Results 21 to 30 of about 40,327 (258)
Current Opinion in Gastroenterology, 2007 Primary sclerosing cholangitis is a chronic cholestatic liver disease characterized by strictures of the biliary tree complicated by cirrhosis and cholangiocarcinoma. It is immune mediated, although the precise aetiology remains unknown.Research into etiopathogenesis and epidemiology, diagnosis of cholangiocarcinoma, associations with inflammatory ...
Maggs, JR, Chapman, R
openaire +3 more sources
Primary sclerosing cholangitis
Medicine, 1984 Primary sclerosing cholangitis (PSC) is a chronic, cholestatic liver disease caused by diffuse inflammation and fibrosis that can involve the entire biliary tree. The progressive pathological process obliterates intrahepatic and extrahepatic bile ducts, leading ultimately to biliary cirrhosis, portal hypertension and hepatic failure.
E R, Dickson, N F, LaRusso, R H, Wiesner
openaire +5 more sources
Development of colon cancer after liver transplantation for primary sclerosing cholangitis associated with ulcerative colitis [PDF]
, 1990 Between February 26, 1981, and July 30, 1987, 36 patients underwent orthotopic liver transplantation for primary sclerosing cholangitis associated with ulcerative colitis.
Higashi, H +5 more
core +1 more source
Peribiliary glands are key in regeneration of the human biliary epithelium after severe bile duct injury [PDF]
, 2019 Peribiliary glands (PBG) are a source of stem/progenitor cells organized in a cellular network encircling large bile ducts. Severe cholangiopathy with loss of luminal biliary epithelium has been proposed to activate PBG, resulting in cell proliferation ...
Carpino, Guido +15 more
core +6 more sources
Pembrolizumab Induced Sclerosing Cholangitis: Why You Need a Liver Biopsy
Case Reports in Oncology, 2023 The advent of checkpoint inhibitor immunotherapy has rapidly changed the landscape of the management of cancers. However, its use has also been associated with the rise of immunotherapy-related adverse effects (irAEs).
Ian Liang +2 more
doaj +1 more source
Liver involvement in pediatric celiac disease [PDF]
, 2015 Celiac disease (CD) is an intestinal inflammatory disease that manifests in genetically susceptible individuals when exposed to dietary gluten. It is a common chronic disorder, with a prevalence of 1% in Europe and North America.
Anania, Caterina +4 more
core +1 more source
Rapid Progression of Primary Sclerosing Cholangitis Complicated with Ulcerative Colitis
Case Reports in Gastrointestinal Medicine, 2015 Primary sclerosing cholangitis is a cholestatic condition with unknown etiology and long-standing, progressive course, leading to cirrhosis and requiring orthotropic liver transplant. In approximately 80%, primary sclerosing cholangitis is accompanied by
Piotr Pardak +2 more
doaj +1 more source
Case of nivolumab-induced sclerosing cholangitis: lessons from long-term follow-up
BMJ Open Gastroenterology, 2020 Nivolumab is an immune checkpoint inhibitor used to treat multiple solid-organ malignancies. While many of its immune-related adverse events are well established, nivolumab-induced sclerosing cholangitis remains poorly characterised, with no defined ...
Wanyuan Cui +4 more
doaj +1 more source
Journal of Translational Autoimmunity, 2021 Takayasu arteritis and primary sclerosing cholangitis are two rare disorders. The pathogenesis of Takayasu arteritis involves immune-mediated mechanisms, and corticosteroids represent the mainstay for treatment.
Giacomo Mulinacci +4 more
doaj +1 more source
Identification of a serum biomarker panel for the differential diagnosis of cholangiocarcinoma and primary sclerosing cholagnitis [PDF]
, 2018 The non-invasive differentiation of malignant and benign biliary disease is a clinical challenge. Carbohydrate antigen 19-9 (CA19-9), leucine-rich α2-glycoprotein (LRG1), interleukin 6 (IL6), pyruvate kinase M2 (PKM2), cytokeratin 19 fragment (CYFRA21.1)
Blyuss, O +9 more
core +2 more sources