Results 101 to 110 of about 76,116 (300)

Management of Intrahepatic Cholangiocarcinoma

, 2021
Cholangiocarcinoma is a tumor that arises as a result of differentiation of the cholangiocytes and can develop from anywhere in the biliary tree. Subtypes of cholangiocarcinoma are differentiated based on their location in the biliary tree.
Akshay Shetty, Sudha Kodali, David W. Victor, Rafik M. Ghobrial, Soumya Shekhar   +4 more
core   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Detection of Lymph Node Metastasis Using PET/CT in Cholangiocarcinoma

, 2007
We herein describe a 71-year-old female case of cholangiocarcinoma. Computed tomography of the abdomen showed an infiltrating lesion with low attenuation and a dilatation of the intrahepatic bile duct in the lateral segment of the liver.
Minami, Shigeki, Suga, Kazuo, Furukawa, Masato, Inokuma, Takamitsu, Chiba, Kenya   +4 more
core  

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Overexpression of a panel of cancer stem cell markers enhances the predictive capability of the progression and recurrence in the early stage cholangiocarcinoma

Journal of Translational Medicine, 2020
Background Cancer recurrence is the important problem of cholangiocarcinoma (CCA) patients, lead to a very high mortality rate. Therefore, the identification of candidate markers to predict CCA recurrence is needed in order to effectively manage the ...
Sureerat Padthaisong, Malinee Thanee, Nisana Namwat, Jutarop Phetcharaburanin, Poramate Klanrit, Narong Khuntikeo, Attapol Titapun, Sakkarn Sungkhamanon, Hideyuki Saya, Watcharin Loilome   +9 more
doaj   +1 more source

Comparative Diagnostic Sensitivity of Endoscopic Ultrasound-guided Tissue Acquisition for Hepatocellular Carcinoma Versus Intrahepatic Cholangiocarcinoma. [PDF]

DEN Open
ABSTRACT Background and Aims Accurate histological differentiation between hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) is essential for selecting appropriate treatment. Endoscopic ultrasound‐guided tissue acquisition (EUS‐TA) is increasingly used for focal liver lesions; however, comparative data on its diagnostic ...
Takano Y, Tamai N, Noda J, Azami T, Niiya F, Uyama R, Maruoka N, Yamagami T, Nakamura A, Ogawa T, Umemoto T, Nagahama M.   +11 more
europepmc   +2 more sources

Current update on combined hepatocellular-cholangiocarcinoma [PDF]

, 2014
Combined hepatocellular-cholangiocarcinoma is a rare but unique primary hepatic tumor with characteristic histology and tumor biology. Recent development in genetics and molecular biology support the fact that combined hepatocellular-cholangiocarcinoma ...
Manjiri K. Dighe, Puneet Bhargava, Neeraj Lalwani, Dighe, Manjiri K., Yeh, Matthew M., Dhakshina Moorthy Ganeshan, Ganeshan, Dhakshina Moorthy, Orpheus Kolokythas, Shanbhogue, Alampady K., Maximin, Suresh, Suresh Maximin, Bhargava, Puneet, Alampady K. Shanbhogue, Matthew M. Yeh, Lalwani, Neeraj, Kolokythas, Orpheus   +15 more
core   +1 more source

Adjuvant Chemotherapy Regimens in Resected Biliary Tract Cancers: National, Comparative, Observational Study (TOG/GI‐SAFRADJU‐2501)

International Journal of Cancer, EarlyView.
ABSTRACT The recommended adjuvant chemotherapy (adj‐ChT) regimen for resected biliary tract cancers (BTC) is capecitabine (Cape); yet, the recommendation is based on limited evidence. Although varied adj‐ChTs have been employed in practice, robust real‐world data is scarce. We conducted a national, multicenter, hospital‐based registry study to evaluate
Erman Akkus, Mehmet Kayaalp, Müzeyyen Aslı Ergözoğlu, Ilgın Koç Kuş, Doğan Bayram, Bilgeşah Kılıçtaş, Emel Ayvaz Güneyin, Ali Kalem, Haydar Temizyürek, Mehmet Mutlu Çatlı, Mehmet Sinan Akarca, Maral Martin Mıldanoğlu, Görkem Turhan, Mahmut Kara, Hacı Arak, Feyza Arslan Tan, Burak Paçacı, Berkay Yeşilyurt, Orhun Akdoğan, Emine Bihter Çetin, Selahattin Çelik, Fatma Keskin Uzundere, Elif Şahin, Zehra Sadak Öcal, Lamia Şeker Can, Bahadır Köylü, Mehmet Cem Fidan, Esmanur Kaplan Tüzün, Teoman Şakalar, Elif Sertesen Çamöz, Haydar Çağatay Yüksel, Onur Yazdan Balçık, Pınar Peker, Mehmet Yılmaz, Şeymanur Ala Enli, Erdem Kölemen, Sibel Oyucu Orhan, Yakup Düzköprü, Mustafa Ersoy, Tuğba Akın Telli, Mesut Yılmaz, Yusuf İlhan, Atila Yıldırım, Ramazan Coşar, Müslih Ürün, Arif Hakan Önder, Murat Araz, Ertuğrul Bayram, Havva Yeşil Çınkır, Ali Alkan, Mustafa Gürbüz, Nilüfer Avcı, Fatma Paksoy Türköz, İsmail Oğuz Kara, Fatih Köse, İlkay Tuğba Ünek, Ahmet Bilici, Öznur Bal, Şuayib Yalçın, Lorenza Rimassa, Hatime Arzu Yaşar   +60 more
wiley   +1 more source

The Circulating Cholangiocarcinoma Protein Biomarkers CRP and MASP2 Also Predict Gallbladder Cancer Risk

International Journal of Cancer, EarlyView.
ABSTRACT In a recent publication, Lapitz et al. reported differences in serum levels that predict the development of cholangiocarcinoma (CCA) in patients with primary sclerosing cholangitis prior to clinical manifestation. We examined whether these biomarkers also predict the risk of gallbladder cancer (GBC) in European prospective plasma samples from ...
Linda Zollner, Jeroen Krijgsveld, Dominique Scherer, Justo Lorenzo Bermejo, on behalf of the EULAT Eradicate GBC Consortium   +4 more
wiley   +1 more source

Impact of Molecular Alterations on Survival in Biliary Tract Cancers: A Retrospective Belgian Cohort Study

International Journal of Cancer, EarlyView.
ABSTRACT Biliary tract cancers (BTCs) are aggressive malignancies associated with a poor prognosis. Although molecular profiling is recommended to guide therapeutic decision‐making, real‐practice data on the prevalence and prognostic significance of genomic alterations in European BTC cohorts remain limited.
Jorine Arnouts, Léon C. van Kempen, Senada Koljenović, Helena Oliveres, Pieterjan Vanclooster, Hans Prenen, Caro De Weerdt, Siddharth Chhajlani, Geert Roeyen, Laure Sorber, Koen De Winne, Jonas Dahnoun, Greetje Vanhoutte, Timon Vandamme, Karen Zwaenepoel   +14 more
wiley   +1 more source