Empirical Chiroptical Analyses of Vicinal Bromochloro Natural Products by van't Hoff's Principle of Optical Superposition: Assignment of the C-16 Configurations of Callophycols A and B. [PDF]
J Org ChemA simple empirical method is described that allows the assignment of absolute configurations of natural products containing chiral vicinal bromochloro (VBC) units, including the bromochloro substituted isoprenyl units present in the structures of ...
Molinski TF.
europepmc +3 more sources
Vendozoa and selective forces on animal origin and early diversification: reply to Dufour and McIlroy (2017). [PDF]
Philos Trans R Soc Lond B Biol Sci, 2018 Cavalier-Smith T.
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6-Hydroxyimino-5α-cholestane [PDF]
Acta Crystallographica Section E Structure Reports Online, 2012 The title compound, C(27)H(47)NO, is a steroid derivative composed of a saturated carbon fused-ring framework with an alkyl side chain. Ring bond lengths have normal values with an average of 1.533 (2) Å, while the cholestane side chain shows an average bond length of 1.533 (2) Å.
Uzzaman, Shams +4 more
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Towards the synthesis of calotropin and related cardenolides from 3-epiandrosterone : A-ring related modifications [PDF]
, 2020 Calotropin and related cardiac glycosides isolated from plants such ascalotropis gigantearepresent an interesting target for biological investigations and are based on a cardiac steroid that is doubly connected to a sugar moiety. This naturally occurring
Bräse, Stefan +2 more
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Stereoselective synthesis of perhydrobenzo[4.5.6]cholestanes [PDF]
, 1992 An intramolecular Michael-aldol reaction sequence has been developed for the stereocontrolled synthesis of pentacyclic steroids! with the new six-membered ring attached to the C(4) and C(6) positions. Cholesterol was converted into 3β-hydroxycholest-4-en-6-one by standard methods, and the corresponding 3α-isomer was obtained through Mitsunobu inversion.
Borry, Joost
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Chemical Composition and Physical Properties of “Pale Yellow” Naphtalan [PDF]
, 2011 The Pale Yellow (PY) Naphthalan is potentially a new treatment modality for some oral mucosal and dermatological diseases. Its chemical composition and physical properties were studied by standard and sophisticated methods.
Anđa Alajbeg +6 more
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Mass spectrometric analysis of epimeric 3α/3β functionalized steroids. [PDF]
, 2007 Tandem mass spectrometry (MS/MS) using an atmospheric pressure chemical ionization (APCI) source in positive mode (+) reveals different intensity ratios of two fragment peaks of the epimeric cholestane derivatives synthesized from 3{460}- or 3β ...
Almeida, Paulo +5 more
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Arylmethylamino steroids as antiparasitic agents [PDF]
, 2017 In search of antiparasitic agents, we here identify arylmethylamino steroids as potent compounds and characterize more than 60 derivatives. The lead compound 1o is fast acting and highly active against intraerythrocytic stages of chloroquine-sensitive ...
Becker, Katja +19 more
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Cholestane Glycosides from Solanum abutiloides. III.
Chemical and Pharmaceutical Bulletin, 2000 Four new cholestane glycosides, named abutilosides D (1), E (2), F (3) and G (4), were isolated from the fresh roots of Solanum abutiloides. By chemical and spectroscopic evidence, their structures were elucidated as 26-O-beta-D-glucopyranosyl 3beta,16alpha,26-trihydroxy-5alpha-cholestan-22-one 3-O-beta-D-xylopyranosyl-(1-->2)-alpha-L-rhamnopyranosyl ...
H, Yoshimitsu, M, Nishida, T, Nohara
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Nontargeted evaluation of the fate of steroids during wastewater treatment by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry [PDF]
, 2016 Emerging organic contaminants in wastewater are usually analyzed by targeted approaches, and especially estrogens have been the focus of environmental research due to their high hormonal activity. The selection of specific target compounds means, however,
Kopperi, Matias +3 more
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