Results 151 to 160 of about 76,116 (300)
The Journal of Pathology, EarlyView.Abstract Ductular reactions (DRs) are dynamic and complex multicellular responses that occur as a result of various hepatic injuries. Precise identification and quantification of the extent of DRs is a cornerstone of pre‐clinical modelling of liver disease, with links to inflammation, fibrosis, regeneration, and disease severity.
Nathalie Feeley +15 more
wiley +1 more source
Effects of proton therapy on the tumor immune system and clinical implications: A review
Precision Radiation Oncology, EarlyView.Proton therapy is a novel radiotherapy technique. We review four aspects of proton therapy: application in various tumors, effects on the tumor immune system, combination with other therapies, and future challenges. By presenting these aspects in this review, we aim to inspire clinical interventions.
Rundong Liu +5 more
wiley +1 more source
VIEW, EarlyView.Pancreatic ductal adenocarcinoma exhibits marked angiogenic and immune heterogeneity. We identified 28 angiogenesis‐associated immune genes and developed a seven‐gene AIGScore model comprising FGF2, ADGRB3, MMP2, TYMP, VASH1, VEGFD, and ITGAV. A high AIGScore was associated with poor survival, an immunosuppressive tumor microenvironment, and reduced ...
Qing Chang +4 more
wiley +1 more source
Does Surgical Approach Influence Benchmark Attainment in Intrahepatic Cholangiocarcinoma?
World Journal of Surgery, EarlyView.Intrahepatic cholangiocarcinoma (ICC) is a rare malignancy with rising incidence and poor prognosis. Surgical resection remains the only curative option, with outcomes driven by R0 margins and lymphadenectomy (LND). While open liver resection (OLR) is standard, laparoscopic (LLR) and robotic liver resection (RLR) are increasingly used, with concerns ...
Delphine Gastineau +40 more
wiley +1 more source
World Journal of Surgery, EarlyView.Major liver surgery is associated with significant physiological stress and a high rate of postoperative complications. Prehabilitation aims to enhance physiological reserve before surgery. Despite the growing volume of liver resections worldwide, the impact of prehabilitation on clinical and economic outcomes in patients undergoing elective liver ...
Lyrics M. Noba +6 more
wiley +1 more source
Journal of Medical Imaging and Radiation Oncology, EarlyView.ABSTRACT Introduction Dynamic Single Photon Emission Computed Tomography (dynSPECT) is an advanced functional imaging modality that enables estimation of temporal changes in radiopharmaceutical distribution and physiological function. While dynSPECT has been employed in several clinical applications, it has not been widely applied to liver imaging ...
Bader Aloufi +3 more
wiley +1 more source
Metabolic syndrome and the risk of cholangiocarcinoma: a hospital-based case–control study in China
, 2018 Jianping Xiong,1,* Xin Lu,1,* Weiyu Xu,1,* Yi Bai,1 Hanchun Huang,1 Jin Bian,1 Lei Zhang,1 Junyu Long,1 Yiyao Xu,2 Zhenjie Wang,2 Haitao Zhao1 1Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and ...
Xiong J +10 more
core
Clinical Need and Research Investment for Liver Cancer in Australia
Asia-Pacific Journal of Clinical Oncology, EarlyView.Liver cancer incidence and mortality rates have been rising in comparison to other common cancers, but research funding has not been commensurate. ABSTRACT Aim This study aims to better understand factors driving the rising burden and costs of primary liver cancer (PLC) in Australia, identify key epidemiological trends, and ascertain investment in PLC ...
Romario Nguyen +15 more
wiley +1 more source
Oncology Inpatient Resuscitation Planning and Long‐Term “Rapid Response Call” Outcomes
Asia-Pacific Journal of Clinical Oncology, EarlyView.Optimal end‐of‐life care involves a patient‐centered approach. The dual audits presented in this study show that a proportion of oncology patients receiving palliative‐intent cancer treatment continue to be managed in hospital without a resuscitation plan and may undergo care escalation to a “rapid response” intervention despite poor prognosis ...
Dhanashree Tikhe +3 more
wiley +1 more source
Andrology, EarlyView.ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick +7 more
wiley +1 more source