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Baillière's Clinical Gastroenterology, 1997
Primary sclerosing cholangitis (PSC) is a chronic, progressive cholestatic liver disease whose aetiopathogenesis is unknown. PSC is frequently associated with inflammatory bowel disease, in particular chronic ulcerative colitis, is most commonly observed in young males and is clinically characterized by fatigue, pruritus and jaundice.
P J, Marotta, N F, LaRusso, R H, Wiesner
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Primary sclerosing cholangitis (PSC) is a chronic, progressive cholestatic liver disease whose aetiopathogenesis is unknown. PSC is frequently associated with inflammatory bowel disease, in particular chronic ulcerative colitis, is most commonly observed in young males and is clinically characterized by fatigue, pruritus and jaundice.
P J, Marotta, N F, LaRusso, R H, Wiesner
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Current Opinion in Gastroenterology, 2002
Primary sclerosing cholangitis in children can mimic autoimmune hepatitis in the absence of inflammatory bowel disease. Most adult patients have been identified with human leukocyte antigens that either predispose or protect against disease. Novel class I alleles and cytokine polymorphisms may also contribute to disease susceptibility.
Jayant A, Talwalkar, Keith D, Lindor
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Primary sclerosing cholangitis in children can mimic autoimmune hepatitis in the absence of inflammatory bowel disease. Most adult patients have been identified with human leukocyte antigens that either predispose or protect against disease. Novel class I alleles and cytokine polymorphisms may also contribute to disease susceptibility.
Jayant A, Talwalkar, Keith D, Lindor
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Secondary Sclerosing Cholangitis: A Comparison to Primary Sclerosing Cholangitis
The American Journal of Gastroenterology, 2005The natural history of secondary sclerosing cholangitis (SSC) is ill-defined. In order to better determine the natural history of this condition, we retrospectively reviewed data from the Mayo Clinic in Rochester, Minnesota. We also compared the natural history of patients diagnosed with SSC to a cohort with a diagnosis of primary sclerosing ...
Andrea A, Gossard +2 more
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Primary sclerosing cholangitis
The American Journal of Surgery, 1987Primary sclerosing cholangitis was seen in only 7 of 6,494 biliary operations performed between 1948 and 1979. Fifteen more cases were seen in 1,467 biliary operations performed over a recent 5 year period. Surgery was directed primarily towards the differential diagnosis between cholangiocarcinoma and primary sclerosing cholangitis of the upper bile ...
T T, White, M J, Hart
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Primary sclerosing cholangitis
The American Journal of Surgery, 1971Abstract Primary sclerosing cholangitis is an uncommon condition of unknown etiology, presenting extrahepatic biliary obstruction due to a chronic inflammatory obliterative process. Criteria for diagnosis include progressive biliary obstruction due to a chronic inflammatory fibrous process, absence of biliary stones, absence of biliary surgery prior ...
A W, Perry +3 more
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Primary Sclerosing Cholangitis
Endoscopy, 1985Primary sclerosing cholangitis was diagnosed in 6 patients (4 men and 2 women), with ages ranging from 33 to 71 years. Four of them had ulcerative colitis, with an evolution from 8 to 21 years, the other two had Crohn's disease with 2 and 3 years of evolution.
A D, Jorge, C, Esley
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Secondary sclerosing cholangitis
Nature Reviews Gastroenterology & Hepatology, 2009Secondary sclerosing cholangitis (SSC) is a chronic cholestatic biliary disease, characterized by inflammation, obliterative fibrosis of the bile ducts, stricture formation and progressive destruction of the biliary tree that leads to biliary cirrhosis.
Petra, Ruemmele +2 more
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Sclerosing cholangitis in children
The Journal of Pediatrics, 1994We report on 56 children with sclerosing cholangitis (SC) seen between 1972 and 1992. The first symptoms occurred at a mean age of 3.7 years; 15 infants had neonatal cholestatic jaundice. At diagnosis, cholestatic jaundice was present in 25 children, hepatomegaly in 54, splenomegaly in 41, and ascites in 12.
D, Debray +4 more
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Sclerosing cholangitis in childhood
The Journal of Pediatrics, 19802. Pollock HM, and Dahlgren BJ: Distribution of streptococcal groups in clinical specimens in evaluation of bacitracin screening, Appl Microbiol 27:I41, 1974. 3. Sprunt K, Vail D, and Asnes RS: Identification of streptococcus pyogenes in a pediatric outpatient department, Pediatrics 54:718, 1974. 4.
S L, Werlin +3 more
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