Results 181 to 190 of about 39,125 (240)
Some of the next articles are maybe not open access.
Hormone and Metabolic Research, 1986
The three classes of CCK antagonists illustrate the various factors governing affinity of the antagonists for the CCK receptor. The major influence in determining potency of the cyclic nucleotide derivatives, amino acid derivatives and C-terminal fragments of CCK, are hydrophobic forces.
P N, Maton, R T, Jensen, J D, Gardner
openaire +2 more sources
The three classes of CCK antagonists illustrate the various factors governing affinity of the antagonists for the CCK receptor. The major influence in determining potency of the cyclic nucleotide derivatives, amino acid derivatives and C-terminal fragments of CCK, are hydrophobic forces.
P N, Maton, R T, Jensen, J D, Gardner
openaire +2 more sources
Radioimmunoassay of cholecystokinin
Digestive Diseases and Sciences, 1983A highly sensitive and specific radioimmunoassay for cholecystokinin (CCK) has been developed. Fully immunoreactive [125I]CCK33 was prepared by chloramine T-catalyzed iodination followed by purification by gel filtration and ion exchange chromatography.
T M, Chang, W Y, Chey
openaire +2 more sources
Comprehensive Physiology, 1980
Abstract The sections in this article are: Definition of Cholecystokinin History of Cholecystokinin Digestive Juice Era Peptide ...
openaire +2 more sources
Abstract The sections in this article are: Definition of Cholecystokinin History of Cholecystokinin Digestive Juice Era Peptide ...
openaire +2 more sources
Current Opinion in Endocrinology, Diabetes & Obesity, 2012
Cholecystokinin (CCK) controls nutrient delivery to the small intestine by inhibiting food intake and gastric emptying. This review deals with recent work shedding new light on how and when.Intestinal I-cells release CCK in response to dietary lipid and protein through mechanisms involving the G-protein-coupled receptors GPR40 and calcium-sensing ...
openaire +2 more sources
Cholecystokinin (CCK) controls nutrient delivery to the small intestine by inhibiting food intake and gastric emptying. This review deals with recent work shedding new light on how and when.Intestinal I-cells release CCK in response to dietary lipid and protein through mechanisms involving the G-protein-coupled receptors GPR40 and calcium-sensing ...
openaire +2 more sources
European Neuropsychopharmacology, 1996
Cholecystokinin (CCK) plays an important role in both the alimentary tract and the central nervous system (CNS). At present it seems to be the most abundant neuropeptide in the CNS. This paper reviews the CCK neuronal system and its interactions with gamma-aminobutyric acid (GABA) and serotonin (5-hydroxytryptamine; 5-HT).
H J, van Megen +3 more
openaire +2 more sources
Cholecystokinin (CCK) plays an important role in both the alimentary tract and the central nervous system (CNS). At present it seems to be the most abundant neuropeptide in the CNS. This paper reviews the CCK neuronal system and its interactions with gamma-aminobutyric acid (GABA) and serotonin (5-hydroxytryptamine; 5-HT).
H J, van Megen +3 more
openaire +2 more sources
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 1988
1. CCK-peptides are distributed throughout the whole brain with the exception of the cerebellum. 2. There is strong evidence that they act as neuromodulators on the noradrenergic, opioid and mainly dopaminergic system. 3. CCK reduces food-intake. However, tolerance occurs, when chronically given.
openaire +2 more sources
1. CCK-peptides are distributed throughout the whole brain with the exception of the cerebellum. 2. There is strong evidence that they act as neuromodulators on the noradrenergic, opioid and mainly dopaminergic system. 3. CCK reduces food-intake. However, tolerance occurs, when chronically given.
openaire +2 more sources
Life Sciences, 1977
Abstract Fourteen normal volunteers were given intravenous or subcutaneous injections of the synthetic C-terminal octapeptide of cholecystokinin (SQ-19, 844) 10 or 20 minutes prior to the ad libitum consumption of a liquid noontime meal. The drug was given in doses of 20 ng/kg, 40 ng/kg, or 80 ng/kg versus equal volumes of a normal saline control in ...
F L, Greenway, G A, Bray
openaire +2 more sources
Abstract Fourteen normal volunteers were given intravenous or subcutaneous injections of the synthetic C-terminal octapeptide of cholecystokinin (SQ-19, 844) 10 or 20 minutes prior to the ad libitum consumption of a liquid noontime meal. The drug was given in doses of 20 ng/kg, 40 ng/kg, or 80 ng/kg versus equal volumes of a normal saline control in ...
F L, Greenway, G A, Bray
openaire +2 more sources
Annual Review of Physiology, 1997
▪ Abstract Cholecystokinin (CCK) is an important hormonal regulator of the digestive process. CCK cells are concentrated in the proximal small intestine, and hormone is secreted into the blood upon the ingestion of food. The physiological actions of CCK include stimulation of pancreatic secretion and gallbladder contraction, regulation of gastric ...
openaire +2 more sources
▪ Abstract Cholecystokinin (CCK) is an important hormonal regulator of the digestive process. CCK cells are concentrated in the proximal small intestine, and hormone is secreted into the blood upon the ingestion of food. The physiological actions of CCK include stimulation of pancreatic secretion and gallbladder contraction, regulation of gastric ...
openaire +2 more sources
Role of cholecystokinin-A and cholecystokinin-B receptors in anxiety
Amino Acids, 2002Evidence from several laboratories indicates that the anxiogenic effects of cholecystokinin (CCK) are mediated by CCKB receptors. However, it has been reported that CCKA receptors have been found in brain and CCKA antagonists have anxiolytic properties.
A M, Hernandez-Gómez +2 more
openaire +2 more sources
Cholecystokinin and Schizophrenia
1986Publisher Summary This chapter presents some of the evidence from animal and clinical studies, implicating cholecystokinin (CCK)-peptides in the pathophysiology of schizophrenia. CCK pathways are extensively distributed throughout the CNS. CCK-immunoreactivity (CCK-IR) is co-localized with dopamine (DA) in some DA neurons projecting to limbic ...
N P, Nair, S, Lal, D M, Bloom
openaire +2 more sources