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Clinical Presentation, Cholangiographic Features, Natural History, and
Outcome: A Series of 16 Cases [PDF]
, 2015 Secondary sclerosing cholangitis in critically ill patients (SSC-CIP) is an
important differential diagnosis in patients presenting with cholestasis and
PSC-like cholangiographic changes in endoscopic retrograde cholangiography
(ERC).Adler, Andreas, Eurich, Dennis, Faber, Wladimir, Leonhardt, Silke, Neuhaus, Peter, Schott, Eckart, Seehofer, Daniel, Veltzke-Schlieker, Wilfried +7 morecore +1 more sourceCoccidioidomycosis Prophylaxis in Liver, Kidney, and Heart Transplant Recipients Residing in Endemic Areas Within the United States
Transplant Infectious Disease, Volume 27, Issue 2, March/April 2025.Our data suggests that abdominal organ transplant recipients residing in CM‐endemic areas with no prior CM exposure may not require CM prophylaxis. Therefore, we recommend implementing a shared decision‐making model among healthcare providers and patients for this lower‐risk patient population.Faiza Morado, Roland Davoudi, Rachel Cartus, Pnada Kawewat‐Ho, Apurva Akkad, Suhail A. Shaikh +5 morewiley +1 more sourceSecondary sclerosing cholangitis in patients suffering cardiogenic shock
ESC Heart Failure, Volume 12, Issue 3, Page 2239-2244, June 2025.Abstract Aims
Cardiogenic shock (CS) patients suffer from severe organ hypoperfusion, yet the incidence of secondary sclerosing cholangitis in critically ill patients (SSC‐CIP) in CS is poorly described. Given the limited evidence and severity of this syndrome, we aimed to further investigate SSC‐CIP in the context of CS.Hugo Lanz, Clemens Scherer, Philipp Kasper, Christoph Adler, Leonhard Binzenhöfer, Sabine Hoffmann, Julia Höpler, Marie Kraft, Nils Gade, Raúl Nicolás Jamin, Ruben Evertz, Daniel Hoyer, Jörn Tongers, Christian Schulze, Christian Jung, Julia Claus, Janine Pöss, Lisa Crusius, Norman Mangner, Christian Hagl, Georg Nickenig, Sebastian Zimmer, Steffen Massberg, Holger Thiele, Franz Haertel, Enzo Lüsebrink +25 morewiley +1 more sourceEmerging Links Between Ferroptosis and Neurodegeneration: Implications for Disease Mechanisms and Nutraceutical Interventions
Food Science &Nutrition, Volume 13, Issue 6, June 2025.Ferroptosis, a controlled cell death, is driven by iron and characterized by reactive oxygen species and lipid peroxidation. The impact of lipid peroxides, GSH/GPX4, and iron metabolism–targeting small molecule inhibitors is discussed. Nucleic acids, proteins, and phytochemicals are implicated as inhibitors of ferroptosis.Anwar Ali, Quratulain Babar, Ayesha Saeed, Domenico Sergi, Nenad Naumovski, Isam A. Mohamed Ahmed, Ghalia Shamlan, Halah Abdulrahman Hafiz, Muhammad Faisal Manzoor, Joanna Trafialek, Felix Kwashie Madilo +10 morewiley +1 more sourceAccurate and precise in vivo liver 3D T1 mapping at 3T
Magnetic Resonance in Medicine, Volume 93, Issue 6, Page 2331-2345, June 2025.Abstract Purpose
To develop an accurate and precise liver 3D T1$$ {T}_1 $$ mapping method using only scanner‐agnostic sequences. Methods
While the spoiled gradient‐recalled echo sequence is widely available on clinical scanners, variable flip angle T1$$ {T}_1 $$ mapping methods based on this sequence provide biased T1$$ {T}_1 $$ estimates, with the ...Gabriela Belsley, Ferenc E. Mózes, Damian J. Tyler, Matthew D. Robson, Elizabeth M. Tunnicliffe +4 morewiley +1 more sourceTreatment and outcome of gall bladder leiomyoma in an asymptomatic dog
Veterinary Record Case Reports, Volume 13, Issue 2, June 2025.Abstract
The purpose of this report was to describe the diagnostic protocol, treatment and outcome of an 11‐year‐old, entire male, mixed‐breed dog with a gall bladder neoplasia histologically consistent with a leiomyoma. On referral, the patient had no clinical signs related to the gall bladder mass.Elisa Pizzi, Stefano Zanardi, Andrea Renzi, Ilaria Maga, Sara Del Magno +4 morewiley +1 more sourceClinical Trial: A Multicentre Randomised Controlled Trial of Carvedilol Versus Variceal Band Ligation in Primary Prevention of Variceal Bleeding in Liver Cirrhosis (CALIBRE Trial)
Alimentary Pharmacology &Therapeutics, Volume 61, Issue 11, Page 1740-1754, June 2025.There is no evidence of a difference between carvedilol 12.5 mg daily and VBL in the primary prevention of variceal bleeding in patients with cirrhosis and medium‐to large‐sized oesophageal varices. Carvedilol has no untoward safety concerns, is well tolerated, cost‐saving and potentially cost‐effective and is the preferred first‐line primary ...Dhiraj Tripathi, Kelly Handley, Lisa Holden, Zainab Abdali, Sue Jowett, Jonathan Mathers, Christopher Poyner, Paul Richardson, James Ferguson, Ian Rowe, CALIBRE trial collaborative group, Ashis Mukhopadhya, Jennifer Cathcart, Pauline Dundas, Oluyemi Solanke, Siby Joseph, Cyril Sieberhagen, Melanie Harrison, Claire Burston, Gavin Wright, Princess Gabiana, Aimee Williams, Bushena Miyesa, John Ramage, Hayley Cousins, Rachel Bryant, Sim L. Lim, Janisha Patel, Mel Penacerrada, Rachel Lorusso, Rory McCorry, Allison Lloyd, Heather Lawther, Safa Al‐Shamma, Anna Maria Wilce, Sulleman Moreea, Carol Firth, Robert Przemioslo, Charlotte Cranfield, Joanna Leithead, Gwilym Webb, Victoria Snowdon, Aarani Mahalingam, Abigail Ford, Thomas Pembroke, Sarah Harrhy, Fiona Greaves, Matthew Foxton, Carina Bautista, Esther Unitt, Susan Dale, Andrew Austin, Catherine Addleton, Sharan Shetty, Rizwan Mahmood, Clare Allcock, Karen Reid, Michael Miller, Anne Elliott, Leanne Cosgrove, Shona Murray, Francisco Porra Pérez, Melanie Kent, Marie Callaghan, Dina Mansour, Ann Wilson, Adrian Stanley, Alexis Duncan, Lauren Walker, Coral Hollywood, Paula Hiltout, Phil Berry, Jessica Cordle, Andrew King, Laurence Hopkins, Faye Moore, Mirriam Sangombe, Lynsey Corless, Tania Nurun, Julie Wilcox, Bethia Featherstone, Ameet Dhar, Maria Lanoria, Gary Hahn, Brian Hogan, Mark McPhail, Matthew M. Farrant, Nicola Griffiths, Ane Zamalloa, Victoria Appleby, Mark Aldersley, Rebecca Bishop, Louise Clark, Farooq Khan, Ka‐Kit Li, Olivia Watchorn, John Hutchinson, Patricia Kane, Julie Burton, Stephanie Lupton, Jacqui Bartholomew, Emma‐Jane Stoner, Steven Masson, Sarah Hogg, Simon Rushbrook, Vanessa Martin, Tom Lee, Jane Luke, Angela Green, Stephen Ryder, Preethi Shibu, Jeremy Cobbold, Loren Smith, Lou Holland, Eleni Rountenko, Matthew Cramp, Alex Parkinson, Richard Aspinall, Emily Jones, Jincy Daniels, Anu Andrews, Hyder Hussaini, Lisa Trembath, Fiona Hammonds, Ben Hudson, Rob James, Raj Mookerjee, Christine Eastgate, Gloria Ferrariz, Abigail Brownlie, Dai Samuel, Bethan Deacon, Imran Patanwala, Edward Britton, Callum Wood, Martina Lofthouse, Giovanna Bretland, Vikram Sharma, Louise Payaniandy, James Hand, Graham Branagan, Aqueel Jamil, Alpha Anthony, Louise Bell, Ahmed Abu‐Shanab, Samia Hussain, Manjinder Gohel, Charlie Millson, Kerry Elliott, Tania Neale, Laura Harrison, Barbara Hoeroldt, Ihteshamul Haq, Angela Liaros, Holly Caborn, Ulrich Thalheimer, Kate Winstance, Darren Craig, Julie Tregonning, Janisha Patel, Helen Stone, Lijamol Joseph, Jisha Jacob, Joanne Topping, Peter Murphy, Jill Effard, Sarah Hughes, Criscel Jan Pelaez, Rohit Sinha, Jenny Henderson, Jagdish Nagaraj, Chin Lye Ch’Ng, Caradog Thomas, Elaine Brinkworth, Moby Joseph, Andrew Claridge, James Neale, Camille Walling, Maggie Ryder, Jacinta Ugoji, Neil Rajoriya, Emma Burke, Nishant Gautam, Julie Fletcher, Richard Keld, Philip Paterson, Christopher Corbett, Marie Green, Siobhan Sutton, Naomi Gott, Peter Hayes, Peter Devine, Khaled Ahmed, Kate Brailsford, Peter Brocklehurst, Margaret Grant, Gemma Slinn, Matthew Soden, Rebecca Amos‐Hirst, Hannah Bensoussane, Catherine Moakes, Bhushan Chhajed, Paul Riley, Neil Winkles, Lazaros Andronis, Christel McMullan +205 morewiley +1 more sourceLongitudinal Relationship Between Elevated Liver Biochemical Tests and Negative Clinical Outcomes in Primary Biliary Cholangitis: A Population‐Based Study
Alimentary Pharmacology &Therapeutics, Volume 61, Issue 11, Page 1775-1784, June 2025.We investigated whether longitudinal monitoring of multiple liver biochemistries and serum‐based non‐invasive fibrosis scores provides prognostic value in patients with primary biliary cholangitis. Our findings indicate that prolonged elevation of multiple hepatic biomarkers and serum‐based non‐invasive fibrosis scores is associated with an increased ...Kris V. Kowdley, David W. Victor III, Joanna P. MacEwan, Radhika Nair, Alina Levine, Jennifer Hernandez, Leona Bessonova, Jing Li, Darren Wheeler, Gideon Hirschfield +9 morewiley +1 more source