Results 181 to 190 of about 71,405 (265)
A Modular and Programmable Cas13d Platform for RNA Single Nucleotide Variant Detection
Advanced Science, Volume 13, Issue 32, 9 June 2026.A scenario‐guided Cas13d platform enables configurable single nucleotide variant ribonucleic acid diagnostics through rule‐based guide design and ribonucleic acid binding domain engineering, supporting amplification‐free ultrasensitive detection and amplification‐coupled robust detection for accurate mutation classification in clinical tumor specimens.
Zeyu Wang +8 more
wiley +1 more source
Distal cholangiocarcinoma with rare progression to distal femoral metastasis: a case report and literature review. [PDF]
Front Med (Lausanne)Du N, Gao Y, Sun H, Zhang X.
europepmc +1 more source
Advanced Science, Volume 13, Issue 34, 19 June 2026.ABSTRACT Blood‐based liquid biopsies hold transformative potential for non‐invasive cancer management, but current approaches relying on rare circulating tumor components limit their broad clinical utility. Platelets, abundant in blood and mediating diverse cancer‐associated responses, represent a compelling yet largely unexplored alternative.
Yan Ma +28 more
wiley +1 more source
A deceptively benign biliary lesion revealing an ALK‐rearranged intrahepatic cholangiocarcinoma
Histopathology, Volume 89, Issue 1, Page 189-192, July 2026.
Anne‐Cécile Brunac +5 more
wiley +1 more source
Biotechnology and Applied Biochemistry, Volume 73, Issue 3, Page 1626-1646, June 2026.ABSTRACT Gastrointestinal cancers (GICs) constitute one of the leading causes of cancer‐related morbidity and mortality worldwide. Despite currently available therapeutic strategies, new approaches and procedures are needed for their prevention and treatment.
Raúl Vergara +5 more
wiley +1 more source
Biobanked Liver Organoids: A Roadmap for Precision Hepatology
BioEssays, Volume 48, Issue 6, June 2026.Cryopreservation‐enabled biobanking transforms archived human liver tissue into standardized, quality‐controlled organoid resources. By decoupling organoid generation from the availability of fresh tissue, this infrastructure enables scalable, reproducible, and clinically actionable liver models that support precision hepatology, drug development, and ...
Elisa J. Cabré +5 more
wiley +1 more source
Comprehensive Genomic Profiles of Patients With Biliary Tract Cancer
Cancer Medicine, Volume 15, Issue 6, June 2026.ABSTRACT Purpose Biliary tract cancer (BTC) represents a heterogeneous disease with highly lethal malignancy and poor clinical outcomes. Here, we aimed to evaluate its genomic profiles to promote the development of precision medicine for BTC. Materials and Methods Genomic analysis of 134 BTC patients was performed by using targeted panel sequencing in ...
Xia Yang +4 more
wiley +1 more source
Cancer Medicine, Volume 15, Issue 6, June 2026.ABSTRACT Aim Upper gastrointestinal bleeding (UGIB) is associated with an unfavorable outcome in cancer patients. In patients with biliary tract cancer (BTC), data on the incidence, management, and prognostic implications of UGIB are limited. This study investigated the prevalence, treatment efficacy, and prognostic factors associated with UGIB in BTC.
Jan Christoph Schumacher +8 more
wiley +1 more source
Benign Migratory Glossitis in a Patient With Cholangiocarcinoma due to Targeted Drug Therapy
Clinical Case Reports, Volume 14, Issue 6, June 2026.Oral Manifestation of Targeted Therapy: Benign Migratory Glossitis. ABSTRACT During the course of targeted drug therapy, a cancer patient may manifest a myriad of systemic and oral toxicities. This has a direct impact on the patient's QOL. This clinical image highlights a rarely‐encountered oral mucosal alteration called benign migratory glossitis in a
Sandeep Gurav +2 more
wiley +1 more source