Results 111 to 120 of about 76,116 (300)

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Staging laparoscopy for cholangiocarcinoma [PDF]

, 2008
The precise role of laparoscopic assessment of biliary tract malignancy is yet to be defined. The evidence for its use has been reviewed to establish the role of laparoscopy for preoperative staging of cholangiocarcinoma.
Garden, O.J., Connor, S., Garden, O. J., Joseph, S.   +3 more
core   +1 more source

Transcriptome changes of liver fluke Opisthorchis viverrini in diabetic hamsters

Parasite
A recent study in hamsters showed that infection with the liver fluke Opisthorchis viverrini in diabetic hosts worsens the severity of hepatobiliary disease.
Chaidee Apisit, Charoenram Naruechar, Sengthong Chatchawan, Dangtakot Rungtiwa, Pinlaor Porntip, Pongking Thatsanapong, Pinlaor Somchai   +6 more
doaj   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Network pharmacology- and cell-based assessments identify the FAK/Src pathway as a molecular target for the antimetastatic effect of momordin Ic against cholangiocarcinoma

Heliyon
Previous studies have indicated the efficacy of momordin Ic (MIc), a plant-derived triterpenoid, against several types of cancers, implying its potential for further development.
Piman Pocasap, Auemduan Prawan, Sarinya Kongpetch, Laddawan Senggunprai   +3 more
doaj   +1 more source

Modulating Hallmarks of Cholangiocarcinoma [PDF]

, 2018
How are cholangiocarcinoma cells different from non-malignant cholangiocytes? All of the hallmarks of cancer apply- those reported in this dissertation include cell proliferation, migration, apoptosis, and evasion of growth suppression.
Wehrkamp, Cody
core  

Precision medicine in cholangiocarcinoma

, 2018
Cholangiocarcinoma is one of the epithelial cancers with the poorest prognosis and the narrowest therapeutic choice in humans. Compared with other cancer types, cholangiocarcinoma has been often neglected by oncology and liver research studies, thereby ...
PELLINO, ANTONIO, Guido, Maria, Fabris, Luca, Fassan, Matteo, Dadduzio, Vincenzo, Cillo, Umberto, Indraccolo, Stefano, Loupakis, Fotios, Cadamuro, Massimiliano   +8 more
core   +1 more source

From MyACR to MyμAlbumin: Clinical Validation of a High‐Precision, Real‐Time Immunoturbidimetric PoC Device for Early Chronic Kidney Disease Detection

Journal of Clinical Laboratory Analysis, EarlyView.
The MyμAlbumin device is a high‐precision, real‐time immunoturbidimetric point‐of‐care tool for rapid quantification of urinary albumin, designed to improve early detection of chronic kidney disease (CKD). Clinical validation with 138 patients demonstrated exceptional diagnostic accuracy, achieving a sensitivity of 99.11% and specificity of 98.23 ...
Tullayakorn Plengsuriyakarn, Wanna Chaijaroenkul, Napaporn Youngvises, Kridsada Sirisabhabhorn, Waraporn Bubpha, Kesara Na‐Bangchang   +5 more
wiley   +1 more source

Heterochronous Adrenal Metastasis from Intrahepatic Cholangiocarcinoma: Report of a Case

, 2014
We herein report a case of laparoscopic adrenalectomy for solitary adrenal metastasis from intrahepatic cholangiocarcinoma (ICC). Although the treatment of extrahepatic metastasis from primary liver tumors is essentially palliative, solitary metastasis ...
Adachi, Tomohiko, Maruya, Yasuhiro, Okamoto, Tatsuya, Kuroki, Tamotsu, Abe, Kuniko, Kanematsu, Takashi, Eguchi, Susumu   +6 more
core