Results 31 to 40 of about 101,142 (261)

Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis.

Journal of Hepatology, 2021
BACKGROUND&AIMS Primary sclerosing cholangitis (PSC) is characterized by chronic inflammation and progressive fibrosis of the biliary tree. The bile acid receptor TGR5 is found on biliary epithelial cells (BECs), where it promotes secretion ...
M. Reich, L. Spomer, C. Klindt, Katharina Fuchs, J. Stindt, K. Deutschmann, J. Höhne, E. Liaskou, J. Hov, T. Karlsen, U. Beuers, J. Verheij, Sofía Ferreira-González, G. Hirschfield, S. Forbes, C. Schramm, I. Esposito, D. Nierhoff, P. Fickert, C. Fuchs, M. Trauner, María García-Beccaria, G. Gabernet, S. Nahnsen, Jan-Philipp Mallm, M. Vogel, K. Schoonjans, Tobias Lautwein, K. Köhrer, D. Häussinger, T. Luedde, M. Heikenwalder, V. Keitel   +32 more
semanticscholar   +1 more source

The efficacy of a novel integrated outside biliary stent and nasobiliary drainage catheter system for acute cholangitis: a single center pilot study [PDF]

Clinical Endoscopy, 2023
Background/Aims Endoscopic biliary drainage is the gold standard treatment for cholangitis. The two methods of biliary drainage are endoscopic biliary stenting and nasobiliary drainage.
Naosuke Kuraoka, Tetsuro Ujihara, Hiromi Kasahara, Yuto Suzuki, Shun Sakai, Satoru Hashimoto   +5 more
doaj   +1 more source

Difficulties in Diagnosing Isolated IgG4-associated Sclerosing Cholangitis

Journal of Digestive Endoscopy, 2019
The most common causes of recurrent cholangitis are biliary stones and neoplasia. Primary types of sclerosing cholangitis such as IgG4-associated sclerosing cholangitis (IgG4-SC) and primary sclerosing cholangitis (PSC) are rare causes of recurrent ...
Gábor Zsóri, Dóra Illés, László Tiszlavicz, László Czakó   +3 more
doaj   +1 more source

Autoimmune biliary diseases: primary biliary cholangitis and primary sclerosing cholangitis

Pathologica, 2021
Summary Autoimmune cholestatic liver diseases are rare hepato-biliary disorders characterized by a progressive, inflammatory destruction of bile ducts.
S. Sarcognato, D. Sacchi, F. Grillo, N. Cazzagon, L. Fabris, M. Cadamuro, I. Cataldo, C. Covelli, A. Mangia, M. Guido   +9 more
semanticscholar   +1 more source

Primary sclerosing cholangitis: a pre-malignant condition [PDF]

, 2017
Primary sclerosing cholangitis (PSC) is a chronic, progressive, cholestatic liver disease with no known cure. It is a serious condition, and diagnosis comes with an increased risk of developing cancer of the gallbladder, bile ducts or liver.
Gerri Mortimore, Mortimore, Gerri
core   +1 more source

Primary Biliary Cholangitis: an update on treatment. [PDF]

, 2019
Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is a chronic but progressive disease that, over many years, causes damage to bile ducts, leading to cholestasis and, in some patients, cirrhosis.
Mortimore, Gerri
core   +1 more source

Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases

Hepatology, 2018
This American Association for the Study of Liver Diseases (AASLD) 2018 Practice Guidance on Primary Biliary Cholangitis (PBC) is an update of the PBC guidelines published in 2009.
K. Lindor, C. Bowlus, J. Boyer, C. Levy, M. Mayo   +4 more
semanticscholar   +1 more source

Lipocalin-2 as a diagnostic marker for the severity of acute cholangitis [PDF]

Al-Azhar International Medical Journal
Background: One of the most prevalent acute abdominal surgical complications is acute cholangitis, which has a death rate of over 50% according to previous reports.
Nabil Seif El-Deen, Abdemonem Barrak, Mohamed Alboraie, Mohammed Mohammed, Abdel-Aleem Elgendy   +4 more
doaj   +1 more source

Primary sclerosing cholangitis - a comprehensive review.

Journal of Hepatology, 2017
Primary sclerosing cholangitis (PSC) is a rare disorder characterised by multi-focal bile duct strictures and progressive liver disease. Inflammatory bowel disease is usually present and there is a high risk of cholangiocarcinoma and colorectal cancer ...
T. Karlsen, T. Folseraas, D. Thorburn, M. Vesterhus   +3 more
semanticscholar   +1 more source

Evaluation of the Effectiveness of Endoscopic Retrograde Cholangiopancreatography in Patients with Perihilar Cholangiocarcinoma and Its Effect on Development of Cholangitis

Gastroenterology Research and Practice, 2014
Objective. We aimed to determine the effectiveness of endoscopic retrograde cholangiopancreatography (ERCP) in patients with inoperable perihilar cholangiocarcinoma and establish the incidence of cholangitis development following ERCP.
Serkan İpek, Emrah Alper, Cem Cekic, Serkan Cerrah, Mahmut Arabul, Fatih Aslan, Belkis Unsal   +6 more
doaj   +1 more source