Results 121 to 130 of about 71,405 (265)
Opisthorchiasis and cholangiocarcinoma in Southeast Asia: an unresolved problem
, 2017 Thomas Hughes,1,* Thomas O’Connor,1,* Anchalee Techasen,2,3 Nisana Namwat,2,3 Watcharin Loilome,2,3 Ross H Andrews,2–4 Narong Khuntikeo,3,5 Puangrat Yongvanit,3,6 Paiboon Sithithaworn,3,7 Simon D Taylor-Robinson1 1Division of Digestive Health,
Yongvanit P +9 more
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Prototype of biliary drug-eluting stent with photodynamic and chemotherapy using electrospinning
, 2017 Background: The combination of biliary stent with photodynamic and chemotherapy seemed to be a beneficial palliative treatment of unresectable cholangiocarcinoma.
Chen, Min-Hua;Liang, Po-Chin;Chang, Kai-Chun;Huang, Jian-Yuan;Chang, Yu-Ting;Chang, Fuh-Yu;Wong, Jau-Min;Lin, Feng-Huei +1 more
core +1 more source
Oncology Inpatient Resuscitation Planning and Long‐Term “Rapid Response Call” Outcomes
Asia-Pacific Journal of Clinical Oncology, EarlyView.Optimal end‐of‐life care involves a patient‐centered approach. The dual audits presented in this study show that a proportion of oncology patients receiving palliative‐intent cancer treatment continue to be managed in hospital without a resuscitation plan and may undergo care escalation to a “rapid response” intervention despite poor prognosis ...
Dhanashree Tikhe +3 more
wiley +1 more source
Andrology, EarlyView.ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick +7 more
wiley +1 more source
A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics
Andrology, EarlyView.ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis +3 more
wiley +1 more source
Aberrant DNA Methylation in Cholangiocarcinoma
, 2017 Cholangiocarcinoma is an epithelial malignancy arising in the region between the intrahepatic bile ducts and the ampulla of Vater at the distal end of the common bile duct. The effect of current chemotherapy regimens against cholangiocarcinoma is limited,
Toshiaki Nakaoka +2 more
core +1 more source
Artificial Organs, EarlyView.Extracorporeal albumin dialysis (OPAL) effectively reduces bilirubin and improves other laboratory markers in posthepatectomy liver failure, particularly in secondary forms. It may serve as a bridging therapy to support hepatic recovery in critically ill patients, although prospective studies are needed to confirm its impact on survival.
Dorian Marckmann +16 more
wiley +1 more source
Background: While resection remains the only curative option for perihilar cholangiocarcinoma, it is well known that such surgery is associated with a high risk of morbidity and mortality.
Perihilar Cholangiocarcinoma Collaboration Group
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Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt
British Journal of Pharmacology, EarlyView.Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown +2 more
wiley +1 more source
Laparoscopic Resection of Hilar Cholangiocarcinoma
, 2012 Background: Surgical resection is the only curative treatment for hilar cholangiocarcinoma. Laparoscopic hepatectomy has been used to treat several types of liver neoplasms.
Machado, Marcel Autran C. +3 more
core +1 more source