Results 21 to 30 of about 139,742 (259)

Costs of illness due to cholera, costs of immunization and cost-effectiveness of an oral cholera mass vaccination campaign in Zanzibar [PDF]

open access: yes, 2012
BACKGROUND: The World Health Organization (WHO) recommends oral cholera vaccines (OCVs) as a supplementary tool to conventional prevention of cholera. Dukoral, a killed whole-cell two-dose OCV, was used in a mass vaccination campaign in 2009 in Zanzibar.
Claire-Lise Chaignat   +31 more
core   +1 more source

Cholera [PDF]

open access: yesClinical Microbiology Reviews, 1995
Despite more than a century of study, cholera still presents challenges and surprises to us. Throughout most of the 20th century, cholera was caused by Vibrio cholerae of the O1 serogroup and the disease was largely confined to Asia and Africa. However, the last decade of the 20th century has witnessed two major developments in the history of this ...
J B, Kaper, J G, Morris, M M, Levine
openaire   +2 more sources

Sociocultural determinants of anticipated oral cholera vaccine acceptance in three African settings : a meta-analytic approach [PDF]

open access: yes, 2016
Controlling cholera remains a significant challenge in Sub-Saharan Africa. In areas where access to safe water and sanitation are limited, oral cholera vaccine (OCV) can save lives. Establishment of a global stockpile for OCV reflects increasing priority
Merten, Sonja   +19 more
core   +1 more source

Glycyrrhizin, an inhibitor of HMGB1 induces autolysosomal degradation function and inhibits Helicobacter pylori infection

open access: yesMolecular Medicine, 2023
Background Helicobacter pylori is a key agent for causing gastric complications linked with gastric disorders. In response to infection, host cells stimulate autophagy to maintain cellular homeostasis. However, H. pylori have evolved the ability to usurp
Uzma Khan   +8 more
doaj   +1 more source

High Awareness, Poor Practice: The Cholera Prevention Knowledge-Attitude-Practice Gap in Ada Foah, Ghana-A Cross-Sectional Study. [PDF]

open access: yesPublic Health Chall
ABSTRACT Background Cholera persists as a public health threat in Ghana, particularly in coastal communities with inadequate water, sanitation and hygiene (WASH) infrastructure. This study assessed the knowledge, attitudes and practices (KAP) toward cholera among residents of Ada Foah, a high‐risk coastal district in Ghana, to identify gaps and inform ...
Dumevi CY   +11 more
europepmc   +2 more sources

Oral cholera vaccine use in Zanzibar: socioeconomic and behavioural features affecting demand and acceptance [PDF]

open access: yes, 2009
BACKGROUND: Cholera remains a serious public health problem in low-income countries despite efforts in the past to promote oral rehydration therapy as major treatment.
Khatib Ahmed M   +27 more
core   +2 more sources

Improving community coverage of oral cholera mass vaccination campaigns: lessons learned in Zanzibar [PDF]

open access: yes, 2012
BACKGROUND: Recent research in two cholera-endemic communities of Zanzibar has shown that a majority (?94%) of the adult population was willing to receive free oral cholera vaccines (OCVs). Since OCV uptake in the 2009 campaign reached only ?50% in these
Claire-Lise Chaignat   +26 more
core   +1 more source

Gas phase characterization of the noncovalent quaternary structure of Cholera toxin and the Cholera toxin B subunit pentamer [PDF]

open access: yes, 2006
Cholera toxin (CTx) is an AB5 cytotonic protein that has medical relevance in cholera and as a novel mucosal adjuvant. Here, we report an analysis of the noncovalent homopentameric complex of CTx B chain (CTx B5) using electrospray ionization triple ...
Jennings, Keith R.   +15 more
core   +1 more source

Role of integrons, plasmids and SXT elements in multidrug resistance of Vibrio cholerae and Providencia vermicola obtained from a clinical isolate of diarrhea

open access: yesFrontiers in Microbiology, 2015
The isolates of Vibrio cholerae and Providencia vermicola obtained from a diarrhoeal patient were investigated for genetic elements governing their drug resistance phenotypes. Out of fourteen antibiotics tested, V.
Neha eRajpara   +6 more
doaj   +1 more source

Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter

open access: yesGut Pathogens, 2020
Background Metagenomic analysis of the gut microbiome and resistome is instrumental for understanding the dynamics of diarrheal pathogenesis and antimicrobial resistance transmission (AMR).
Rituparna De   +2 more
doaj   +1 more source

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