Results 101 to 110 of about 79,213 (303)

Prognostic Determinants of Overall Survival After Resection for Pancreatic Ductal Adenocarcinoma: A Consensus‐Based Conceptual Framework

Journal of Surgical Oncology, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) carries a dismal prognosis despite surgical resection, yet the prognostic literature remains fragmented across hundreds of single‐institution studies that vary in design, covariates, and analytical approaches.
Muhammad Maisam Ali, Kaleem S. Ahmed, Clayton T. Marcinak, Syed Ali Tayyeb Hasan, Anne D. Letocha, Noorain Ahmad, Haider bin Khalid, Kainat Fatima, Syed Nabeel Zafar   +8 more
wiley   +1 more source

Discovery of novel serum peptide biomarkers for cholangiocarcinoma recurrence through MALDI-TOF MS and LC–MS/MS peptidome analysis

Scientific Reports
Cholangiocarcinoma (CCA) is an aggressive cancer originating from bile duct epithelial cells, with a high rate of recurrence following surgical resection. Recurrence is categorized as early linked to aggressive tumor biology than late recurrence.
Vasin Thanasukarn, Piya Prajumwongs, Nattha Muangritdech, Watcharin Loilome, Nisana Namwat, Poramate Klanrit, Arporn Wangwiwatsin, Sawanya Charoenlappanit, Janthima Jaresitthikunchai, Sittiruk Roytrakul, Attapol Titapun   +10 more
doaj   +1 more source

Inhibition of -type amino acid transporter 1 activity as a new therapeutic target for cholangiocarcinoma treatment

Tumor Biology, 2017
Unlike normal cells, cancer cells undergo unlimited growth and multiplication, causing them to require massive amounts of amino acid to support their continuous metabolism. Among the amino acid transporters expressed on the plasma membrane, l- type amino
Supak Yothaisong, Hasaya Dokduang, Naohiko Anzai, Keitaro Hayashi, Nisana Namwat, Puangrat Yongvanit, Sakkarn Sangkhamanon, Promsuk Jutabha, Hitoshi Endou, Watcharin Loilome   +9 more
doaj   +1 more source

Comparative Diagnostic Sensitivity of Endoscopic Ultrasound-guided Tissue Acquisition for Hepatocellular Carcinoma Versus Intrahepatic Cholangiocarcinoma. [PDF]

DEN Open
ABSTRACT Background and Aims Accurate histological differentiation between hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) is essential for selecting appropriate treatment. Endoscopic ultrasound‐guided tissue acquisition (EUS‐TA) is increasingly used for focal liver lesions; however, comparative data on its diagnostic ...
Takano Y, Tamai N, Noda J, Azami T, Niiya F, Uyama R, Maruoka N, Yamagami T, Nakamura A, Ogawa T, Umemoto T, Nagahama M.   +11 more
europepmc   +2 more sources

Epidemiology of cholangiocarcinoma

European Journal of Surgical Oncology
Cholangiocarcinoma (CCA) represents a heterogenous set of malignancies arising from the biliary tract. Classification of CCA subdivides tumours into intrahepatic (iCCA) and extrahepatic (eCCA), with eCCA further categorised as perihilar (pCCA) and distal (dCCA) lesions. Tumour subtypes show distinct epidemiological, genetic and clinical characteristics.
Maria Qurashi, Mathew Vithayathil, Shahid A. Khan   +2 more
openaire   +2 more sources

Outcomes Following Total Pancreatectomy With and Without Vascular Resection: A NSQIP Analysis Comparing Trends in Patient Selection and Outcomes Over 5 Years

Journal of Surgical Oncology, EarlyView.
ABSTRACT Introduction Advances in neoadjuvant therapy and surgical techniques have led to more total pancreatectomies (TP) with vascular resection for pancreatic cancer. This study assesses contemporary outcomes of TP with venous (VR) and arterial (AR) resections compared to non‐vascular resection (NVR).
Zofia Czarnecka, Kevin Verhoeff, A. M. James Shapiro, Chaya Shwaartz   +3 more
wiley   +1 more source

Aberrant DNA Methylation in Cholangiocarcinoma

, 2017
Cholangiocarcinoma is an epithelial malignancy arising in the region between the intrahepatic bile ducts and the ampulla of Vater at the distal end of the common bile duct. The effect of current chemotherapy regimens against cholangiocarcinoma is limited,
Toshiaki Nakaoka, Hidetsugu Saito, Yoshimasa Saito   +2 more
core   +1 more source

Heterogeneity Analyzed by CT‐Based Habitat Analysis for Clinical Management of Cancers: A Narrative Review

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tumors are highly heterogeneous, and whole‐lesion radiomics analysis is a popular method for extracting texture features that reflect this heterogeneity, which can be used to build models for cancer diagnosis, staging, therapy response evaluation, and prognosis prediction.
Yang Zhang, Zhi‐Yan Jin, Min‐Ying Lydia Su   +2 more
wiley   +1 more source

TCGA cholangiocarcinoma analysis

, 2019
Supplementary data for the TCGA cholangiocarcinoma data ...
Nitish Mishra (6030875)
core   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source