Results 71 to 80 of about 664,130 (306)

What in the world is global health? A conceptual analysis

Developing World Bioethics, EarlyView.
Abstract This article suggests that the concept of global health – and to an extent the field that it designates ‐ is problematic in various ways. Within public health, the concept of the ‘public’ has been widely investigated. However, “global health” has been introduced in academic, policy, and public discussion with comparably lower level of ...
Alberto Giubilini
wiley   +1 more source

A missing dimension in measures of vaccination impacts [PDF]

, 2014
Immunological protection, acquired from either natural infection or vaccination, varies among hosts, reflecting underlying biological variation and affecting population-level protection.
AE Barskey, Andrew R. Wargo, Antonio Coutinho, Carlota Rebelo, CJ Struchiner, DL Smith, F Ben-Ami, G Dwyer, Gael Kurath, Glenn F. Rall, Graham F. Medley, HA Druett, IM Longini Jr, M. Gabriela M. Gomes, Marc Lipsitch, ME Halloran, MGM Gomes, MP Zwart, P Aaby, PG Smith, RB Hornick, WA Furumoto, WA Furumoto   +22 more
core   +8 more sources

Killed Whole-Cell Oral Cholera Vaccine Induces CCL20 Secretion by Human Intestinal Epithelial Cells in the Presence of the Short-Chain Fatty Acid, Butyrate

Frontiers in Immunology, 2018
Short-chain fatty acids (SCFAs), such as acetate, butyrate, and propionate, modulate immune responses in the gut. However, the effect of SCFAs on mucosal vaccine-induced immune cell migration is poorly understood.
Ju-Ri Sim, Seok-Seong Kang, Da-Hye Lee, C. Yun, S. Han   +4 more
semanticscholar   +1 more source

Feasibility and costs of a targeted cholera vaccination campaign in Ethiopia

Human Vaccines & Immunotherapeutics, 2018
Shanchol™, a WHO-prequalified oral cholera vaccine (OCV), has been used to control endemic cholera in Asia, as well as in emergencies and outbreaks elsewhere.
Samuel Teshome, Sachin Desai, Jerome H. Kim, Dires Belay, Vittal Mogasale   +4 more
doaj   +1 more source

Effectiveness of reactive oral cholera vaccination in rural Haiti: a case-control study and bias-indicator analysis

The Lancet Global Health, 2015
Background: Between April and June, 2012, a reactive cholera vaccination campaign was done in Haiti with an oral inactivated bivalent whole-cell vaccine.
Dr. Louise C Ivers, MBBCh, Isabelle J Hilaire, MD, Jessica E Teng, MPH, Charles P Almazor, MD, J Gregory Jerome, MD, Ralph Ternier, MD, Jacques Boncy, MD, Josiane Buteau, MD, Prof. Megan B Murray, MD, Jason B Harris, MD, Molly F Franke, ScD   +10 more
doaj   +1 more source

Production of putative enhanced oral cholera vaccine strains that express toxin-coregulated pilus. [PDF]

PLoS ONE, 2017
The use of whole cell killed (WCK) oral cholera vaccines is an important strategy for cholera prevention in endemic areas. To overcome current vaccine limitations, we engineered strains of V.
Caitlyn A Hauke, Ronald K Taylor
doaj   +1 more source

Developing downstream processes for the purification of recombinant proteins and small molecules from Nicotiana benthamiana biomass

Plant Biotechnology Journal, EarlyView.
Summary Nicotiana benthamiana (Australian tobacco) has become a major host for plant‐based recombinant protein production, especially using transient expression. Once a candidate protein has been designed and produced in a suitable variety (e.g. facilitated humanized glycosylation) under reproducible conditions (e.g.
J. F. Buyel
wiley   +1 more source

Current and future cholera vaccines

Vaccine, 2020
Cholera remains a major global public health problem that is primarily linked to insufficient access to safe water and proper sanitation. Oral Cholera Vaccine (OCV) has been recommended as an additional public health tool along with WASH in cholera endemic countries and in areas at risk for outbreaks.
Hanif Shaikh, Julia Lynch, Jerome Kim, Jean-Louis Excler   +3 more
openaire   +3 more sources

Use of verbal autopsy to determine mortality patterns in an urban slum in Kolkata, India

Bulletin of the World Health Organization, 2010
OBJECTIVE: To define mortality patterns in an urban slum in Kolkata, India, in the context of a cholera and typhoid fever project. METHODS: In a well-defined population that was under surveillance for 18 months, we followed a dynamic cohort of 63788 ...
Suman Kanungo, Ataru Tsuzuki, Jacqueline L Deen, Anna Lena Lopez, Krisnan Rajendran, Byomkesh Manna, Dipika Sur, Deok Ryun Kim, Vinay Kumar Gupta, R Leon Ochiai, Mohammad Ali, Lorenz von Seidlein, Sujit K Bhattacharya, John D Clemens   +13 more
doaj  

Structural Design and Immunogenicity of a Novel Self‐Adjuvanting Mucosal Vaccine Candidate for SARS‐CoV‐2 Expressed in Plants

Plant Biotechnology Journal, EarlyView.
ABSTRACT Mucosal vaccination for COVID‐19 to boost preexisting though insufficient systemic and local/mucosal immunity remains an attractive prospect but there are currently no licensed mucosal vaccines against this infection. Here, using a plant expression system, we developed a novel mucosal vaccine platform for respiratory viruses and demonstrated ...
Mi‐Young Kim, Andy Cano Tran, Ju Kim, Humblenoble Stembridge Ayuk, Adam Sparrow, Lorenzo Bossi, Megan Brown, Emil Joseph Vergara, Kathrin Göritzer, Elisabetta Groppelli, Tae‐Ho Kwon, Julian K. C. Ma, Yong‐Suk Jang, Rajko Reljic   +13 more
wiley   +1 more source