Effectiveness of two doses of Euvichol-plus oral cholera vaccine in response to the 2017/2018 outbreak: a matched case–control study in Lusaka, Zambia [PDF]
Introduction Zambia experienced a major cholera outbreak in 2017–2018, with more than 5905 cases reported countrywide, predominantly from the peri-urban slums of Lusaka city.
Victor M Mukonka+16 more
doaj +3 more sources
Effectiveness of one dose of oral cholera vaccine in response to an outbreak: a case-cohort study [PDF]
Background: Oral cholera vaccines represent a new effective tool to fight cholera and are licensed as two-dose regimens with 2–4 weeks between doses.
Dr. Andrew S Azman, PhD+24 more
doaj +4 more sources
An overview of VaxchoraTM, a live attenuated oral cholera vaccine [PDF]
Cholera remains a public health threat among the least privileged populations and regions affected by conflicts and natural disasters. Together with Water, Sanitation and Hygiene practices, use of oral cholera vaccines (OCVs) is a key tool to prevent ...
Tarun Saluja+4 more
doaj +3 more sources
Urban cholera transmission hotspots and their implications for reactive vaccination: evidence from Bissau city, Guinea bissau. [PDF]
BackgroundUse of cholera vaccines in response to epidemics (reactive vaccination) may provide an effective supplement to traditional control measures.
Andrew S Azman+7 more
doaj +15 more sources
Cholera causes significant morbidity and mortality worldwide. For travelers, the risk of developing cholera per month of stay in a developing country is approximately 0.001%-0.01%, and cholera may present as traveler's diarrhea. In the United States, only a poorly tolerated, marginally effective, parenterally administered, phenol-inactivated vaccine is
Edward T. Ryan, Stephen B. Calderwood
openalex +6 more sources
Effectiveness of reactive oral cholera vaccination in rural Haiti: a case-control study and bias-indicator analysis [PDF]
Background: Between April and June, 2012, a reactive cholera vaccination campaign was done in Haiti with an oral inactivated bivalent whole-cell vaccine.
Dr. Louise C Ivers, MBBCh+10 more
doaj +3 more sources
Evaluation of oral cholera vaccine (Euvichol-Plus) effectiveness against Vibrio cholerae in Bangladesh: an interim analysis [PDF]
Introduction Millions of Euvichol-Plus doses have been deployed from the global oral cholera vaccine stockpile in over 20 cholera-affected countries. However, information on Euvichol-Plus’s effectiveness is limited.
Amanda Tiffany+20 more
doaj +2 more sources
Safety of the recombinant cholera toxin B subunit, killed whole-cell (rBS-WC) oral cholera vaccine in pregnancy. [PDF]
Mass vaccinations are a main strategy in the deployment of oral cholera vaccines. Campaigns avoid giving vaccine to pregnant women because of the absence of safety data of the killed whole-cell oral cholera (rBS-WC) vaccine. Balancing this concern is the
Ramadhan Hashim+24 more
doaj +3 more sources
Epidemiologic and Genomic Surveillance of Vibrio cholerae and Effectiveness of Single-Dose Oral Cholera Vaccine, Democratic Republic of the Congo [PDF]
We conducted 4 years of epidemiologic and genomic surveillance of single-dose effectiveness of a killed whole-cell oral cholera vaccine (kOCV) and Vibrio cholerae transmission in the Democratic Republic of the Congo.
Christine Marie George+14 more
doaj +2 more sources