Results 31 to 40 of about 120,843 (272)

Electrical Monitoring of Vibrio vulnificus–Host Cell Membrane Interactions in Simple and Complex Matrices

Advanced Materials Interfaces, EarlyView.
Supported lipid bilayers coupled with multielectrode array devices offer significant promise for pathogen–host cell membrane interaction studies. This work demonstrates, for the first time, the compatibility of this platform with biological fluids, in this case whole human blood, essential for any future point‐of‐care applications; as well as its ...
Alexandra Wheeler, Zixuan Lu, Jeremy Treiber, Alberto Salleo, Róisín M. Owens   +4 more
wiley   +1 more source

Inhibition of RNase to Attenuate Fungal‐Manipulated Rhizosphere Microbiome and Diseases

Advanced Science, EarlyView.
Fusarium graminearum uses its virulence effector Fg12, a fungal RNase, to manipulate the host rhizosphere microbiome and promote infection. Guanosine monophosphate (GMP) blocks Fg12's RNase activity. This reveals a key pathogen‐microbiota interaction mechanism and proposes GMP as a targeted strategy to disarm this core fungal effector, offering a ...
Bo Yang, Sen Yang, Xiaomi Wang, Yuanwei Zhang, Yao Zhao, Menghuan Tao, Jinyi Zhu, Wanxin Zhang, Yansu Wang, Kaixuan Duan, Yan Wang, Wenwu Ye, Zhenfei Guo, Yuanchao Wang   +13 more
wiley   +1 more source

Contribution of veterinary sector to antimicrobial resistance in One Health compendium: an insight from available Indian evidence

Frontiers in Veterinary Science
The application of antibiotics in the poultry and veterinary sectors is very common practice in India. Owing to the seriousness of antimicrobial resistance (AMR), the present study has illustrated the overall scenario of AMR in the poultry and veterinary
Debjit Chakraborty, Falguni Debnath, Sandip Giri, Shatabdi Saha, Soume Pyne, Raja Chakraverty, Agniva Majumdar, Alok Kumar Deb, Rajesh Bhatia, Shanta Dutta   +9 more
doaj   +1 more source

Epidemiology of typhoid and paratyphoid fever in India

Journal of Infection in Developing Countries, 2008
Enteric fever (typhoid and paratyphoid fever) is a major human bacterial infection. Although the disease is not common in industrialised countries, it remains an important and persistent health problem in developing nations.
Suman Kanungo, Shanta Dutta, Dipika Sur
doaj   +1 more source

Isolation, characterization, and application of a novel polyvalent lytic phage STWB21 against typhoidal and nontyphoidal Salmonella spp.

Frontiers in Microbiology, 2022
Salmonella is one of the common causal agents of bacterial gastroenteritis-related morbidity and mortality among children below 5 years and the elderly populations.
Payel Mondal, Bani Mallick, Moumita Dutta, Shanta Dutta   +3 more
doaj   +1 more source

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

Advanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang, Xinran Ye, Chia‐Kang Ho, Ya Gao, Dongsheng Wen, Jiaming Sun, Yuxin Liu, Yangdan Liu, Guoyuan Wang, Yangbai Sun, Jinyan Zhang, Yifan Zhang, Qingfeng Li   +12 more
wiley   +1 more source

Haitian Variant Vibrio cholerae O1 Strains Manifest Higher Virulence in Animal Models

Frontiers in Microbiology, 2019
Vibrio cholerae causes fatal diarrheal disease cholera in humans due to consumption of contaminated water and food. To instigate the disease, the bacterium must evade the host intestinal innate immune system; penetrate the mucus layer of the small ...
Priyanka Ghosh, Ritam Sinha, Prosenjit Samanta, Dhira Rani Saha, Hemanta Koley, Shanta Dutta, Keinosuke Okamoto, Amit Ghosh, T. Ramamurthy, Asish K. Mukhopadhyay   +9 more
doaj   +1 more source

An Experimental Adult Zebrafish Model for Shigella Pathogenesis, Transmission, and Vaccine Efficacy Studies

Microbiology Spectrum, 2022
Shigellosis has been a menace to society for ages. The absence of an effective vaccine against Shigella, improper sanitation, and unhygienic use of food and water allow the disease to flourish.
Debaki R. Howlader, Ushasi Bhaumik, Prolay Halder, Aishwarya Satpathy, Sounak Sarkar, Mrinalini Ghoshal, Suhrid Maiti, Jeffrey H. Withey, Jiro Mitobe, Shanta Dutta, Hemanta Koley   +10 more
doaj   +1 more source

Integrin‐Piezo1 Axis Drives ECM Remodeling and Invasion of 3D Breast Epithelium

Advanced Science, EarlyView.
Mechanical stiffening of the extracellular matrix around mature mammary acini induces sequential remodeling phases. An early response disrupts the basement membrane and promotes fibronectin secretion, followed by delayed invasion with matrix reorganization and proliferation.
Kabilan Sakthivel, Anna Kotowska, Zhimeng Fan, Ellen Juel Portner, Catherine Merry, Pontus Nordenfelt, Adam Cohen Simonsen, Amanda J. Wright, Vinay S Swaminathan   +8 more
wiley   +1 more source

Quercetin, a flavonoid, combats rotavirus infection by deactivating rotavirus-induced pro-survival NF-κB pathway

Frontiers in Microbiology, 2022
Rotavirus (RV) is the leading cause of acute gastroenteritis and watery diarrhea in children under 5 years accounting for high morbidity and mortality in countries with poor socioeconomic status.
Shreya Banerjee, Rakesh Sarkar, Arpita Mukherjee, Shin-ichi Miyoshi, Kei Kitahara, Prolay Halder, Hemanta Koley, Mamta Chawla-Sarkar   +7 more
doaj   +1 more source