Results 111 to 120 of about 54,665 (221)

Dentate Gyrus Engrams in Fear and Reward: Mechanistic Principles, Critical Gaps, and Paths to Translation

open access: yesJournal of Neurochemistry, Volume 170, Issue 3, March 2026.
Memories of rewarding experiences powerfully shape behavior, yet when maladaptive, they can drive psychiatric conditions including addiction, depression, and PTSD. Memory traces, or engrams, have been extensively studied for fear memories in the hippocampal dentate gyrus.
Lorianna M. Colón   +2 more
wiley   +1 more source

The Effect of Eight Weeks of Core Stability Training and Chitosan Supplementation on Cholecystokinin (CCK) and Peptide YY (PYY) Levels in Overweight Women: A Randomized Controlled Trial [PDF]

open access: yesJournal of Mazandaran University of Medical Sciences
Background and purpose: Obesity disrupts the secretion of appetite-regulating hormones, such as peptide YY (PYY) and cholecystokinin (CCK), which disrupts natural appetite control mechanisms and promotes excessive food intake and weight gain.
Nasim Rahimi   +3 more
doaj  

Cholecystokinin facilitates motor skill learning by modulating neuroplasticity in the motor cortex

open access: yeseLife
Cholecystokinin (CCK) is an essential modulator for neuroplasticity in sensory and emotional domains. Here, we investigated the role of CCK in motor learning using a single pellet reaching task in mice.
Hao Li   +8 more
doaj   +1 more source

Impact of long‐term maternal high‐fat, high‐sugar feeding on gastric vagal afferent responses and feeding behaviour in mouse offspring

open access: yesExperimental Physiology, Volume 111, Issue 3, Page 1330-1339, 1 March 2026.
Abstract Poor maternal nutrition and excessive gestational weight gain predict future development of obesity in offspring. Preclinically, maternal obesity induced by a high‐fat, high‐sugar diet (HFHSD) induces hyperphagia and obesity in offspring. We hypothesized that this might, in part, reflect reduced peripheral gastric vagal afferent (GVA) satiety ...
Georgia S. Clarke   +7 more
wiley   +1 more source

NPAS4 recruits CCK basket cell synapses and enhances cannabinoid-sensitive inhibition in the mouse hippocampus. [PDF]

open access: yes, 2018
Experience-dependent expression of immediate-early gene transcription factors (IEG-TFs) can transiently change the transcriptome of active neurons and initiate persistent changes in cellular function.
Bloodgood, Brenda L   +6 more
core   +1 more source

Pancreatic adaptive responses in alcohol abuse: Role of the unfolded protein response. [PDF]

open access: yes, 2015
The majority of those who drink excessive amounts of alcohol do not develop pancreatic disease. One overarching hypothesis is that alcohol abuse requires additional risk factors, either environmental or genetic, for disease to occur.
Lugea, Aurelia   +2 more
core   +1 more source

Quantification and correlation of amyloid-β plaque load, glial activation, GABAergic interneuron numbers, and cognitive decline in the young TgF344-AD rat model of Alzheimer’s disease

open access: yesFrontiers in Aging Neuroscience
BackgroundAnimal models of Alzheimer’s disease (AD) are essential tools for investigating disease pathophysiology and conducting preclinical drug testing.
Anett Futácsi   +13 more
doaj   +1 more source

The Mediators of Bile Action on the Exocrine Pancreas [PDF]

open access: yes, 1993
Baba N   +76 more
core   +1 more source

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