Results 131 to 140 of about 77,065 (293)

In Vitro Selection of a Single-Stranded DNA Molecular Recognition Element against Clostridium difficile Toxin B and Sensitive Detection in Human Fecal Matter

open access: yesJournal of Nucleic Acids, 2015
Toxin B is one of the major virulence factors of Clostridium difficile, a bacterium that is responsible for a significant number of diarrhea cases in acute care settings. Due to the prevalence of C. difficile induced diarrhea, rapid and correct diagnosis
Ka Lok Hong   +3 more
doaj   +1 more source

Developing downstream processes for the purification of recombinant proteins and small molecules from Nicotiana benthamiana biomass

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Nicotiana benthamiana (Australian tobacco) has become a major host for plant‐based recombinant protein production, especially using transient expression. Once a candidate protein has been designed and produced in a suitable variety (e.g. facilitated humanized glycosylation) under reproducible conditions (e.g.
J. F. Buyel
wiley   +1 more source

PENGARUH EKSTRAK DIKLOROMETAN JAHE (Zingiber officinale Roscoe) TERHADAP PENGIKATAN TOKSIN KOLERA B-subunit CONJUGASI (FITC) PADA RECEPTOR SEL HIBRIDOMA LV DAN CACO-2 [Effect of Ginger (Zingiber officinale Roscoe) Dichloromethane Extract on Inhibition of Cholera Toxin B-subunit Conjugated FITC Binding to Receptor on LV Hibridome and Caco-2 Cells]

open access: yesJurnal Teknologi dan Industri Pangan, 2003
Cholera toxin is main factor that responsibility of watery diarrhea. The objectives of this investigation was to study the effect of ginger extract (GDE) in blocking cholera toxin binding to receptors of LV hybridome and Caco-2 cells.Analysis of toxin
Radiati, L.E 1)   +7 more
doaj  

Molecular Dynamics Simulation of Cholera Toxin A-1 Polypeptide

open access: yesOpen Chemistry, 2016
A molecular dynamics (MD) simulation study of the enzymatic portion of cholera toxin; cholera toxin A-1 polypeptide (CTA1) was performed at 283, 310 and 323 K.
Badshah Syed Lal   +2 more
doaj   +1 more source

Identification of potential cell surface targets in patient‐derived cultures toward photoimmunotherapy of high‐grade serous ovarian cancer

open access: yesPhotochemistry and Photobiology, EarlyView.
Through mRNA sequencing, proteomics, and flow cytometry, we identified potential cell surface targets toward tumor‐targeted, activatable photoimmunotherapy (taPIT) in advanced high‐grade serous ovarian cancers (HGSOCs) with low EGFR expression. The reliance on EGFR overexpression has been a major limitation of taPIT, which this study seeks to address ...
Sudip Timilsina   +3 more
wiley   +1 more source

Cholera Toxin Production and Localization in Vesicles of Vibrio cholerae El Tor Genovariants

open access: yesПроблемы особо опасных инфекций
The aim was to assess the level of toxin production in Vibrio cholerae El Tor genovariants and to determine the localization of cholera toxin in vesicles.Materials and methods. The work is performed on typical strains and genovariants of V.
L. P. Alekseeva   +4 more
doaj   +1 more source

The Role of Foxes in Transmitting Zoonotic Bacteria to Humans: A Scoping Review

open access: yesZoonoses and Public Health, EarlyView.
ABSTRACT Zoonotic diseases inflict substantial burdens on human and animal populations worldwide, and many of these infections are bacterial. An Australian study investigating environmental risk factors for Buruli ulcer in humans detected the causative agent, Mycobacterium ulcerans, in the faeces of wild foxes, a novel finding that suggests foxes may ...
Emma C. Hobbs   +6 more
wiley   +1 more source

The mechanotransduction protein STOML3 is required for proprioceptor plasticity following peripheral nerve regeneration

open access: yesExperimental Physiology, EarlyView.
Abstract Nerve regeneration is associated with the plasticity of sensory neurons such that even muscle afferents directed to the skin form mechanosensitive receptive fields appropriate for the new target. STOML3 is an essential mechanotransduction component in many cutaneous mechanoreceptors. Here, we asked whether STOML3 is required for functional and
Julia Haseleu   +2 more
wiley   +1 more source

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