Results 11 to 20 of about 52,579 (265)

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

Hepatology, EarlyView., 2022
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr, Benedikt Kaufmann, Maria Eugenia Inzaugarat, Theresa Maria Holtmann, Lukas Geisler, Jana Hundertmark, Marlene Sophia Kohlhepp, Laela M. Boosheri, Daisy R. Chilin‐Fuentes, Amanda Birmingham, Kathleen M. Fisch, Joel D. Schilling, Sven H. Loosen, Christian Trautwein, Christoph Roderburg, Münevver Demir, Frank Tacke, Hal M. Hoffman, Ariel E. Feldstein, Alexander Wree   +19 more
wiley   +1 more source

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei in a liver-transplanted patient: a case report

World Journal of Surgical Oncology, 2018
Background Diagnostic work-ups in transplanted immunosuppressed patients are a challenge as non-specific findings may be interpreted as transplant-related complications. If the disease in question is rare and slowly developing like pseudomyxoma peritonei
Ebbe Billmann Thorgersen, Espen Melum, Trine Folseraas, Stein Gunnar Larsen, Pål Dag Line   +4 more
doaj   +1 more source

Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy

Hepatology, EarlyView., 2022
Serum bile acid levels predict outcomes in patients with biliary atresia who achieve normalized bilirubin levels after Kasai portoenterostomy. Abstract Background and Aims In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP).
Sanjiv Harpavat, Kieran Hawthorne, Kenneth D. R. Setchell, Monica Narvaez Rivas, Lisa Henn, Charlotte A. Beil, Saul J. Karpen, Vicky L. Ng, Estella M. Alonso, Jorge A. Bezerra, Stephen L. Guthery, Simon Horslen, Kathy M. Loomes, Patrick McKiernan, John C. Magee, Robert M. Merion, Jean P. Molleston, Philip Rosenthal, Richard J. Thompson, Kasper S. Wang, Ronald J. Sokol, Benjamin L. Shneider, for Childhood Liver Disease Research Network (ChiLDReN)   +22 more
wiley   +1 more source

The changing faces of cholangitis [version 1; referees: 2 approved]

F1000Research, 2016
A variety of diseases are included under the umbrella term ‘cholangitis’, including hepatobiliary diseases with an autoimmune pathogenesis (such as primary sclerosing cholangitis, primary biliary cholangitis, and IgG4-associated sclerosing cholangitis ...
Sum P. Lee, Joseph R. Roberts, Rahul Kuver   +2 more
doaj   +1 more source

Characteristics of the Gut Microbiome and IL-13/TGF-β1 Mediated Fibrosis in Post-Kasai Cholangitis of Biliary Atresia

Frontiers in Pediatrics, 2021
Aims: Cholangitis in biliary atresia (BA), which accelerates liver fibrosis progression, is among the most common serious complications after Kasai surgery; however, its etiology remains elusive.
Lingdu Meng, Jia Liu, Junfeng Wang, Min Du, Shouhua Zhang, Yanlei Huang, Zhen Shen, Rui Dong, Gong Chen, Shan Zheng   +9 more
doaj   +1 more source

THE ROLE OF ENDOTHELIAL DYSFUNCTION IN THE PATHOGENESIS OF LIVER FAILURE IN OBSTRUCTIVE JAUNDICE OF BENIGN ORIGIN

Паёми Сино, 2022
Objective: To study the role of endothelial dysfunction in the pathogenesis of liver failure (LF) in obstructive jaundice of benign origin (OJBO). Methods: The study was based on the analysis of the results of a clinical examination of 68 patients ...
M.K. GULOV, K.R. RUZIBOYZODA, S.M. ABDULLOZODA, B.I. SAFAROV   +3 more
doaj   +1 more source

Difficulties in Diagnosing Isolated IgG4-associated Sclerosing Cholangitis

Journal of Digestive Endoscopy, 2019
The most common causes of recurrent cholangitis are biliary stones and neoplasia. Primary types of sclerosing cholangitis such as IgG4-associated sclerosing cholangitis (IgG4-SC) and primary sclerosing cholangitis (PSC) are rare causes of recurrent ...
Gábor Zsóri, Dóra Illés, László Tiszlavicz, László Czakó   +3 more
doaj   +1 more source

Dilatation of the Proximal Cystic Duct: Is It a Variant to “Type VI” Choledochal Cyst? [PDF]

Journal of Clinical and Diagnostic Research, 2016
Choledochal cysts are rare congenital malformations, comprising of dilatation of the biliary tree of different localization. Classically, classification of choledochal cysts describes five variants of the disease.
Christos Kaselas, Dimitrios Patoulias, Ioannis Patoulias, Ioannis Spyridakis   +3 more
doaj   +1 more source

Sclerosing cholangitis

Current Opinion in Gastroenterology, 1995
Primary sclerosing cholangitis is a chronic cholestatic liver disease of unknown etiology. Immunogenetic factors are considered important in its pathogenesis. The genetic susceptibility to primary sclerosing cholangitis is associated, in part, with the HLA HLA-DRB1, DQA1, DQB1 haplotype.
Martins, E, Chapman, R
openaire   +6 more sources

Early cholangitis after portoenterostomy in children with biliary atresia

Journal of Indian Association of Pediatric Surgeons, 2019
Aims and Objectives: Biliary atresia (BA) is a cholangiodestructive disease of the biliary tree. The first line of treatment is a Kasai portoenterostomy (PE) following which patients may develop cholangitis.
Priya Ramachandran, Mohamed Safwan, Muthukrishnan Saravana Balaji, Ashitha K Unny, Anis Akhtarkhavari, Vidya Tamizhvanan, Mohamed Rela   +6 more
doaj   +1 more source