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Secondary sclerosing cholangitis
Nature Reviews Gastroenterology & Hepatology, 2009Secondary sclerosing cholangitis (SSC) is a chronic cholestatic biliary disease, characterized by inflammation, obliterative fibrosis of the bile ducts, stricture formation and progressive destruction of the biliary tree that leads to biliary cirrhosis.
Petra, Ruemmele +2 more
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Primary sclerosing cholangitis
The Lancet, 2018Primary sclerosing cholangitis is a rare, chronic cholestatic liver disease characterised by intrahepatic or extrahepatic stricturing, or both, with bile duct fibrosis. Inflammation and fibrosis of bile ducts and the liver are followed by impaired bile formation or flow and progressive liver dysfunction.
Dyson JK +4 more
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Primary Sclerosing Cholangitis
New England Journal of Medicine, 1995Y M, Lee, M M, Kaplan
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Baillière's Clinical Gastroenterology, 1997
Primary sclerosing cholangitis (PSC) is a chronic, progressive cholestatic liver disease whose aetiopathogenesis is unknown. PSC is frequently associated with inflammatory bowel disease, in particular chronic ulcerative colitis, is most commonly observed in young males and is clinically characterized by fatigue, pruritus and jaundice.
P J, Marotta, N F, LaRusso, R H, Wiesner
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Primary sclerosing cholangitis (PSC) is a chronic, progressive cholestatic liver disease whose aetiopathogenesis is unknown. PSC is frequently associated with inflammatory bowel disease, in particular chronic ulcerative colitis, is most commonly observed in young males and is clinically characterized by fatigue, pruritus and jaundice.
P J, Marotta, N F, LaRusso, R H, Wiesner
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Current Opinion in Gastroenterology, 2002
Primary sclerosing cholangitis in children can mimic autoimmune hepatitis in the absence of inflammatory bowel disease. Most adult patients have been identified with human leukocyte antigens that either predispose or protect against disease. Novel class I alleles and cytokine polymorphisms may also contribute to disease susceptibility.
Jayant A, Talwalkar, Keith D, Lindor
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Primary sclerosing cholangitis in children can mimic autoimmune hepatitis in the absence of inflammatory bowel disease. Most adult patients have been identified with human leukocyte antigens that either predispose or protect against disease. Novel class I alleles and cytokine polymorphisms may also contribute to disease susceptibility.
Jayant A, Talwalkar, Keith D, Lindor
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Primary sclerosing cholangitis
The American Journal of Surgery, 1987Primary sclerosing cholangitis was seen in only 7 of 6,494 biliary operations performed between 1948 and 1979. Fifteen more cases were seen in 1,467 biliary operations performed over a recent 5 year period. Surgery was directed primarily towards the differential diagnosis between cholangiocarcinoma and primary sclerosing cholangitis of the upper bile ...
T T, White, M J, Hart
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Primary sclerosing cholangitis
The American Journal of Surgery, 1971Abstract Primary sclerosing cholangitis is an uncommon condition of unknown etiology, presenting extrahepatic biliary obstruction due to a chronic inflammatory obliterative process. Criteria for diagnosis include progressive biliary obstruction due to a chronic inflammatory fibrous process, absence of biliary stones, absence of biliary surgery prior ...
A W, Perry +3 more
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Primary Sclerosing Cholangitis
Endoscopy, 1985Primary sclerosing cholangitis was diagnosed in 6 patients (4 men and 2 women), with ages ranging from 33 to 71 years. Four of them had ulcerative colitis, with an evolution from 8 to 21 years, the other two had Crohn's disease with 2 and 3 years of evolution.
A D, Jorge, C, Esley
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Primary sclerosing cholangitis
Current Treatment Options in Gastroenterology, 2001There is no proven medical therapy for primary sclerosing cholangitis. The goal of management should be treatment of symptoms and complications of cholestasis, as well as attempts at treating the underlying disease process. In addition, efforts should be made to recognize and treat or prevent the known complications of primary sclerosing cholangitis ...
Young-Mee, Lee, David J., Kim
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Primary sclerosing cholangitis
Gastroenterology Nursing, 2007Primary sclerosing cholangitis is a chronic cholestatic liver disease of unknown origin characterized by progressive inflammation, destruction, and fibrosis of the intrahepatic and extrahepatic bile ducts. The disease leads to obliteration of intrahepatic bile ducts and to biliary cirrhosis, end-stage liver disease, and portal hypertension.
A.J. SMALL, N.F. LARUSSO, K.N. LAZARIDIS
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