Results 201 to 210 of about 96,828 (293)

Nuclear Mechanotransduction Across the Metastatic Cascade: Decoding Spatiotemporal Heterogeneity in Cancer Dissemination

Advanced Science, Volume 13, Issue 25, 4 May 2026.
Tumor metastasis results from complex interactions between cancer cells and mechanical microenvironments. We propose a “nucleus‐centered, cross‐stage mechanical signal decoding” model, highlighting how nuclear mechanosensors interpret forces at different stages.
Linqi Song, Jingyang Liu, Xue Wang, Minpu Zhang, Changgang Sun   +4 more
wiley   +1 more source

External Beam Radiation Therapy for Intrahepatic Cholangiocarcinoma. [PDF]

J Gastrointest Cancer
Hotca AE, Feng M.
europepmc   +1 more source

An XGBoost‐Based Multicenter Model for Predicting HBV‐Related Hepatocellular Carcinoma: Development and Validation

Cancer Medicine, Volume 15, Issue 5, May 2026.
We developed a web‐based interactive tool to estimate individualized HCC risk in chronic HBV patients, enabling clinicians to input real‐time data for personalized risk probabilities and evidence‐based actionable recommendations. ABSTRACT Background The 5‐year survival rate for hepatocellular carcinoma (HCC) is stage‐dependent, yet existing models lack
Yong Lin, Hai‐Yan Zhuo, Hui‐Wen Song, Li‐Na Zhou, Mei‐Zhu Hong, Chun Lin, Peng‐Fei Guo, Jin‐Shui Pan   +7 more
wiley   +1 more source

Lipidomic analysis of bile from patients with extrahepatic cholangiocarcinoma. [PDF]

PLoS One
Choi SJ, Kim HJ, Kwon SW, Kim WS, Kim JS.   +4 more
europepmc   +1 more source

The Clinical Benefits of Nutritional Supplementation Across the Chemotherapy Journey in Cancer Patients: A Multicenter Prospective Cohort Study

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Purpose This study aimed to explore the clinical benefits of receiving nutritional supplementation (NS) throughout the whole course of chemotherapy. Methods This multicenter prospective cohort study totally included 251 cancer patients requiring nutritional support and scheduled for chemotherapy.
Jia‐Xin Huang, Si‐Wei Xie, Hui‐Min Qu, Zhi‐Gang Feng, Xin‐Yi Wang, Jun Zhao, Quan‐Fu Li, Ying Jiang, Feng Chen, Jun Li, Shun‐Chun Yao, Ming‐Hui Zhang, Xian Shen, Xiao‐Dong Chen, Ning Li, Xi Zhang, Le Tian, Min Yang, Meng Tang, Chen‐Xin Song, Bao‐Hua Zou, Sheng‐Ling Qin, Rong Qin, Ming‐Hua Cong   +23 more
wiley   +1 more source

Combined hepatocellular-cholangiocarcinoma: a contemporary pathologic and molecular perspective. [PDF]

J Liver Cancer
Chung T.
europepmc   +1 more source

A Phase 1, Open‐Label, Single‐Dose Study of the Effect of Hepatic Impairment on the Pharmacokinetics of Erdafitinib, an FGFR Inhibitor

Clinical Pharmacology in Drug Development, Volume 15, Issue 5, May 2026.
Abstract Erdafitinib, an oral pan‐FGFR inhibitor is extensively metabolized in the liver. This open‐label, single‐dose, phase 1 study evaluated the pharmacokinetics (PK) of erdafitinib in participants with hepatic impairment versus healthy controls. Overall, 26 participants were enrolled.
Wei Zhu, Peter Hellemans, Anna Mitselos, Marc De Meulder, Juhui James Jiao, Hui Tian   +5 more
wiley   +1 more source

Radiological Loco-Regional Treatments for Cholangiocarcinoma: A Systematic Review of the Literature. [PDF]

Liver Int
Pallas D, Campani C, Sutter O, Nahon P, Ganne-Carrié N, Seror O, Nault JC.   +6 more
europepmc   +1 more source

Oncogenic driver and therapeutic target: Prolactin signalling axis in retroperitoneal sarcoma

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
Retroperitoneal sarcoma cells can secrete prolactin into the bloodstream, inducing hyperprolactinaemia, which subsequently triggers metabolic reprogramming, such as glucose metabolism. SOX4 can function as a transcription factor that facilitates PRL transcription.
Fu'an Xie, Lingwei Gu, Kunrong Yang, Shuai Wang, Mengmeng Xiao, Guangting Yan, Quan Zhang, Rubing Liang, Aobo Zhuang, Zhe Xi, Yujia Niu, Yanhua Chen, Xiaogang Xia, Linlin Qu, Bin Zhao, Weibing Li, Ting Wu, Chundong Yu, Chenghua Luo, Houzhao Wang, Lanlan Lian, Wengang Li   +21 more
wiley   +1 more source