Results 1 to 10 of about 35,855 (199)

Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases [PDF]

, 2020
In the past ten years, our understanding of the importance of bile acids has expanded from fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for amelioration of chronic cholestatic liver diseases.
Alpini, Gianfranco, Francis, Heather, Kennedy, Lindsey, Kundu, Debjyoti, Meadows, Vik   +4 more
core   +1 more source

The natural history of primary sclerosing cholangitis in 781 children. A multicenter, international collaboration [PDF]

, 2017
There are limited data on the natural history of primary sclerosing cholangitis (PSC) in children. We aimed to describe the disease characteristics and long-term outcomes of pediatric PSC.
Abdou, Reham, Alqoaer, Khaled, Amin, Mansi, Amir, Achiya Z, Auth, Marcus, Bazerbachi, Fateh, Broderick, Annemarie, Chan, Albert, Cotter, Jillian, Deneau, Mark R, Doan, Sylvia, El-Matary, Wael, El-Youssef, Mounif, Ferrari, Federica, Furuya, Katryn N, Gottrand, Frederic, Gottrand, Madeleine, Gupta, Nitika, Homan, Matjaz, Iorio, Raffaele, Jensen, M K, Kamath, Binita M, Kolho, Kaija-Leena, Konidari, Anastasia, Koot, Bart, Ledder, Oren, Mack, Cara, Martinez, Mercedes, Miloh, Tamir, Mo Kim, Kyung, Mohan, Parvathi, O'Cathain, Niamh, Papadopoulou, Alexandra, Ricciuto, Amanda, Sathya, Pushpa, Saubermann, Lawrence, Shteyer, Eyal, Smolka, Vratislav, Tanaka, Atushi, Valentino, Pamela L, Varier, Raghu, Venkat, Veena, Vitola, Bernadette, Vos, Miriam B, Woynarowski, Marek, Yap, Jason   +45 more
core   +6 more sources

Clinical Features and Risk Factors of Autoimmune Liver Involvement in Pediatric Inflammatory Bowel Disease [PDF]

, 2016
OBJECTIVES:Autoimmune liver disease is reported in up to 7.8% of children with inflammatory bowel disease. A distinct inflammatory bowel disease phenotype has been suggested in adults and in small pediatric cohorts.
Alexopoulou, Alvarez, Block, Boonstra, Deneau, Dotson, Faubion, Feldstein, Goyal, Gregorio, Halliday, Hirschfield, Hov, Jose, Jose, Levine, Levine, Liberal, Loftus, Loftus, Lundqvist, Maggiore, Malaty, Mieli-Vergani, Navaneethan, Noble-Jamieson, Olsson, Ordonez, Penna, Rönnblom, Sokol, Zholudev   +31 more
core   +1 more source

The gut microbiota, bile acids and their correlation in primary sclerosing cholangitis associated with inflammatory bowel disease. [PDF]

, 2018
BACKGROUND: Patients with primary sclerosing cholangitis associated with inflammatory bowel disease (PSC-IBD) have a very high risk of developing colorectal neoplasia.
Bao, X, Brito, H, Moura-Santos, P, Oliveira, A, et al., Palmela, C, Ruiqi, H, Silva, J, Torres, J   +7 more
core   +1 more source

Development of colon cancer after liver transplantation for primary sclerosing cholangitis associated with ulcerative colitis [PDF]

, 1990
Between February 26, 1981, and July 30, 1987, 36 patients underwent orthotopic liver transplantation for primary sclerosing cholangitis associated with ulcerative colitis.
Higashi, H, Kakizoe, S, Marsh, JW, Starzi, TE, Tzakis, A, Yanaga, K   +5 more
core   +1 more source

The incidence of portal vein thrombosis at liver transplantation [PDF]

, 1992
The incidence of portal vein thrombosis was examined in 885 patients who received orthotopic liver transplantations for various end‐stage liver diseases between 1989 and 1990. The thrombosis was classified into four grades.
Iwatsuki, S, Nonami, T, Starzl, TE, Yokoyama, I   +3 more
core   +1 more source

Identification of a serum biomarker panel for the differential diagnosis of cholangiocarcinoma and primary sclerosing cholagnitis [PDF]

, 2018
The non-invasive differentiation of malignant and benign biliary disease is a clinical challenge. Carbohydrate antigen 19-9 (CA19-9), leucine-rich α2-glycoprotein (LRG1), interleukin 6 (IL6), pyruvate kinase M2 (PKM2), cytokeratin 19 fragment (CYFRA21.1)
Blyuss, O, Cuenco, J, Dawnay, A, Kazarian, A, Manns, MP, Menon, U, Pereira, SP, Timms, JF, Wehnert, N, Whitwell, HJ   +9 more
core   +2 more sources

Does ursodeoxycholic acid change the proliferation of the colorectal mucosa? A randomized, placebo-controlled study [PDF]

, 2003
Background: In animal models ursodeoxycholic acid (UDCA) showed a chemoprotective effect against colon cancer. To explain this, a reduced proliferation of the colorectal mucosal proliferation was suggested.
Diebold, J., Göke, B., Hay, U., Marsteller, I., Ochsenkühn, Thomas, Paumgartner, Gustav, Sackmann, M.   +6 more
core   +1 more source

Serum micrornas as novel biomarkers for primary sclerosing cholangitis and cholangiocarcinoma [PDF]

, 2016
The diagnosis of primary sclerosing cholangitis (PSC) is difficult due to the lack of sensitive and specific biomarkers, as is the early diagnosis of cholangiocarcinoma (CC), a complication of PSC.
Alpini, Gianfranco, Alvaro, Domenico, Bernuzzi, Francesca, Bowlus, Christopher L, Carbone, Marco, Eric Gershwin, M, He, Xiao Song, Invernizzi, Pietro, Lleo, Ana, Locati, Massimo, Marabita, Francesco, Marzioni, Marco, Mirolo, Massimiliano, Muri Boberg, Kirsten, Piscaglia, Fabio, Rimassa, Lorenza, Torzilli, Guido, Yang, Guo Xiang   +17 more
core   +2 more sources

Prognostic value of thyroid hormone levels in patients evaluated for liver transplantation [PDF]

, 1985
The thyroid hormones T4, T3, rT3 and TSH were assayed in 134 adult patients evaluated and accepted as potential liver transplant candidates at the Universty of Pittsburgh from March, 1981 to December, 1983.
Carter, Chopra, Chopra, Fleiss, Hepner, Inada, Israel, Jennings, Kaptein, Klachko, McConnon, National Institutes of Health Concensus Development Conference Statement, Normura, Robbins, Schenker, Schussler, Slag, Starzl, Van Thiel, Van Thiel, Walfish   +20 more
core   +1 more source