Results 91 to 100 of about 54,665 (221)

Click Chemistry and Bioorthogonal Reaction for Aggregation‐Induced Emission Bioconjugates

Aggregate, Volume 7, Issue 3, March 2026.
This review highlights the construction of AIE active bioconjugates via click chemical or bioorthogonal reactions, and their applications in biosensing, bioimaging, and image‐guided treatment. The challenges and perspectives in the area are also discussed.
Xinzhe Yang, Miaomiao Kang, Dong Wang, Ben Zhong Tang   +3 more
wiley   +1 more source

Sex and life experience shape locus coeruleus pretangle tau pathology

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Alzheimer's disease features early a pathology in the locus coeruleus (LC), yet how sex and life experience shape LC vulnerability remains poorly understood. METHODS We expressed pseudophosphorylated human tau (htauE14) in LC neurons of TH‐Cre rats and exposed both sexes to early‐ or late‐life enrichment or stress.
Zia Hasan, Sarah E. Torraville, Tamunotonye Omoluabi, Aida Maziar, Onyedikachi N. Belolise, Lauren A. MacGowan, Cassandra M. Flynn, Camila Reinhardt, Susan G. Walling, Touati Benoukraf, Qi Yuan   +10 more
wiley   +1 more source

Etiology and pathogenesis of duodenal mucosa lesion in chronic pancreatitis

Терапевтический архив, 2009
Aim. To measure content of neuromediators (acetylcholine - Ach, serotonin - 5-NT) and gastrointestinal hormones (cholecystokinine - CCK and secretin) in the blood serum of patients with chronic pancreatitis (CP); to study protective properties of the ...
Lyudmila Vasil'evna Vinokupova, V N Dpozdov, E V Tkachenko, I E Tpubitsyna, G G Vapvanina, L V Vinokurova, V N Drozdov, E V Tkachenko, I E Trubitsyna, G G Varvanina   +9 more
doaj  

Polymorphic variants of the cholecystokinergic system genes: associations with panic disorders

Медицинский совет, 2018
Panic disorder is a widespread socially significant disease, which genetic nature is extremely poorly known. The gene of this neuropeptide (CCK) and its receptors (CCKAR, CCK2R) have being actively studied since the discovery of panicogenic properties of
E. A. Klimov, A. V. Malakhova, L. A. Korobeinikova, Yu. E. Azimova, O. I. Rudko, Z. G. Kokaeva, I. M. Korsunskaya, V. V. Sobolev   +7 more
doaj   +1 more source

Complementary roles of Cholecystokinin- and Parvalbumin-expressing GABAergic neurons in hippocampal network oscillations [PDF]

, 2005
In the hippocampal CA1 area, a relatively homogenous population of pyramidal cells is accompanied by a diversity of GABAergic interneurons. Previously, we found that parvalbumin-expressing basket, axo-axonic, bistratified, and oriens-lacunosum moleculare
Csicsvari, Jozsef, Dalezios, Yannis, Fuentealba, Pablo, Huck, Jojanneke H. J., Kaneko, Takeshi, Klausberger, T, Marton, Laszlo F., O'Neill, Joseph, Papp, Edit, Somogyi, Peter, Suen, Wai Yee, Watanabe, Masahiko   +11 more
core   +2 more sources

Obesity and Natural Products: Mechanisms, Therapeutic Potential, and Future Directions

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
Natural products such as EGCG, berberine, curcumin, and capsaicin modulate key metabolic pathways including AMPK activation, adipogenesis inhibition, and inflammatory signaling. While clinical trials demonstrate modest benefits on body weight and metabolic parameters, translational challenges related to bioavailability, dose feasibility, and regulatory
Ohoud M. Marie, Abdelghafar Abu‐Elsaoud   +1 more
wiley   +1 more source

The Effect of Natural Mineral Water on Regulators of Gastroduodenal Motility in Young Adults: a Comparative Controlled Study

Вестник восстановительной медицины
INTRODUCTION. Drinking balneotherapy has long been successfully used for pathologies of the digestive system. However, the sanogenetic mechanisms of normalization of gastrointestinal motility when using drinking mineral waters have not been sufficiently ...
Aleksey Е. Shklyaev, Daniil D. Kazarin, Kirill V. Maksimov   +2 more
doaj   +1 more source

Growth Performance and Economic Efficiency of SASSO‐C44 Broilers Fed on Diets Containing Varying Levels of Dried Blood–Rumen Mixture as a Substitute for Roasted Soybean Meal

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
This study aimed to investigate the growth performance and economic efficiency of SASSO‐C44 broilers fed diets containing different levels of dried blood–rumen content mixture (DBRCM) instead of roasted soybean meal. Two‐hundred‐day‐old chicks were randomly allocated to five different dietary treatments containing 0%, 20%, 40%, and 60% DBRCM and a ...
Soressa Shuma, Demissu Hundie Senbeta, Malatji Dikeledi Petunia   +2 more
wiley   +1 more source

Naringenin Decreases Retroperitoneal Adiposity and Improves Metabolic Parameters in a Rat Model of Western Diet-Induced Obesity

Metabolites
Background: Obesity is a multifactorial disease with detrimental effects on health and quality of life; unregulated satiety plays a crucial role in food intake and obesity development.
Gabriela López-Almada, J. Abraham Domínguez-Avila, Rosario Maribel Robles-Sánchez, Jonathan Arauz-Cabrera, Gustavo Martínez-Coronilla, Gustavo A. González-Aguilar, Norma Julieta Salazar-López   +6 more
doaj   +1 more source

A receptor-based analysis of local ecosystems in the human brain. [PDF]

, 2017
BackgroundAs a complex system, the brain is a self-organizing entity that depends on local interactions among cells. Its regions (anatomically defined nuclei and areas) can be conceptualized as cellular ecosystems, but the similarity of their functional ...
Janušonis, Skirmantas
core   +1 more source