bio‐based materials, the literature still lacks a structured safety‐assessment framework able
Marianna Ciccone, Emmanouil Tsochatzis, Joel Armando Njieukam, Lorenzo Siroli, Davide Gottardi, Rosalba Lanciotti, Francesca Patrignani   +6 more
wiley   +1 more source

Mixed Reality‐Assisted Thoracic Endovascular Aortic Repair: A Retrospective Study on Efficacy and Safety

Annals of Noninvasive Electrocardiology, Volume 31, Issue 3, May 2026.
This study demonstrates the significant clinical utility of Mixed Reality (MR) in Thoracic Endovascular Aortic Repair (TEVAR). Our findings reveal that MR‐assisted workflows enhance patient comprehension and satisfaction preoperatively and provide intuitive intraoperative navigation.
Jian‐Jun Gu, Teng‐Yue Zhao, Xiao‐Chao Tian, Ying‐Chao Ma   +3 more
wiley   +1 more source

LncRNA PVT1 promotes proliferation, migration and invasion of cholangiocarcinoma by regulating the expression of SOCS2. [PDF]

Sci Rep
Cao X, Zhang L, Chen K, Fu H, Yi H, Bai Z, Zhao L, Yu A.   +7 more
europepmc   +1 more source

Cholangiolocellular Component Predicts a Biologically Distinct Subgroup of Mass‐Forming Intrahepatic Cholangiocarcinoma

Cancer Science, Volume 117, Issue 5, Page 1510-1523, May 2026.
We identified two distinct molecular subgroups of mass‐forming intrahepatic cholangiocarcinoma (MF‐iCCA) based on the presence of a histological cholangiolocellular carcinoma (CLC) component. The CLC‐related molecular subgroup showed better prognosis and highly angiogenic features, as confirmed by both genetic analysis and morphological observation ...
Naoto Kubota, Ken Yamazaki, Yasuhito Arai, Minoru Esaki, Nobuyoshi Hiraoka, Hirofumi Shirakawa, Moriaki Tomikawa, Tatsuhiro Shibata, Michiie Sakamoto, Hidenori Ojima   +9 more
wiley   +1 more source

Survival and Recurrence in Liver Transplant Patients With Intrahepatic Cholangiocarcinoma and Hepatocellular Carcinoma. [PDF]

Ann Transplant
Jeong IJ, Hwang S, Ahn CS, Moon DB, Ha TY, Song GW, Jung DH, Park GC, Kang WH, Yoon YI, Lee SG.   +10 more
europepmc   +1 more source

Issue Information

Liver International Communications, Volume 7, Issue 2, June 2026.
wiley   +1 more source

Diagnostic and Prognostic Values of Bile Biomarkers for Malignant Biliary Stenosis

Liver International, Volume 46, Issue 5, May 2026.
ABSTRACT Introduction Differentiating between malignant and benign biliary strictures remains a clinical challenge because current diagnostic tools have limited sensitivity. The detection of tumour‐related biomarkers directly in bile, which is in close contact with the lesion, may enhance diagnostic accuracy.
E. Gigante, V. Untereiner, S. Caruso, R. Rhaiem, L. Grados, C. Boulagnon‐Rombi, S. Adam, G. D. Sockalingum, R. Garnotel, G. Thiefin   +9 more
wiley   +1 more source

Genomic and transcriptomic insights into aflatoxin-induced intrahepatic cholangiocarcinoma: an integrated pathway and meta-analysis study. [PDF]

Front Genet
Li F, Ma Y, Cheng Y, Zou S.
europepmc   +1 more source