Results 141 to 150 of about 79,213 (303)

Clinical Need and Research Investment for Liver Cancer in Australia

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Liver cancer incidence and mortality rates have been rising in comparison to other common cancers, but research funding has not been commensurate. ABSTRACT Aim This study aims to better understand factors driving the rising burden and costs of primary liver cancer (PLC) in Australia, identify key epidemiological trends, and ascertain investment in PLC ...
Romario Nguyen, Fatema Safri, Ankur Sharma, Jessica Howell, Stuart K. Roberts, Simone I. Strasser, Amany Zekry, Alan Wigg, Leon A. Adams, Michael Wallace, Golo Ahlenstiel, Eleonora Feletto, Karen Canfell, Tracey O'Brien, Jacob George, Liang Qiao   +15 more
wiley   +1 more source

Dual blockage of PI3K-mTOR and FGFR induced autophagic cell death in cholangiocarcinoma cells

Heliyon
Purpose: To assess the impact of concurrent inhibition of the FGFR and PI3K/mTOR signaling pathways on oncogenic characteristics in cholangiocarcinoma (CCA) cells, including proliferation, autophagy, and cell death.
Narumon Mahaamnad, Piman Pocasap, Veerapol Kukongviriyapan, Laddawan Senggunprai, Auemduan Prawan, Sarinya Kongpetch   +5 more
doaj   +1 more source

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick, Margaretha A. Skowron, Gereon Poschmann, Patrick Petzsch, Ann Kathrin Bergmann, Kai Stühler, Jochen Hecht, Daniel Nettersheim   +7 more
wiley   +1 more source

Perihilar cholangiocarcinoma: paradigms of surgical management.

, 2014
Cholangiocarcinoma is a lethal disease with increasing incidence worldwide. Perihilar cholangiocarcinoma represents the most common type of cholangiocarcinoma.
DeOliveira ML, Kambakamba P
core   +1 more source

Improvement of survival outcomes of cholangiocarcinoma by ultrasonography surveillance: Multicenter retrospective cohorts

Heliyon
Background: Most cholangiocarcinoma (CCA) patients present with late stage of disease because of the difficulty to diagnosis at an early stage, resulting in poor survival of CCA patients.
Nittaya Chamadol, Vallop Laopaiboon, Apiwat Jareanrat, Vasin Thanasukarn, Tharatip Srisuk, Vor Luvira, Poowanai Sarkhampee, Winai Ungpinitpong, Phummarat Khamvijite, Yutthapong Chumnanua, Nipath Nethuwakul, Passakorn Sodarat, Samrit Thammarit, Anchalee Techasen, Jaruwan Thuanman, Chaiwat Tawarungruang, Bandit Thinkhamrop, Prakasit Sa-Ngiamwibool, Watcharin Loilome, Piya Prajumwongs, Attapol Titapun   +20 more
doaj   +1 more source

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

Andrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis, Lisa Schneider, Felix Bremmer, Daniel Nettersheim   +3 more
wiley   +1 more source

Case report: Cholangiocarcinoma in a choledochal cyst

, 2008
Cholangiocarcinoma is a dreaded complication of unresected choledochal cysts, with an incidence approaching 20-30% in early adulthood. The risk of cholangiocarcinoma remains high where an internal drainage procedure has been performed and the cyst has ...
Vikas Rastogi, Arti Chaturvedi, JP Singh
core   +1 more source

Uses of Bovine Pericardium in General Surgery

ANZ Journal of Surgery, EarlyView.
Bovine pericardium is a versatile biologic material with expanding applications across general surgery. ABSTRACT Background Bovine pericardium (BP) is increasingly utilised in complex surgical reconstruction because of its favourable biological and mechanical properties.
William A. Ziaziaris, Makaela Bowman, Paul D. Morris, Kilian G. M. Brown, Michael J. Solomon, Jerome M. Laurence   +5 more
wiley   +1 more source

Photodynamic therapy for cholangiocarcinoma: overview and new developments

, 2009
PURPOSE OF REVIEW: Photodynamic therapy (PDT) with hematoporphyrins has emerged as promising treatment for nonresectable cholangiocarcinoma in several prospective observational studies and two randomized studies.
Ortner, Maria-Anna, Ortner MA, Ortner, Marianne, Maria-Anna Ortner   +3 more
core   +1 more source

Cost‐Effectiveness of Laparoscopic Common Bile Duct Exploration Versus Endoscopic Retrograde Cholangiopancreatography in Emergency Stone Management

ANZ Journal of Surgery, EarlyView.
Among 337 patients undergoing emergency management of common bile duct stones, laparoscopic common bile duct exploration was associated with lower healthcare costs, fewer procedures and shorter hospital stays than ERCP‐based management, supporting single‐stage surgical management as a safe and cost‐effective treatment strategy.
Tess Howard, Lily Owens, Harendra Maneesha De Silva, Darren Lowen, David Bird, Russell Hodgson   +5 more
wiley   +1 more source