Results 131 to 140 of about 40,327 (258)

A case report of immune checkpoint inhibitor‐related myositis and cholangitis induced by pembrolizumab

open access: yesClinical Case Reports
Key Clinical Message Rare but severe, immune‐related adverse events such as myositis and sclerosing cholangitis can occur with immune checkpoint inhibitors in lung cancer treatment.
Takafumi Yamano   +3 more
doaj   +1 more source

Association Between Oral Lichen Planus and Non‐Oral Cancers: A Multicentre Case–Control SIPMO Study

open access: yesOral Diseases, EarlyView.
ABSTRACT Objectives This multicentre case–control study aimed to investigate the potential association between oral lichen planus (OLP) and extraoral cancers. The secondary objective included the identification of risk factors for this association. Methods The study was conducted between January 2023 and June 2024 and included 21 Italian Oral Medicine ...
Gioele Gioco   +62 more
wiley   +1 more source

The role of neutrophils in the pathophysiology of inflammatory bowel diseases

open access: yesPeriodontology 2000, EarlyView.
Abstract Objectives Inflammatory bowel disease (IBD) encompasses a spectrum of chronic disorders of the gastrointestinal tract, with a potential bidirectional relationship with periodontitis. Neutrophils are key regulators of immune‐inflammatory responses and play a major role in both diseases.
Joao Paulo Steffens   +8 more
wiley   +1 more source

ARC in Critical Ill OLT Recipients: True Prevalence, Risk Factors, and Impact on Early Aggressive PK/PD Target Non‐Attainment of CI Beta‐Lactam Therapy for Posttransplant Gram‐Negative Infections

open access: yesTransplant Infectious Disease, EarlyView.
Augmented renal clearance (ARC) represents a quite prevalent condition among critical orthotopic liver transplant recipients (23.2%). ARC is associated with different demographics and clinical features and significantly affects the attainment of aggressive beta‐lactams pharmacokinetic/pharmacodynamic targets despite the administration of standard ...
Milo Gatti   +6 more
wiley   +1 more source

Efficiency and Safety of Endoscopic Injection Sclerotherapy With Ligation for Esophageal Varices: A Retrospective Study.

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Endoscopic injection sclerotherapy with ligation (EISL) is a combined endoscopic treatment that involves endoscopic injection sclerotherapy (EIS) and endoscopic variceal ligation. This study aimed to compare the efficacy of conventional EIS and EISL in treating esophageal varices and the usefulness of EISL.
Keita Maki   +6 more
wiley   +1 more source

IgG4-related autoimmune disease : imaging findings [PDF]

open access: yes, 2013
IgG4 autoimmune disease (or hyper IgG4 disease) is a relatively recently described systemic disease that is characterised by abundant infiltration of IgG4-positive plasma cells and lymphocytes with associated fibrosis leading to organ dysfunction ...
Vassallo, Pierre
core  

Building a Robust Investigator‐Initiated Platform: The I‐CARE Experience

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1537-1546, June 2026.
Investigator‐initiated studies that include information collected by patients are rising, but limited data is available on patient and investigator experience in this setting. The I‐CARE cohort included patients with inflammatory bowel disease (IBD) monthly collecting clinical information in 15 countries for up to 6 years.
Julien Kirchgesner   +906 more
wiley   +1 more source

Primary Sclerosing Cholangitis from Childhood to Adult Age : Risk Factors, Monitoring and Outcome [PDF]

open access: yes, 2017
BACKGROUND AND AIM This thesis includes two studies conducted in a paediatric and two studies conducted in an adult primary sclerosing cholangitis (PSC) population.
Tenca, Andrea
core  

Systemic Drivers and Molecular Mechanisms of Sarcopenia in Aetiology‐Specific End‐Stage Liver Disease

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Patients with end‐stage liver disease (ESLD) often present with sarcopenia, defined as loss of skeletal muscle mass and quality, which is associated with reduced quality of life and increased mortality. However, the molecular mechanisms driving sarcopenia in ESLD are not fully understood and there are currently no therapeutic ...
Thomas Nicholson   +16 more
wiley   +1 more source

Molecular Quantification of Fibrogenesis and Macrophage Activation Associate With Clinical Worsening in Patients With Cirrhosis

open access: yesLiver International Communications, Volume 7, Issue 2, June 2026.
ABSTRACT Knowledge of the potential of biomarkers for monitoring clinical improvement, assessing trajectory or disease progression in advanced chronic liver disease is still insufficient. This study investigated biomarkers of fibrosis and macrophage activation over time in newly diagnosed patients with cirrhosis and their potential association with ...
Emilie Toft Skovgaard   +8 more
wiley   +1 more source

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