Results 111 to 120 of about 96,828 (293)

Inhibition of -type amino acid transporter 1 activity as a new therapeutic target for cholangiocarcinoma treatment

Tumor Biology, 2017
Unlike normal cells, cancer cells undergo unlimited growth and multiplication, causing them to require massive amounts of amino acid to support their continuous metabolism. Among the amino acid transporters expressed on the plasma membrane, l- type amino
Supak Yothaisong, Hasaya Dokduang, Naohiko Anzai, Keitaro Hayashi, Nisana Namwat, Puangrat Yongvanit, Sakkarn Sangkhamanon, Promsuk Jutabha, Hitoshi Endou, Watcharin Loilome   +9 more
doaj   +1 more source

Overexpression of a panel of cancer stem cell markers enhances the predictive capability of the progression and recurrence in the early stage cholangiocarcinoma

Journal of Translational Medicine, 2020
Background Cancer recurrence is the important problem of cholangiocarcinoma (CCA) patients, lead to a very high mortality rate. Therefore, the identification of candidate markers to predict CCA recurrence is needed in order to effectively manage the ...
Sureerat Padthaisong, Malinee Thanee, Nisana Namwat, Jutarop Phetcharaburanin, Poramate Klanrit, Narong Khuntikeo, Attapol Titapun, Sakkarn Sungkhamanon, Hideyuki Saya, Watcharin Loilome   +9 more
doaj   +1 more source

Cuproptosis‐Related Genes in Immune Infiltration and Diagnosis in Hepatitis B Virus‐Related Acute Liver Failure

Exploration, EarlyView.
The role of cuproptosis in HBV‐ALF was explored via bioinformatics and liver biopsy tissues. There are some crosstalks among cuproptosis, immune infiltration, and ferroptosis (The figure was created by Bio Render). ABSTRACT Hepatitis B virus (HBV) infection poses a significant challenge to global health, particularly in developing countries such as ...
Jingwen Deng, Tao Zhu, Yueyang Wang, Sitong Zhang, Hong Deng, Guilan Quan, Tingting Peng, Chuanbin Wu, Huiqiang Cai, Chao Lu, Xiaopeng Cai   +10 more
wiley   +1 more source

Ureteropelvic junction obstruction caused by metastatic cholangiocarcinoma [PDF]

, 2019
We describe the rare case of a 61-year-old female with right ureteropelvic junction (UPJ) obstruction caused by metastatic cholangiocarcinoma. Her past medical history was notable for cholangiocarcinoma treated with neoadjuvant chemoradiation and two ...
Figenshau, Robert S, Pickersgill, Nicholas A, Wright, Alec J   +2 more
core   +1 more source

Different Pattern of Treatment Failure After Chemoradiation Between p16+ and p16− Patients Affected by Oropharyngeal Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Oropharyngeal cancer (OPC) exhibits distinct clinical behaviors according to HPV/p16 status and smoking exposure. While HPV‐positive OPC generally shows superior survival, differences in recurrence patterns remain unclear. Methods A retrospective multicenter analysis of 674 AJCC VII edition Stage III–IVa/b OPC patients treated with ...
Riccardo Gili, Paolo Bossi, Luca Lalli, Lisa Francesca Linda Licitra, Marta Maddalo, Almalina Bacigalupo, Liliana Belgioia, Jon Cacicedo, Nadia Facchinetti, Almudena Garcia Castano, Marc Oliva, Pierluigi Bonomo, Giuseppe Sanguineti, Pierfrancesco Franco, Athanassios Argiris, Amanda Psyrri, Ester Orlandi   +16 more
wiley   +1 more source

Hilar cholangiocarcinoma

World Journal of Gastrointestinal Oncology, 2013
Hilar cholangiocarcinoma (HC) is a rare tumor. It accounts for 2/3 of the tumors of the biliary tract. Untreated, prognosis is very poor. Surgery is the only therapy that offers the possibility of cure but is technically very complex. With recent improvements in the therapeutic strategies applied by multidisciplinary teams, survival rates in the ...
openaire   +2 more sources

Indoleamine 2,3-dioxygenase 1 expression predicts cholangiocarcinoma patient survival

Experimental and Molecular Pathology
Background: Cholangiocarcinoma (CCA) is a prevalent hepatobiliary disease in northeast Thailand, where late diagnosis and limited treatment options contribute to poor prognosis.
Mallika Naeklang, Hasaya Dokduang, Piya Prajumwongs, Poramate Klanrit, Arporn Wangwiwatsin, Nisana Namwat, Attapol Titapun, Prakasit Sa-Ngiamwibool, Watcharin Loilome   +8 more
doaj   +1 more source

Prolonged oxidative stress down-regulates Early B cell factor 1 with inhibition of its tumor suppressive function against cholangiocarcinoma genesis

Redox Biology, 2018
Early B cell factor 1 (EBF1) is a transcription factor involved in the differentiation of several stem cell lineages and it is a negative regulator of estrogen receptors. EBF1 is down-regulated in many tumors, and is believed to play suppressive roles in
Napat Armartmuntree, Mariko Murata, Anchalee Techasen, Puangrat Yongvanit, Watcharin Loilome, Nisana Namwat, Chawalit Pairojkul, Chadamas Sakonsinsiri, Somchai Pinlaor, Raynoo Thanan   +9 more
doaj   +1 more source

Viability of Non-Coplanar VMAT for Liver SBRT as Compared to Coplanar VMAT and Beam Orientation Optimized 4π IMRT. [PDF]

, 2016
PurposeThe 4π static non-coplanar radiotherapy delivery technique has demonstrated better normal tissue sparing and dose conformity than the clinically used volumetric modulated arc therapy (VMAT).
Cao, Minsong, Lee, Percy, Nguyen, Dan, Niu, Tianye, Sheng, Ke, Tran, Angelia, Woods, Kaley, Yu, Victoria Y   +7 more
core   +1 more source

Incorporation of Microsatellite Instability and Tumor-Infiltrating Lymphocytes in Opisthorchis viverrini-Associated Cholangiocarcinoma: Predicting Patient Outcomes

Journal of Molecular Pathology
Background: Cholangiocarcinoma (CCA) has the highest incidence in Northeastern Thailand, where patients generally present with late diagnosis and poor prognosis.
Natcha Khuntikeo, Apiwat Jareanrat, Vasin Thanasukarn, Tharatip Srisuk, Vor Luvira, Watcharin Loilome, Poramate Klanrit, Anchalee Techasen, Jarin Chindaprasirt, Prakasit Sa-Ngiamwibool, Chaiwat Aphivatanasiri, Sureerat Padthaisong, Piya Prajumwongs, Attapol Titapun   +13 more
doaj   +1 more source