Single‐nuclei RNA sequencing reveals heterogeneity within developing GnRH3 neurons in zebrafish
Journal of Neuroendocrinology, Volume 38, Issue 7, July 2026.Abstract Gonadotropin‐releasing hormone (GnRH) is a central regulator of vertebrate reproduction regulating pituitary gonadotropins. In zebrafish, GnRH3 serves as the hypophysiotropic isoform. Its neurons develop by migrating from the nasal placode to the hypothalamus, forming several distinct subpopulations along the migratory path.
Yalong Sun +4 more
wiley +1 more source
Reversal of cholecystokinin-induced persistent stimulation of pancreatic enzyme secretion by dibutyryl cyclic GMP [PDF]
, 1981 When pancreatic acini are first incubated with cholecystokinin, washed to remove free cholecystokinin, and then reincubated in fresh incubation solution, there is a significant residual stimulation of amylase secretion. Butyryl derivatives of cyclic GMP
R. T. Jensen +3 more
core +1 more source
PANIC PROVOCATION STUDIES WITH PLACEBO
Psychiatry and Clinical Psychopharmacology, 2021 Objective: We intended to review studies investigating panic provocation tests using placebo and active drugs in panic disorder patients or in healthy controls.
Erkan Özcan +2 more
doaj
Physiological Reports, Volume 14, Issue 13, July 2026.Abstract This study investigated the combined effects of alcohol and sugar, termed sweetened alcohol consumption (SAC), and tannic acid (TA) intervention on hepatic health in adolescent rats. Sixty‐four male and female 42‐day‐old Sprague–Dawley rats were assigned to control, TA (50 mg/kg), SAC (10% ethanol +20% fructose), or SAC+TA groups and treated ...
Toluwase E. Olanipekun +4 more
wiley +1 more source
Distribution of cells containing mRNA encoding cholecystokinin in the rat central nervous system. [PDF]
, 1991 The distribution of cells containing mRNA encoding cholecystokinin was studied in the rat central nervous system by in situ hybridization histochemistry.
Schiffmann, Serge N. +1 more
core +1 more source
Le récepteur CCK2 dans les cancers : ciblage diagnostique et thérapeutique grâce à la vectorisation de nanoparticules magnétiques [PDF]
, 2012 Le récepteur CCK2 est un récepteur à 7 domaines transmembranaires couplé aux protéines G. D'un point de vue physiologique, le récepteur CCK2 joue un rôle central dans la régulation de la digestion, et agit également au niveau du système nerveux central ...
Sanchez, Claire
core
Modulation of neurotransmitter release by cholecystokinin in the neostriatum and substantia nigra of the rat: regional and receptor specificity [PDF]
, 1996 The effect of cholecystokinin peptides on the release of dynorphin B, aspartate, glutamate, dopamine and GABA in the neostriatum and substantia nigra of the rat was investigated using in vivo microdialysis.
E Pettersson +21 more
core +1 more source
Etiology and pathogenesis of duodenal mucosa lesion in chronic pancreatitis
Терапевтический архив, 2009 Aim. To measure content of neuromediators (acetylcholine - Ach, serotonin - 5-NT) and gastrointestinal hormones (cholecystokinine - CCK and secretin) in the blood serum of patients with chronic pancreatitis (CP); to study protective properties of the ...
Lyudmila Vasil'evna Vinokupova +9 more
doaj
Polymorphic variants of the cholecystokinergic system genes: associations with panic disorders
Медицинский совет, 2018 Panic disorder is a widespread socially significant disease, which genetic nature is extremely poorly known. The gene of this neuropeptide (CCK) and its receptors (CCKAR, CCK2R) have being actively studied since the discovery of panicogenic properties of
E. A. Klimov +7 more
doaj +1 more source
Structural requirements for action of cholecystokinin on enzyme secretion from pancreatic acini [PDF]
, 1982 Using dispersed acini prepared from guinea pig pancreas, we found that the structural requirements for cholecystokinin-induced stimulation of amylase secretion are the same as those for cholecystokinin-induced desensitization of amylase secretion.
R. T. Jensen +3 more
core +1 more source