Results 181 to 190 of about 79,213 (303)

Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy

open access: yesImmunology &Cell Biology, EarlyView.
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley   +1 more source

Phase I/II Prospective Study on Endoscopic Ultrasound‐Guided Hepaticogastrostomy as Primary Drainage for Unresectable Malignant Hilar Biliary Obstruction

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Various drainage methods have been used for unresectable malignant hilar biliary obstruction (MHBO). However, controlling cholangitis and obstructive jaundice is still challenging. We performed a phase I/II study of endoscopic ultrasound‐guided hepaticogastrostomy (EUS‐HGS) as primary drainage for MHBO.
Tomoki Ogata   +7 more
wiley   +1 more source

MCL-1 as a tumor microenvironment-linked survival node in cholangiocarcinoma. [PDF]

open access: yesFront Oncol
Hashida H   +4 more
europepmc   +1 more source

Mechanism of Fibrotic Anastomosis Formation in Endoscopic Ultrasound‐guided Hepaticogastrostomy Using a Plastic Stent: Insights From an Autopsy Case of Perihilar Cholangiocarcinoma

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Endoscopic ultrasound‐guided hepaticogastrostomy (EUS‐HGS) is an established alternative to other biliary drainage techniques for treating malignant biliary obstruction. Although the anastomosis created by EUS‐HGS is believed to mature within several weeks, histopathological evidence supporting this assumption remains limited, particularly in ...
Kosuke Maehara   +9 more
wiley   +1 more source

Optimal Stenting Strategy During Chemotherapy: Impact of Time to First Reintervention on Survival in Malignant Hilar Biliary Obstruction

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Advances in chemotherapy have increased survival in biliary tract cancer patients, and reports of the effectiveness of neoadjuvant therapy are emerging. Accordingly, developing optimal drainage strategies under chemotherapy is important.
Katsuhiko Sato   +8 more
wiley   +1 more source

Clinical Utility and Safety of a Novel Ultraslim Catheter‐Type Peroral Cholangioscope/Pancreatoscope: A Single‐Center Case Series

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Peroral cholangioscopy (POCS) and peroral pancreatoscopy (POPS) enable direct intraductal visualization for pancreatobiliary disease diagnosis and management. Nonetheless, conventional devices have relatively large diameters, limiting their use in narrow ducts.
Hiroyuki Kojima   +13 more
wiley   +1 more source

Erratum: CSNK2A1-mediated MAX phosphorylation upregulates HMGB1 and IL-6 expression in cholangiocarcinoma progression. [PDF]

open access: yesHepatol Commun
Yang B   +12 more
europepmc   +1 more source

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