Results 231 to 240 of about 40,327 (258)
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Primary Sclerosing Cholangitis
Inflammatory Bowel Diseases, 2005Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by inflammation and fibrosis of the intra- and extrahepatic bile ducts. An estimated 80% of patients in North America and Europe have coexistent inflammatory bowel disease (IBD). The underlying pathophysiology of PSC remains poorly understood.
Jayant A, Talwalkar, Keith D, Lindor
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Primary sclerosing cholangitis
Current Problems in Surgery, 1992Primary sclerosing cholangitis is a condition of unknown cause. It is recognized by liver dysfunction and its characteristic radiologic appearance, which is related to portal tract inflammation, bile duct proliferation, and periductal fibroses involving small intrahepatic and large extrahepatic ducts.
F M, Martin, J W, Braasch
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Primary Sclerosing Cholangitis
Archives of Internal Medicine, 1982Recent investigations have clarified the clinical, radiologic, and pathologic features of primary sclerosing cholangitis, a chronic fibrosing disorder affecting the biliary tree. This progressive, cholestatic biliary disease is diagnosed when an elevated serum alkaline phosphatase level and stricturing and beading of bile ducts on cholangiography are ...
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Primary Sclerosing Cholangitis
Southern Medical Journal, 1978Two new cases of primary sclerosing cholangitis with a rapid fatal course, particularly the patient in Case 2, are presented. Primary sclerosing cholangitis is a rare condition of unknown cause presenting with extrahepatic biliary obstruction due to a chronic inflammatory obliterative process with the absence of stones, cancer, or previous biliary ...
M, Maleki, M, Faghihi, M, Golshan
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Localized Sclerosing Cholangitis?
Endoscopy, 1985Primary sclerosing cholangitis presenting as a localized stricture affecting a segment of the extrahepatic biliary tree is seldom found. This article describes the case of a 56-year-old male admitted with obstructive jaundice, in whom endoscopic retrograde cholangiography showed a localized and smooth stricture at the common hepatic duct, initially ...
J, Panés +4 more
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Primary sclerosing cholangitis
Clinics in Liver Disease, 2004Primary sclerosing cholangitis is a cholestatic liver disease strongly associated with IBD. Considerable advances in the understanding of its pathogenesis have been made. The idea of autoimmunity affecting genetically susceptible individuals is largely accepted; however, much remains to be explained about the origin of this disease.
Flavia D, Mendes, Keith D, Lindor
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Primary Sclerosing Cholangitis
Surgical Clinics of North America, 1981In spite of an improved understanding of the etiology of primary sclerosing cholangitis, which supports the use of immunosuppressive therapy with steroids and azathioprine, these pharmacologic manipulations have not altered the ultimate outcome of the disease. Drainage remains the most accepted mode of therapy when possible.
L F, Williams, D J, Schoetz
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The microbiota and the gut–liver axis in primary sclerosing cholangitis
Nature Reviews Gastroenterology and Hepatology, 2022Johannes Roksund Hov, Tom H Karlsen
exaly

