Results 131 to 140 of about 76,116 (300)

Establishment and genomic profiling of cholangiocarcinoma cells with functional characterization

Scientific Reports
Cholangiocarcinoma (CCA) is a highly lethal hepatobiliary malignancy, with prognosis is influenced by anatomical subtypes and etiological factors. This study successfully established three CCA cell lines: KKU-097, KKU-466, and KKU-610, from the primary ...
Rattanaporn Jaidee, Apinya Jusakul, Piman Pocasap, Veerapol Kukongviriyapan, Laddawan Senggunprai, Auemduan Prawan, Watcharin Loilome, Attapol Titapun, Apiwat Jareanrat, Vasin Thanasukarn, Natcha Khuntikeo, Nisana Namwat, Yaovalux Chamgramol, Malinee Thanee, Phongsathorn Wichian, Jing Han Hong, Peiyong Guan, Hong Lee Heng, Chawalit Pairojkul, Bin Tean Teh, Sarinya Kongpetch   +20 more
doaj   +1 more source

Cholangiocarcinoma [PDF]

Visceral Medicine, 2016
Alfred, Königsrainer, Nisar P, Malek
openaire   +2 more sources

Combined hepatocellular cholangiocarcinoma (cHCC-CC): an update of genetics, molecular biology, and therapeutic interventions

, 2018
Chara Stavraka,1,* Hannah Rush,1,* Paul Ross1,2 1Department of Medical Oncology, Guy’s Cancer, Guy’s & St Thomas’ NHS Foundation Trust, London, UK; 2Department of Oncology, King’s College Hospital NHS Foundation Trust, London,
Ross P, Rush H, Stavraka C
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Aberrant DNA Methylation in Cholangiocarcinoma

, 2017
Cholangiocarcinoma is an epithelial malignancy arising in the region between the intrahepatic bile ducts and the ampulla of Vater at the distal end of the common bile duct. The effect of current chemotherapy regimens against cholangiocarcinoma is limited,
Toshiaki Nakaoka, Hidetsugu Saito, Yoshimasa Saito   +2 more
core   +1 more source

Heterogeneity Analyzed by CT‐Based Habitat Analysis for Clinical Management of Cancers: A Narrative Review

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tumors are highly heterogeneous, and whole‐lesion radiomics analysis is a popular method for extracting texture features that reflect this heterogeneity, which can be used to build models for cancer diagnosis, staging, therapy response evaluation, and prognosis prediction.
Yang Zhang, Zhi‐Yan Jin, Min‐Ying Lydia Su   +2 more
wiley   +1 more source

Obesity and cholangiocarcinoma

World Journal of Gastroenterology, 2013
It is estimated that about half of the population in developed countries are either overweight or obese. In some developing nations obesity rates have increased to surpass those seen in Western countries. This rate increase in obesity has many implications as obesity has been associated with numerous negative health effects including increased risks of
openaire   +2 more sources

Opisthorchiasis and cholangiocarcinoma in Southeast Asia: an unresolved problem

, 2017
Thomas Hughes,1,* Thomas O’Connor,1,* Anchalee Techasen,2,3 Nisana Namwat,2,3 Watcharin Loilome,2,3 Ross H Andrews,2–4 Narong Khuntikeo,3,5 Puangrat Yongvanit,3,6 Paiboon Sithithaworn,3,7 Simon D Taylor-Robinson1 1Division of Digestive Health,
Yongvanit P, Taylor-Robinson SD, Loilome W, Andrews RH, Khuntikeo N, Hughes T, Sithithaworn P, O'Connor T, Techasen A, Namwat N   +9 more
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Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Dual blockage of PI3K-mTOR and FGFR induced autophagic cell death in cholangiocarcinoma cells

Heliyon
Purpose: To assess the impact of concurrent inhibition of the FGFR and PI3K/mTOR signaling pathways on oncogenic characteristics in cholangiocarcinoma (CCA) cells, including proliferation, autophagy, and cell death.
Narumon Mahaamnad, Piman Pocasap, Veerapol Kukongviriyapan, Laddawan Senggunprai, Auemduan Prawan, Sarinya Kongpetch   +5 more
doaj   +1 more source

Predicting futility of upfront surgery in perihilar cholangiocarcinoma: Machine learning analytics model to optimize treatment allocation

Background: While resection remains the only curative option for perihilar cholangiocarcinoma, it is well known that such surgery is associated with a high risk of morbidity and mortality.
Perihilar Cholangiocarcinoma Collaboration Group
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