Results 151 to 160 of about 40,327 (258)
JPGN Reports, Volume 7, Issue 2, Page 366-369, May 2026.Abstract Pancreatic and biliary tract injuries from blunt abdominal trauma are rare in children. Common bile duct (CBD) strictures secondary to pancreatic trauma are even more uncommon, and management traditionally involves surgery. We report a 9‐year‐old boy who developed a severe distal intrapancreatic CBD stricture after blunt pancreatic trauma ...
Alexis M. Woida +2 more
wiley +1 more source
JPGN Reports, Volume 7, Issue 2, Page 370-373, May 2026.Abstract Infantile exocrine pancreatic insufficiency is a rare condition, most often encountered in the context of cystic fibrosis or Shwachman–Diamond syndrome. The SPINK1 gene encodes a trypsin inhibitor protein that prevents the premature activation of digestive enzymes in pancreatic tissue.
France Chalon +10 more
wiley +1 more source
Primary sclerosing cholangitis [PDF]
Hepatology, 1999 P, Angulo, K D, Lindor
openaire +2 more sources
Liver Fibrosis: Molecular Pathogenesis and Therapeutic Interventions
MedComm, Volume 7, Issue 5, May 2026.We systematically summarized the etiologies, diagnostic approaches, and pathogenic mechanisms of liver fibrosis. Also, the therapeutic interventions for liver fibrosis were systematically classified into two main categories: etiological treatment and mechanism‐based antifibrotic therapies.
Jiaorong Qu +8 more
wiley +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.ABSTRACT Elafibranor 80 mg/day is approved for second‐line primary biliary cholangitis (PBC) treatment. We present pharmacokinetic (PK) analyses of elafibranor and its metabolite, GFT1007, and pharmacokinetic‐pharmacodynamic (PKPD) analyses describing the relationship between their exposure and responses in alkaline phosphatase (ALP) and total ...
Qing Xi Ooi +5 more
wiley +1 more source
United European Gastroenterology Journal, Volume 14, Issue 4, May 2026.ABSTRACT Background Upadacitinib (UPA) is the first oral Janus kinase (JAK) inhibitor approved for the treatment of Crohn's disease (CD). Real‐world data, particularly from large nationwide cohorts, remain limited. This study aimed to evaluate the real‐world effectiveness, safety, and treatment persistence of UPA in patients with CD.
M. Iborra +51 more
wiley +1 more source
Safety of Immune Checkpoint Inhibitors Prior to Liver Transplantation in Hepatocellular Carcinoma
Alimentary Pharmacology &Therapeutics, Volume 63, Issue 10, Page 1369-1379, May 2026.Patients who received immune checkpoint inhibitors before liver transplant for the treatment of hepatocellular carcinoma had rejection and survival outcomes comparable to those without ICI exposure. Most rejection episodes were effectively managed with medical therapy.
L. Aceituno +21 more
wiley +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3895-3902, May 2026.Abstract Background The effects of aspirin on hepatic steatosis and fibroinflammation are unclear. The study aimed to examine the association between aspirin use and liver magnetic resonance imaging (MRI)‐derived liver fat and corrected T1 (cT1). Methods We used UK Biobank imaging cohort data.
Qi Feng +4 more
wiley +1 more source
Diagnostic and Prognostic Values of Bile Biomarkers for Malignant Biliary Stenosis
Liver International, Volume 46, Issue 5, May 2026.ABSTRACT Introduction Differentiating between malignant and benign biliary strictures remains a clinical challenge because current diagnostic tools have limited sensitivity. The detection of tumour‐related biomarkers directly in bile, which is in close contact with the lesion, may enhance diagnostic accuracy.
E. Gigante +9 more
wiley +1 more source