Results 131 to 140 of about 79,213 (303)

Angiogenesis‐associated immune genes as prognostic markers and predictors of immunotherapy response in pancreatic ductal adenocarcinoma

VIEW, EarlyView.
Pancreatic ductal adenocarcinoma exhibits marked angiogenic and immune heterogeneity. We identified 28 angiogenesis‐associated immune genes and developed a seven‐gene AIGScore model comprising FGF2, ADGRB3, MMP2, TYMP, VASH1, VEGFD, and ITGAV. A high AIGScore was associated with poor survival, an immunosuppressive tumor microenvironment, and reduced ...
Qing Chang, Qian Wang, Xiumei Jiang, Yongmei Yang, Ailin Qu   +4 more
wiley   +1 more source

The morphomolecular features of cholangiocarcinoma in the personalised era [PDF]

Cholangiocarcinoma is a group of diverse invasive malignancies arising along the biliary tract. The outcomes for patients with cholangiocarcinoma remain poor but an understanding of molecular aberrations and subsequent targeted therapies to these have ...
Carpino, Guido, Kendall, Timothy J., Field, Daniel T., Kendall, Timothy J.; id_orcid, Field, Daniel, Doukas, Michail   +5 more
core   +1 more source

Establishment and genomic profiling of cholangiocarcinoma cells with functional characterization

Scientific Reports
Cholangiocarcinoma (CCA) is a highly lethal hepatobiliary malignancy, with prognosis is influenced by anatomical subtypes and etiological factors. This study successfully established three CCA cell lines: KKU-097, KKU-466, and KKU-610, from the primary ...
Rattanaporn Jaidee, Apinya Jusakul, Piman Pocasap, Veerapol Kukongviriyapan, Laddawan Senggunprai, Auemduan Prawan, Watcharin Loilome, Attapol Titapun, Apiwat Jareanrat, Vasin Thanasukarn, Natcha Khuntikeo, Nisana Namwat, Yaovalux Chamgramol, Malinee Thanee, Phongsathorn Wichian, Jing Han Hong, Peiyong Guan, Hong Lee Heng, Chawalit Pairojkul, Bin Tean Teh, Sarinya Kongpetch   +20 more
doaj   +1 more source

Cholangiocarcinoma [PDF]

Visceral Medicine, 2016
Alfred, Königsrainer, Nisar P, Malek
openaire   +2 more sources

Improving tumor marker comparability: A case series on harmonizing carbohydrate antigen 19‐9 and carbohydrate antigen 15‐3 measurements across diverse measurement systems

VIEW, EarlyView.
CA19‐9 and CA15‐3 measurements from seven contemporary immunoassay systems were compared using 464 and 499 native serum samples, respectively. Inter‐system correlations were higher for CA15‐3 than for CA19‐9, and only a limited number of systems met biological variation‐derived bias criteria.
Jia Li, Xiaoying Lou, Zongdan Wang, Mengdi Wu, Jing Zhang, Huishuang Gao, Meng Li, Bing Wu, Dongmei Ma, Kuo Zhang, Wei Cui   +10 more
wiley   +1 more source

Obesity and cholangiocarcinoma

World Journal of Gastroenterology, 2013
It is estimated that about half of the population in developed countries are either overweight or obese. In some developing nations obesity rates have increased to surpass those seen in Western countries. This rate increase in obesity has many implications as obesity has been associated with numerous negative health effects including increased risks of
openaire   +2 more sources

YTHDF2 in hepatocellular carcinoma: Bridging m6A modification and cancer progression

VIEW, EarlyView.
Abstract YTH N6‐methyladenosine RNAbinding protein F2 (YTHDF2) is an N6‐methyladenosine (m6A) reader protein that mainly regulates the stability of methylated transcripts through mRNA decay. In the liver, YTHDF2 is involved in metabolic homeostasis, oxidative stress responses, and immune regulation.
Sijie Zang, Dongxue Ge, Wanqi Yang, Haobin Shen, Weihong Ge, Li Li, Dayu Chen, Jinglin Wang   +7 more
wiley   +1 more source

Ureteropelvic junction obstruction caused by metastatic cholangiocarcinoma

, 2019
We describe the rare case of a 61-year-old female with right ureteropelvic junction (UPJ) obstruction caused by metastatic cholangiocarcinoma. Her past medical history was notable for cholangiocarcinoma treated with neoadjuvant chemoradiation and two ...
Robert S. Figenshau (8182992), Nicholas A. Pickersgill (8182986), Alec J. Wright (8182989)   +2 more
core   +1 more source

Perioperative Outcomes of Patients With Pancreatic Neuroendocrine Neoplasms in the Context of Different Body Composition Phenotypes

World Journal of Surgery, EarlyView.
Pancreatic neuroendocrine neoplasms (pNEN) are rare and heterogeneous tumors with increasing incidence. While surgical resection remains the only curative treatment, perioperative outcomes are influenced by patient‐related risk factors. Recent research highlights body composition (BC) as a prognostic marker in oncological and transplantation surgery ...
Fabiola A. Bechtiger, Mariah Herbrich, Hazem K. A. A. Hassan, Jörg Kaiser, Thomas Hank, Magdalena Lewosinska, Deniz Uluk, Osman Öcal, Nicole D. Hildebrand, Steven WM Olde Damink, Franck Billmann, Zoltan Czigany, Mohammed Al‐Saeedi   +12 more
wiley   +1 more source

Leptin enhances cholangiocarcinoma cell growth

, 2008
Cholangiocarcinoma is a strongly aggressive malignancy with a very poor prognosis. Effective therapeutic strategies are lacking because molecular mechanisms regulating cholangiocarcinoma cell growth are unknown.
De Morrow S., Glaser S., C. Rychlicki, G. Svegliati Baroni, G. Fava, Marucci L., A. Di Sario, Francis H., Alvaro D., Alpini G., BENEDETTI, Antonio, A. Benedetti, L. Trozzi, SVEGLIATI BARONI, Gianluca, D. Alvaro, S. Glaser, FAVA, GABRIELE, C. Candelaresi, I. Bearzi, Bearzi I., G. Svegliati-Baroni, S. Demorrow, M. Marzioni, MARZIONI, MARCO, S. Saccomanno, ALVARO, Domenico, G. Alpini, Di Sario A., TROZZI, Luciano, Venter J., L. Marucci, J. Venter, Rychlicki C., SACCOMANNO, STEFANIA, Candelaresi C., H. Francis   +35 more
core   +1 more source