Results 171 to 180 of about 71,405 (265)

The Role of Long Noncoding RNAs in Modulation of Stress Granules in Cancer

Journal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Stress granules are dynamic cellular structures that arise in response to stress. They play an important role in cancer cell survival by modulating multiple stress responses. Long noncoding RNAs (lncRNAs) have been identified as crucial regulators of stress granule (SG) dynamics, influencing cancer development and treatment resistance. LncRNAs
Nazlı Şevval Menemenli, Bünyamin Akgül   +1 more
wiley   +1 more source

HERACLIS_BLV_D: Adherence to Real‐Life Therapy With Bulevirtide in Chronic Hepatitis D

Journal of Viral Hepatitis, Volume 33, Issue 7, July 2026.
ABSTRACT Daily subcutaneous bulevirtide (BLV) 2 mg has been approved as first‐line treatment for chronic hepatitis D (CHD), but long‐term real‐world adherence data are limited. We assessed adherence rates during BLV therapy and their impact on treatment response. HERACLIS_BLV_D study (NCT05928000) included adult CHD patients initiating BLV 2 mg/day and
Dimitra Lakiotaki, Margarita Papatheodoridi, Vasilios Sevastianos, Kalliopi Zachou, Dimitrios Christodoulou, John Koskinas, Melanie Deutsch, Alexandra Alexopoulou, Ioannis Elefsiniotis, Christos Triantos, Elena Gigi, Theodoros Androutsakos, Dimitrios S. Karagiannakis, Iliana Mani, Dimitrios Dimitroulopoulos, Maria Mela, Emmanouil Sinakos, Spyros Michopoulos, Konstantinos Mimidis, Nikolaos Papadopoulos, Athanasios Kontos, Christos Veretanos, Dimitrios Lymperopoulos, George Giannoulis, Vasilios Papadimitropoulos, Evdoxia Avramopoulou, Alkistis Papatheodoridi, Spyridon Pantzios, Larisa Vasilieva, Hariklia Kranidioti, Emmanouil Koullias, Athanasios Soukovelos, Paraskevi Fytili, John Vlachogiannakos, Evangelos Cholongitas, Spilios Manolakopoulos, Ioannis Goulis, George Dalekos, George Papatheodoridis   +38 more
wiley   +1 more source

Outcomes of Liver Transplant Versus Partial Hepatectomy for Perihilar Cholangiocarcinoma Patients Requiring Arterial Reconstruction

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Background and Aims Liver resection (LR) and orthotopic liver transplantation (OLT) are therapeutic options for locally advanced perihilar cholangiocarcinoma (pCCA) requiring hepatic artery reconstruction (HAR). This study aimed to compare short‐ and long‐term outcomes of LR and OLT. Outcomes were major vascular complications, 90‐day mortality,
Edoardo Poletto, Pim B. Olthof, Andrea Ruzzenente, Jean‐Philippe Adam, Ian P. J. Alwayn, Emmanuel Boleslawski, Marieke T. de Boer, Alexandre Chebaro, Laurence Chiche, Cristina Dopazo, Jeroen Dubbeld, Joris I. Erdmann, Abdul Hakeem, Minneke J. Coenraad, Hendrien Kuipers, Jean‐Yves Mabrut, Charlotte Maulat, Shishir K. Maithel, Vincent E. de Meijer, Kayvan Mohkam, Sarwa Darwish Murad, Fabrice Muscari, Jens Rolinger, Wojciech G. Polak, Michel Rayar, Francesca Ratti, Fabien Robin, Andreas A. Schnitzbauer, Ernesto Sparrelid, Frederike G. I. Van Vilsteren, Robert J. Porte, Frederik J. H. Hoogwater, Bas Groot Koerkamp, on behalf of the Perihilar Cholangiocarcinoma Collaboration Group, L. Aldrighetti, W. O. Bechstein, M. A. de Boer, S. Büttner, I. Capobianco, R. Charco, L. C. Franken, S. Gilg, C. Gomez‐Gavara, A. Guglielmi, T. M. van Gulik, J. Heil, H. Jansson, G. Kazemier, P. Lodge, R. Marino, S. Nadalin, T. A. Nguyen, R. Prasad   +52 more
wiley   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, Volume 13, Issue 35, 24 June 2026.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Ectopic β-hCG-Expressing Hepatic Neoplasm with Cutaneous Metastasis in a Young Postpartum Woman: A Case Report and Literature Review. [PDF]

Int J Womens Health
Zheng Y, Yang M, Xu W, Huang P.
europepmc   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, Volume 13, Issue 35, 24 June 2026.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Calciphylaxis as a Rare Complication Associated with Pemigatinib Treatment-A Case Report. [PDF]

Curr Oncol
Čular K, Hamzić DT, Smiljanić Tomičević L, Buzina DŠ, Bradamante M, Simetić L, Bilić I, Belev B.   +7 more
europepmc   +1 more source

Targeting m6A Reader YTHDF1 Enhances Antitumor Immunity and Potentiates Anti‐PD‐L1 Efficacy in Intrahepatic Cholangiocarcinoma

Advanced Science, Volume 13, Issue 32, 9 June 2026.
The m6A reader YTHDF1 drives intrahepatic cholangiocarcinoma (ICC) progression by remodeling the tumor immune microenvironment. YTHDF1 promotes MDSC recruitment via activation of m6A‐FOSL2‐CXCL6/CXCR2 axis, thereby suppressing CD8+ T cell infiltration and function.
Li Luo, Ziqin Liu, Zimin Song, Dong Zhang, Cong Liang, Fei Fang, Kai Lei, Lina Wang, Weikang Chen, Shunli Shen, Ming Kuang, Xiaoxing Li, Jun Yu, Shiyan Wang, Lixia Xu   +14 more
wiley   +1 more source

Endobiliary Photodynamic Therapy in Cholangiocarcinoma: Clinical Outcomes, Patient Selection, and Procedural Context. [PDF]

Curr Oncol
Zhang X, Jiang A.
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, Volume 13, Issue 35, 24 June 2026.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source