Results 221 to 230 of about 76,116 (300)

Clinical Outcomes of Multi‐Hole Covered Self‐Expandable Metal Stents for Malignant Distal Biliary Obstruction: A Retrospective Comparative Study With an Exploratory Evaluation of 6‐mm Devices

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Covered self‐expandable metal stents (CSEMS) are widely used for malignant distal biliary obstruction (MDBO), but cholecystitis, post‐endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP), stent migration, and recurrent biliary obstruction (RBO) remain clinically important limitations.
Akinobu Koiwai   +5 more
wiley   +1 more source

Efficacy and Safety of Endoscopic Ultrasound‐Guided Biliary Drainage in the Management of Malignant Hilar Biliary Obstruction: A Multicenter Retrospective Cohort Study

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Malignant hilar biliary obstruction (MHBO) remains challenging for biliary decompression. Although endoscopic ultrasound‐guided biliary drainage (EUS‐BD) has emerged as an alternative to endoscopic retrograde cholangiopancreatography‐guided BD (ERCP‐BD), evidence regarding EUS‐BD for MHBO is limited. Aims To evaluate the efficacy and safety of
Takuji Iwashita   +12 more
wiley   +1 more source

Efficacy and safety of durvalumab plus gemcitabine-cisplatin in combined hepatocellular-cholangiocarcinoma versus cholangiocarcinoma. [PDF]

open access: yesESMO Open
Hsu CC   +21 more
europepmc   +1 more source

HierAnom‐Path: Zero‐Shot Rare Cancer Detection in Histopathology via Hierarchical Foundation Model Adaptation

open access: yesComputational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Rare cancers collectively represent 20%–25% of all malignancies yet yield fewer than 50 annotated whole‐slide images (WSIs) per subtype in publicly available archives, rendering supervised deep learning inapplicable. We present HierAnom‐Path, to the best of our knowledge, the first framework for zero‐shot rare cancer anomaly detection in ...
Noora Saleem Jumaah   +5 more
wiley   +1 more source

Molecular Tumor Boards in Malignant Melanoma: Uncovering Challenges and Opportunities in a Bicenter Retrospective Analysis in Germany

open access: yesInternational Journal of Cancer, Volume 159, Issue 9, Page 2290-2299, 1 November 2026.
Molecular tumor boards (MTB), interdisciplinary teams that use tumor genomic data to guide personalized treatment decisions, have emerged as a promising strategy in melanoma care, although their real‐world clinical impact remains uncertain. This retrospective study evaluated advanced melanoma patients to assess molecularly guided treatment ...
Glenn Geidel   +26 more
wiley   +1 more source

A Serum lncRNA Signature Determines Oncogenic YAP Activity in Cancer Patients

open access: yesInternational Journal of Cancer, Volume 159, Issue 7, Page 1829-1843, 1 October 2026.
Long non‐coding RNAs (lncRNAs) signatures are promising cancer biomarkers, since their dysregulation in tumors is reflected in body fluids. In this study, next‐generation sequencing, bioinformatics, and gene expression data were combined to investigate an lncRNA signature linked specifically to the cancer‐promoting YAP in several cancer types ...
Fabian Rose   +24 more
wiley   +1 more source

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