Results 31 to 40 of about 122,361 (297)

Contribution of veterinary sector to antimicrobial resistance in One Health compendium: an insight from available Indian evidence

Frontiers in Veterinary Science
The application of antibiotics in the poultry and veterinary sectors is very common practice in India. Owing to the seriousness of antimicrobial resistance (AMR), the present study has illustrated the overall scenario of AMR in the poultry and veterinary
Debjit Chakraborty, Falguni Debnath, Sandip Giri, Shatabdi Saha, Soume Pyne, Raja Chakraverty, Agniva Majumdar, Alok Kumar Deb, Rajesh Bhatia, Shanta Dutta   +9 more
doaj   +1 more source

Cholera

Current Epidemiology Reports, 2018
This review describes the basic epidemiologic, clinical, and microbiologic aspects of cholera, highlights new developments within these areas, and presents strategies for applying currently available tools and knowledge more effectively.From 1990 to 2016, the reported global burden of cholera fluctuated between 74,000 and 595,000 cases per year ...
William, Davis, Rupa, Narra, Eric D, Mintz   +2 more
openaire   +3 more sources

A Novel Microfluidic System for 3D Epidermis and Full‐Thickness Skin Growth for Nanoparticle Safety Assessment

Advanced Healthcare Materials, EarlyView.
This work presents a novel, dynamically perfused, configurable microfluidic system for epidermis‐only (E and full‐thickness skin (FT SoC) growth, emulating human skin structure and barrier function. Upon TiO2 nanoparticle exposure, the system reveals compromised barrier integrity, reduced metabolic activity, increased permeability, and chemokine‐driven
Samantha Costa, Ana B. Carneiro, Filipa Lebre, João Meneses, Alar Ainla, Cacilda Moura, Ernesto Alfaro‐Moreno, Ana R. Ribeiro   +7 more
wiley   +1 more source

Isolation, characterization, and application of a novel polyvalent lytic phage STWB21 against typhoidal and nontyphoidal Salmonella spp.

Frontiers in Microbiology, 2022
Salmonella is one of the common causal agents of bacterial gastroenteritis-related morbidity and mortality among children below 5 years and the elderly populations.
Payel Mondal, Bani Mallick, Moumita Dutta, Shanta Dutta   +3 more
doaj   +1 more source

Identification of PKN2 and MOB4 as Coordinators of Collective Cell Migration

Advanced Science, EarlyView.
Through a genetic screen, PKN2 and MOB4 are identified as two proteins regulating the healing of an epithelial model wound. PKN2 promotes collective cell migration by maintaining the cohesion of cell monolayers from their lateral junctions, whereas MOB4 restrains collective cell migration and provides a lamellipodial cue for front‐rear polarity in ...
Artem I. Fokin, Yueying Lin, Dmitry Y. Guschin, Hsiang‐Ying Chen, John James, Jie Yan, Pascal Silberzan, Alexis M. Gautreau   +7 more
wiley   +1 more source

Quercetin, a flavonoid, combats rotavirus infection by deactivating rotavirus-induced pro-survival NF-κB pathway

Frontiers in Microbiology, 2022
Rotavirus (RV) is the leading cause of acute gastroenteritis and watery diarrhea in children under 5 years accounting for high morbidity and mortality in countries with poor socioeconomic status.
Shreya Banerjee, Rakesh Sarkar, Arpita Mukherjee, Shin-ichi Miyoshi, Kei Kitahara, Prolay Halder, Hemanta Koley, Mamta Chawla-Sarkar   +7 more
doaj   +1 more source

Delta Opioid Receptors within the Cortico‐Thalamic Circuitry Underlie Hyperactivity Induced by High‐Dose Morphine

Advanced Science, EarlyView.
Morphine activates the excitatory cingulate cortex–intermediate rostrocaudal division of zona incerta (Cg‐ZIm) pathway to drive hyperlocomotion in mice. Inhibiting the Cg‐ZIm pathway attenuates both acute and chronic morphine‐induced hyperlocomotion, while its activation mimics morphine's motor effects.
Chun‐Yue Li, Huiqian Huang, Xiao‐Fan Shen, Ke‐Lei Cao, Di Zheng, Yi Zhu, Shi‐Ze Xie, Xiao‐Dan Yu, Hao Wang, Jia‐Dong Chen, Jie Shi, Yue Li, Min Yan, Xiao‐Ming Li   +13 more
wiley   +1 more source

Morphological, biological, and genomic characterization of a newly isolated lytic phage Sfk20 infecting Shigella flexneri, Shigella sonnei, and Shigella dysenteriae1

Scientific Reports, 2021
Shigellosis, caused by Shigella bacterial spp., is one of the leading causes of diarrheal morbidity and mortality. An increasing prevalence of multidrug-resistant Shigella species has revived the importance of bacteriophages as an alternative therapy to ...
Bani Mallick, Payel Mondal, Moumita Dutta   +2 more
doaj   +1 more source

Screening of Potential Vibrio cholerae Bacteriophages for Cholera Therapy: A Comparative Genomic Approach

Frontiers in Microbiology, 2022
Cholera continues to be a major burden for developing nations, especially where sanitation, quality of water supply, and hospitalization have remained an issue.
Ranjan Kumar Barman, Alok Kumar Chakrabarti, Shanta Dutta   +2 more
doaj   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source