Targeting Cholangiocarcinoma Cells By Cold Piezoelectric Plasmas: In Vitro Efficacy And Cellular Mechanisms [PDF]
Scientific Reports, Vol. 14, 30178, pp. 16 (2024)Cold piezoelectric plasma (CPP) is a novel approach in cancer therapy, enabling the development of portable treatment devices capable of triggering cancer cell death. While its effectiveness remains underexplored, this research focuses on its application against cholangiocarcinoma (CCA), an aggressive cancer of the biliary tract.
arxiv +1 more source
The roles of transforming growth factor-β, Wnt, Notch and hypoxia on liver progenitor cells in primary liver tumours [PDF]
, 2014 Primary liver tumours have a high incidence and mortality. The most important forms are hepatocellular carcinoma and intrahepatic cholangiocarcinoma, both can occur together in the mixed phenotype hepatocellular-cholangiocarcinoma. Liver progenitor cells
Bogaerts, Eliene +4 more
core +1 more source
Phase II Study of BGJ398 in Patients With FGFR-Altered Advanced Cholangiocarcinoma.
Journal of Clinical Oncology, 2017 Purpose No standard treatment exists for patients with cholangiocarcinoma for whom first-line gemcitabine-based therapy fails. Fibroblast growth factor receptor 2 ( FGFR2) fusions/translocations are present in 13% to 17% of intrahepatic ...
M. Javle +28 more
semanticscholar +1 more source
Gut microbiome directs hepatocytes to recruit MDSC and promote cholangiocarcinoma.
Cancer Discovery, 2020 Gut dysbiosis is commonly observed in patients with cirrhosis and chronic gastrointestinal disorders, however, its effect on anti-tumor immunity in the liver is largely unknown.
Qian-fei Zhang +30 more
semanticscholar +1 more source
Imaging of Cholangiocarcinoma [PDF]
Visceral Medicine, 2016 Cholangiocarcinoma (CC) is the second most common primary hepatobiliary tumour, and it is increasing in incidence. Imaging characteristics, behaviour, and therapeutic strategies in CC differ significantly, depending on the morphology and location of the tumour.
Konstantin Nikolaou +5 more
openaire +3 more sources
β-caryophyllene and low-doses of doxorubicin against liver cancer cells: a “metronomic chemotherapy” [PDF]
, 2017 Cholangiocarcinoma and hepatocellular carcinoma are primary liver cancers, both representing a growing challenge due to their increasing morbidity and mortality.
Abete, Lorena +7 more
core +4 more sources
Infectious Diseases of Poverty, 2019 Background Opisthorchis viverrini infection is highly prevalent in northeast Thailand. This liver fluke is classified as a carcinogen due to its causal links with cholangiocarcinoma (CCA) development.
Kavin Thinkhamrop +7 more
doaj +1 more source
Characterisation of the immune-related transcriptome in resected biliary tract cancers [PDF]
, 2017 Although biliary tract cancers (BTCs) are known to have an inflammatory component, a detailed characterisation of immune-related transcripts has never been performed.
Braconi, Chiara +19 more
core +3 more sources
Anatomical, histomorphological and molecular classification of cholangiocarcinoma
Liver international (Print), 2019 Cholangiocarcinoma constitutes a heterogeneous group of malignancies that can emerge at any point of the biliary tree. Cholangiocarcinoma is classified into intrahepatic, perihilar and distal based on its anatomical location. Histologically, conventional
T. Kendall +6 more
semanticscholar +1 more source
Diagnosis of cholangiocarcinoma [PDF]
HPB, 2008 Cholangiocarcinoma is suspected based on signs of biliary obstruction, abnormal liver function tests, elevated tumor markers (carbohydrate antigen 19-9 and carcinoembryonic antigen), and ultrasonography showing a bile stricture or a mass, especially in intrahepatic cholangiocarcinoma.
openaire +3 more sources