Costs of illness due to cholera, costs of immunization and cost-effectiveness of an oral cholera mass vaccination campaign in Zanzibar [PDF]
BACKGROUND: The World Health Organization (WHO) recommends oral cholera vaccines (OCVs) as a supplementary tool to conventional prevention of cholera. Dukoral, a killed whole-cell two-dose OCV, was used in a mass vaccination campaign in 2009 in Zanzibar.
Claire-Lise Chaignat +31 more
core +1 more source
Despite more than a century of study, cholera still presents challenges and surprises to us. Throughout most of the 20th century, cholera was caused by Vibrio cholerae of the O1 serogroup and the disease was largely confined to Asia and Africa. However, the last decade of the 20th century has witnessed two major developments in the history of this ...
J B, Kaper, J G, Morris, M M, Levine
openaire +2 more sources
Sociocultural determinants of anticipated oral cholera vaccine acceptance in three African settings : a meta-analytic approach [PDF]
Controlling cholera remains a significant challenge in Sub-Saharan Africa. In areas where access to safe water and sanitation are limited, oral cholera vaccine (OCV) can save lives. Establishment of a global stockpile for OCV reflects increasing priority
Merten, Sonja +19 more
core +1 more source
Background Helicobacter pylori is a key agent for causing gastric complications linked with gastric disorders. In response to infection, host cells stimulate autophagy to maintain cellular homeostasis. However, H. pylori have evolved the ability to usurp
Uzma Khan +8 more
doaj +1 more source
High Awareness, Poor Practice: The Cholera Prevention Knowledge-Attitude-Practice Gap in Ada Foah, Ghana-A Cross-Sectional Study. [PDF]
ABSTRACT Background Cholera persists as a public health threat in Ghana, particularly in coastal communities with inadequate water, sanitation and hygiene (WASH) infrastructure. This study assessed the knowledge, attitudes and practices (KAP) toward cholera among residents of Ada Foah, a highârisk coastal district in Ghana, to identify gaps and inform ...
Dumevi CY +11 more
europepmc +2 more sources
Oral cholera vaccine use in Zanzibar: socioeconomic and behavioural features affecting demand and acceptance [PDF]
BACKGROUND: Cholera remains a serious public health problem in low-income countries despite efforts in the past to promote oral rehydration therapy as major treatment.
Khatib Ahmed M +27 more
core +2 more sources
Improving community coverage of oral cholera mass vaccination campaigns: lessons learned in Zanzibar [PDF]
BACKGROUND: Recent research in two cholera-endemic communities of Zanzibar has shown that a majority (?94%) of the adult population was willing to receive free oral cholera vaccines (OCVs). Since OCV uptake in the 2009 campaign reached only ?50% in these
Claire-Lise Chaignat +26 more
core +1 more source
Gas phase characterization of the noncovalent quaternary structure of Cholera toxin and the Cholera toxin B subunit pentamer [PDF]
Cholera toxin (CTx) is an AB5 cytotonic protein that has medical relevance in cholera and as a novel mucosal adjuvant. Here, we report an analysis of the noncovalent homopentameric complex of CTx B chain (CTx B5) using electrospray ionization triple ...
Jennings, Keith R. +15 more
core +1 more source
The isolates of Vibrio cholerae and Providencia vermicola obtained from a diarrhoeal patient were investigated for genetic elements governing their drug resistance phenotypes. Out of fourteen antibiotics tested, V.
Neha eRajpara +6 more
doaj +1 more source
Background Metagenomic analysis of the gut microbiome and resistome is instrumental for understanding the dynamics of diarrheal pathogenesis and antimicrobial resistance transmission (AMR).
Rituparna De +2 more
doaj +1 more source

