Results 21 to 30 of about 537 (178)

Zinc Treatment Reverses and anti-Zn-Regulated miRs Suppress Esophageal Carcinomas In Vivo [PDF]

, 2023
Esophageal squamous cell carcinoma (ESCC) is a deadly disease with few prevention or treatment options. ESCC development in humans and rodents is associated with Zn deficiency (ZD), inflammation, and overexpression of oncogenic microRNAs: miR-31 and miR ...
Brydges, Christopher R, Croce, Carlo M, Farber, John, Fiehn, Oliver, Fong, Louise, Huebner, Kay, Jing, Ruiyan, Smalley, Karl   +7 more
core   +1 more source

Geochemical Investigation of Tar Balls Collected on a Beach on Žirje Island (Croatia) Using Petroleum Biomarkers [PDF]

, 2021
Tar balls are frequently reported as indicators of the extent of marine pollution owing to spill incidents of crude oil or petroleum products. Representative tar ball samples collected on a beach on Žirje Island, Croatia, were geochemically characterised
Cuculić, Vlado, Fajković, Hana, Marinović, Slavica   +2 more
core   +2 more sources

Soft-tissue evidence for homeothermy and crypsis in a Jurassic ichthyosaur [PDF]

, 2018
Ichthyosaurs are extinct marine reptiles that display a notable external similarity to modern toothed whales. Here we show that this resemblance is more than skin deep.
Ahlberg, Per E., Alwmark, Carl, Engdahl, Anders, Eriksson, Mats E., Gustafsson, Ola, Hauff, Rolf, Ito, Shosuke, Jarenmark, Martin, Kear, Benjamin P., Kuriyama, Takeo, Lindgren, Johan, Malmberg, Per, Marone, Federica, Ojika, Makoto, Rodríguez-Meizoso, Irene, Sachs, Sven, Schweitzer, Mary H., Sjövall, Peter, Thiel, Volker, Thomen, Aurélien, Uvdal, Per, Wakamatsu, Kazumasa, Zheng, Wenxia   +22 more
core   +1 more source

Marine Natural Products from the Yucatan Peninsula [PDF]

, 2020
[Abstract] Mexico is one of the three areas of the world with the greatest terrestrial and cultural biological diversity. The diversity of Mexican medicinal flora has been studied for a long time and several bioactive compounds have been isolated.
Jiménez, Carlos, Lenis Rojas, Oscar, Pech-Puch, Dawrin, Pérez Povedano, Mar Anabel, Rodríguez, Jaime   +4 more
core   +1 more source

Experimental Assessment of the Effects of Substrate Choice on the Duration of Chemical Signals in Fecal Scent‐Marks of Free‐Ranging Iberian Wolves

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Chemical communication, typically based on feces, urine, and glandular secretions, often deposited as substrate scent marks, plays a key role in social organization and communication among many mammals, especially carnivores. This study assesses experimentally whether the type of substrate chosen for fecal deposition and the temperature ...
Elisa Espartosa, Jose Martin, Isabel Barja   +2 more
wiley   +1 more source

High cholesterol absorption efficiency enhances proatherogenic properties of low‐density lipoprotein particles

Journal of Internal Medicine, Volume 299, Issue 6, Page 711-725, June 2026.
Abstract Background and Aims High cholesterol absorption efficiency is determined by genetic variation in small intestinal sterol transporters and affects one‐third of individuals. Their risk for atherosclerotic cardiovascular disease (ASCVD) is increased compared with low cholesterol absorbers, despite similar serum lipid concentrations.
Katariina Öörni, Lauri Äikäs, Maija Ruuth, Feven Tigistu‐Sahle, Reijo Käkelä, Ingmar Wester, Helena Gylling, Piia Simonen   +7 more
wiley   +1 more source

Ancient steroids establish the Ediacaran fossil Dickinsonia as one of the earliest animals [PDF]

, 2020
The enigmatic Ediacara biota (571 million to 541 million years ago) represents the first macroscopic complex organisms in the geological record and may hold the key to our understanding of the origin of animals.
Bobrovskiy, Ilya, Brocks, Jochen, Hallmann, Christian O. E., Hope, Janet, Ivantsov, Andrey, Nettersheim, Benjamin   +5 more
core   +1 more source

2025 Consensus Clinical Management Guidelines for Niemann‐Pick Disease Type C

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT In 2018, the International Niemann‐Pick Disease Alliance (INPDA) and the International Niemann‐Pick Disease Registry (INPDR) developed and published comprehensive clinical management guidelines to support inclusive and standardized care pathways in Niemann‐Pick disease type C (NPC)—an ultra‐rare, autosomal recessive, neurovisceral lysosomal ...
Tarekegn Hiwot, Forbes D. Porter, Tatiana Bremova‐Ertl, Uma Ramaswami, Caroline Hastings, Bénédicte Héron, Justin Hopkin, Joella Melville, Hernan Amartino, Mireia del Toro, Federica Deodato, Fatih Ezgü, Paul Gissen, James B. Gibson, Can Ficicioglu, Roberto Giugliani, Orna Staretz‐Chacham, Frances Platt, Nathalie Guffon, Kristina Julich, Nikola Kresojević, Anna Lehman, Yann Nadjar, Susanne A. Schneider, Simon Jones, Eugen Mengel, Michel Tchan, Mark Walterfang, Ozlem Goker‐Alpan, Charlotte Dawson, Sandra Cowie, Toni Mathieson, Elizabeth Berry‐Kravis, Marc C. Patterson   +33 more
wiley   +1 more source

Polyomic characterisation of polyene drug resistance in Leishmania spp. [PDF]

, 2020
Amphotericin B is the compound of choice for the treatment of leishmaniasis, however a definitive mode of action and full knowledge of causes of resistance to this polyene are still poor.
Alpizar Sosa, Edubiel Arturo
core  

Geochemical markers and polycyclic aromatic hydrocarbons in solvent extracts from diesel engine particulate matter [PDF]

, 2016
Exhaust particulate from compression ignition (CI) engines running on engine and chassis dynamometers was studied. Particulate dichloromethane extracts were qualitatively and quantitatively analyzed for polycyclic aromatic hydrocarbons (PAHs) and ...
Bielaczyc, Piotr, Fabiańska, Monika, Konieczyński, Jan, Kozielska, Barbara, Woodburn, Joseph   +4 more
core   +2 more sources